Results 31 to 40 of about 2,350 (174)
Unique lipids of primate spermatozoa: desmosterol and docosahexaenoic acid.
Journal of Lipid Research, 1993 Spermatozoa represent a tissue readily accessible for study after various exogenous perturbations. To characterize the lipid composition of monkey sperm and to establish a baseline from which dietary or pharmaceutical influences may then be evaluated, we
DS Lin +4 more
doaj +1 more source
Biomolecules, 2023 The concurrent use of several medications is a common practice in the treatment of complex psychiatric conditions. One such commonly used combination is aripiprazole (ARI), an antipsychotic, and trazodone (TRZ), an antidepressant.
Zeljka Korade +5 more
doaj +1 more source
Limb malformations of rat fetuses exposed to a distal inhibitor of cholesterol biosynthesis
Journal of Lipid Research, 2002 Triparanol, an inhibitor of desmosterol Δ24 reductase, produces a high rate of limb malformations in rat fetuses exposed at gestational day 10 (gd 10) to a single oral dose (150–200 mg/kg) given to the pregnant dam.
Françoise Chevy +3 more
doaj +1 more source
Pathway of cholesterol biosynthesis in the brain of the neonatal rat
Journal of Lipid Research, 1966 Suckling rats were killed at various intervals after intraperitoneal injection of acetate-1-14C and their brain sterols were analyzed by column, thin-layer, paper, and gas-liquid chromatography.
Thomas J. Holstein +2 more
doaj +1 more source
The role of soluble fiber intake in patients under highly effective lipid-lowering therapy
Nutrition Journal, 2011 Background It has been demonstrated that statins can increase intestinal sterol absorption. Augments in phytosterolemia seems related to cardiovascular disease.
Rezende Vinicius M +9 more
doaj +1 more source
Preparation of desmosterol from fucosterol.
Chemical and Pharmaceutical Bulletin, 1976 Desmosteryl acetate, a useful key intermediate for synthesis of the metabolites of vitamin D3, was synthesized from fucosterol by two routes ; (1) 24, 28-epoxyfucosteryl acetate was treated with solid acids such as zeolite, silica-alumina and alumina-boria to give desmosteryl acetate in a yield of 16%-40%, (2) dehydration of 24-hydroxycholesteryl ...
TAKESHITA, TORU +2 more
openaire +2 more sources
iMetaMed, EarlyView.Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang +7 more
wiley +1 more source
Journal of Lipid Research, 2010 Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences circulating cholesterol concentrations and subsequent coronary heart disease (CHD) risk.
Nirupa R. Matthan +9 more
doaj +1 more source
Desmosterol May Replace Cholesterol in Lipid Membranes [PDF]
Biophysical Journal, 2005 Recently, knockout mice entirely lacking cholesterol have been described as showing only a mild phenotype. For these animals, synthesis of cholesterol was interrupted at the level of its immediate precursor, desmosterol. Since cholesterol is a major and essential constituent of mammalian cellular membranes, we asked whether cholesterol with its ...
Huster, Daniel +4 more
openaire +2 more sources
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background Hydrogen sulfide (H2S) is an endogenous gasotransmitter regulating redox balance, inflammation, and vascular tone, but reproducing the spatial and kinetic features of endogenous production remains challenging. We examine sulfurous thermal waters as natural contexts of sustained H2S exposure, using the Saturnia springs (Tuscany ...
Elisabetta Ferrara +6 more
wiley +1 more source