Results 51 to 60 of about 2,412 (177)

Desmosterol and 7-dehydrocholesterol concentrations in post mortem brains of depressed people: The role of trazodone

Translational Psychiatry, 2022
Major depressive disorder (MDD) is a common, disabling, and heterogeneous condition that responds unpredictably to current treatments. We previously showed an association between depressive symptoms and plasma concentrations of two cholesterol precursors,
Basar Cenik, Jayme M. Palka, Bonne M. Thompson, Jeffrey G. McDonald, Carol A. Tamminga, Can Cenik, E. Sherwood Brown   +6 more
doaj   +1 more source

Experimental Assessment of the Effects of Substrate Choice on the Duration of Chemical Signals in Fecal Scent‐Marks of Free‐Ranging Iberian Wolves

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 5, Page 462-475, June 2026.
ABSTRACT Chemical communication, typically based on feces, urine, and glandular secretions, often deposited as substrate scent marks, plays a key role in social organization and communication among many mammals, especially carnivores. This study assesses experimentally whether the type of substrate chosen for fecal deposition and the temperature ...
Elisa Espartosa, Jose Martin, Isabel Barja   +2 more
wiley   +1 more source

From pollen provision to pollinator: Species‐specific sterol assimilation by wild bees in urban landscapes

Functional Ecology, Volume 40, Issue 6, Page 1906-1920, June 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐driven landscape change, particularly urbanization, is reshaping pollinator communities, yet the functional traits that mediate species persistence remain poorly understood. Dietary specialization is commonly used to predict species vulnerability.
Yan Yang, Joan Casanelles‐Abella, Marco Moretti, Consuelo M. De Moraes, Mark C. Mescher, Pengjuan Zu   +5 more
wiley   +1 more source

Sterol composition of shellfish species commonly consumed in the United States

Food & Nutrition Research, 2012
Background: Shellfish can be a component of a healthy diet due to a low fat and high protein content, but the cholesterol content of some species is often cited as a reason to limit their consumption. Data on levels of non-cholesterol sterols in commonly
Katherine M. Phillips, David M. Ruggio, Jacob Exler, Kristine Y. Patterson   +3 more
doaj   +1 more source

Targeting Brain Cholesterol Homeostasis in Alzheimer's Disease: Mechanisms and Therapeutic Perspectives

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan, Ameer Y. Taha, Walter Swardfager   +2 more
wiley   +1 more source

What dictates the accumulation of desmosterol in the developing brain? [PDF]

The FASEB Journal, 2012
The brain is the most cholesterol‐enriched tissue in the body. During brain development, desmosterol, an immediate precursor of cholesterol, transiently accumulates up to 30% of total brain sterols. This massive desmosterol deposition appears to be present in all mammalian species reported so far, including humans, but how it is ...
Greco Dario, Ikonen Elina, Jansen Maurice, Wang Wei, Greco Dario, Ikonen Elina, Jansen Maurice, Wang Wei   +7 more
openaire   +7 more sources

Mapping molluscan endocrinology: a systematic and critical appraisal

Biological Reviews, Volume 101, Issue 2, Page 970-1002, April 2026.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis, Thomas H. Miller, Olwenn V. Martin, Alice Baynes   +3 more
wiley   +1 more source

Effect of exogenous steroids on sterol synthesis in L-cell mouse fibroblasts

Journal of Lipid Research, 1971
A number of steroids have been tested in an L-cell tissue culture system to determine their effects on cellular sterol biosynthesis and cellular growth.
GEORGE H. ROTHBLAT, MICHELE K. BUCHKO
doaj   +1 more source

Plasma advanced glycation end products and soluble receptor for advanced glycation end products as indicators of sterol content in human carotid atherosclerotic plaques

Diabetes & Vascular Disease Research, 2022
Advanced glycation end products (AGEs) are independently related to cardiovascular disease (CVD) and favor cholesterol and oxysterol accumulation in macrophage foam cells.
Raphael S Pinto, Guilherme S Ferreira, Gina Camillo R Silvestre, Monique de Fátima M Santana, Valéria S Nunes, Lucas Ledesma, Paula R Pinto, Sayonara Ivana S de Assis, Ubiratan F Machado, Erasmo S da Silva, Marisa Passarelli   +10 more
doaj   +1 more source

A Cluster of Three snoRNAs Including Jouvence Required in the Gut Determines Lifespan and Confers Neuroprotection Through Metabolic Parameters

Aging Cell, Volume 25, Issue 4, April 2026.
The disruption of a cluster of three snoRNAs in the epithelium of the gut deregulates the lipid and sterol (including the cholesterol) homeostasis. At the whole‐organism level, this chronic deregulation, all along life, decreases lifespan and leads to neurodegenerative lesions in old flies.
Sara Al Issa, Théo Gauvrit, Patricia Daira, Nathalie Bernoud‐Hubac, Jean‐René Martin   +4 more
wiley   +1 more source