Results 41 to 50 of about 2,350 (174)

Comparison of the metabolism of cholesterol, cholestanol, and β-sitosterol in L-cell mouse fibroblasts

Journal of Lipid Research, 1971
The following data have been obtained from comparative studies on the metabolism of cholesterol, cholestanol, and β-sitosterol by L-cell mouse fibroblasts.
GEORGE H. ROTHBLAT, CHRISTINA H. BURNS
doaj   +1 more source

A Transient Inflammatory Response Induced by Lipopolysaccharide Infusion Lowers Markers of Endogenous Cholesterol and Bile Acid Synthesis in Healthy Normocholesterolemic Young Men

Biomedicines, 2023
Inflammation is associated with changes in plasma lipids, lipoproteins, and cholesterol efflux capacity (CEC). It is unknown if the changes in lipids and lipoproteins during inflammation are related to changes in cholesterol absorption, synthesis, and ...
Sultan Mashnafi, Sabine Baumgartner, Ronald P. Mensink, Desiree Perlee, Lonneke A. van Vught, Dieter Lütjohann, Jogchum Plat   +6 more
doaj   +1 more source

Enteromorpha prolifera Polysaccharide Alleviates Type 2 Diabetes via the Gut Microbiota–Liver Axis to Modulate Cholesterol Metabolism

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Enteromorpha prolifera polysaccharides may help restore lipid metabolism homeostasis by gently remodeling the gut microbiota to enrich beneficial bacteria and SCFAs, which in turn appears to modulate hepatic functions through the portal vein by downregulating cholesterol synthesis and promoting its metabolism. This coordinated process potentially leads
Liuying Zhu, Xusheng Wen, Wenrong Zhu, Xueqian Hu, Yanqun Xu, Xin Peng   +5 more
wiley   +1 more source

A highly sensitive method for analysis of 7-dehydrocholesterol for the study of Smith-Lemli-Opitz syndrome[S]

Journal of Lipid Research, 2014
We describe a highly sensitive method for the detection of 7-dehydrocholesterol (7-DHC), the biosynthetic precursor of cholesterol, based on its reactivity with 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD) in a Diels-Alder cycloaddition reaction.
Wei Liu, Libin Xu, Connor Lamberson, Dorothea Haas, Zeljka Korade, Ned A. Porter   +5 more
doaj   +1 more source

Experimental Assessment of the Effects of Substrate Choice on the Duration of Chemical Signals in Fecal Scent‐Marks of Free‐Ranging Iberian Wolves

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 5, Page 462-475, June 2026.
ABSTRACT Chemical communication, typically based on feces, urine, and glandular secretions, often deposited as substrate scent marks, plays a key role in social organization and communication among many mammals, especially carnivores. This study assesses experimentally whether the type of substrate chosen for fecal deposition and the temperature ...
Elisa Espartosa, Jose Martin, Isabel Barja   +2 more
wiley   +1 more source

Serum squalene and noncholesterol sterols before and after delivery in normal and cholestatic pregnancy

Journal of Lipid Research, 1996
Mechanisms of hyperlipidemia were studied by measurement of serum lipid concentrations and the ratios of cholesterol precursors (squalene, delta 8-cholestenol, desmosterol, and lathosterol), plant sterols (campesterol and sitosterol), and cholestanol (a ...
K Nikkilä, S Riikonen, M Lindfors, T A Miettinen   +3 more
doaj   +1 more source

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation

EMBO Molecular Medicine, 2023
Liver X receptor (LXR) agonism has theoretical potential for treating NAFLD/NASH, but synthetic agonists induce hyperlipidemia in preclinical models.
Enchen Zhou, Xiaoke Ge, Hiroyuki Nakashima, Rumei Li, Hendrik J P van der Zande, Cong Liu, Zhuang Li, Christoph Müller, Franz Bracher, Yassene Mohammed, Jan Freark de Boer, Folkert Kuipers, Bruno Guigas, Christopher K Glass, Patrick C N Rensen, Martin Giera, Yanan Wang   +16 more
doaj   +1 more source

The effect of hydroxychloroquine on cholesterol metabolism in statin treated patients after myocardial infarction

Atherosclerosis Plus, 2023
Background and aims: To evaluate the effect of hydroxychloroquine (HCQ) on serum and lipoprotein lipids and serum biomarkers of cholesterol synthesis and absorption in myocardial infarction patients with a high-dose statin. Methods: Myocardial infarction
Lotta Ulander, Piia Simonen, Heli Tolppanen, Otto Hartman, Tuomas T. Rissanen, Kari K. Eklund, Marita Kalaoja, Mika Kurkela, Mikko Neuvonen, Mikko Niemi, Janne T. Backman, Helena Gylling, Juha Sinisalo   +12 more
doaj   +1 more source

From pollen provision to pollinator: Species‐specific sterol assimilation by wild bees in urban landscapes

Functional Ecology, Volume 40, Issue 6, Page 1906-1920, June 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐driven landscape change, particularly urbanization, is reshaping pollinator communities, yet the functional traits that mediate species persistence remain poorly understood. Dietary specialization is commonly used to predict species vulnerability.
Yan Yang, Joan Casanelles‐Abella, Marco Moretti, Consuelo M. De Moraes, Mark C. Mescher, Pengjuan Zu   +5 more
wiley   +1 more source

Desmosterol and 7-dehydrocholesterol concentrations in post mortem brains of depressed people: The role of trazodone

Translational Psychiatry, 2022
Major depressive disorder (MDD) is a common, disabling, and heterogeneous condition that responds unpredictably to current treatments. We previously showed an association between depressive symptoms and plasma concentrations of two cholesterol precursors,
Basar Cenik, Jayme M. Palka, Bonne M. Thompson, Jeffrey G. McDonald, Carol A. Tamminga, Can Cenik, E. Sherwood Brown   +6 more
doaj   +1 more source