Results 51 to 60 of about 4,329 (200)

The role of soluble fiber intake in patients under highly effective lipid-lowering therapy

Nutrition Journal, 2011
Background It has been demonstrated that statins can increase intestinal sterol absorption. Augments in phytosterolemia seems related to cardiovascular disease.
Rezende Vinicius M, Moreno Ronilson A, Borges Ney C, Helfenstein Tatiana, Moreira Flávio T, Kasmas Soraia H, Fonseca Francisco A, Ramos Silvia C, Silva Fernanda C, Izar Maria C   +9 more
doaj   +1 more source

Sterol profiles in plasma and erythrocyte membranes in patients with Smith-Lemli-Opitz syndrome: a six-year experience [PDF]

, 2011
Background: This study reports our experience over the last six years in the diagnosis of Smith-Lemli-Opitz syndrome and other inborn errors of cholesterol biosynthesis.
A. Nappi, DELLO RUSSO, ANTONIO, G. Corso, GELZO, MONICA, P. Pianese, R. Barone, S. Clericuzio   +6 more
core   +1 more source

High cholesterol absorption efficiency enhances proatherogenic properties of low‐density lipoprotein particles

Journal of Internal Medicine, EarlyView.
Abstract Background and Aims High cholesterol absorption efficiency is determined by genetic variation in small intestinal sterol transporters and affects one‐third of individuals. Their risk for atherosclerotic cardiovascular disease (ASCVD) is increased compared with low cholesterol absorbers, despite similar serum lipid concentrations.
Katariina Öörni, Lauri Äikäs, Maija Ruuth, Feven Tigistu‐Sahle, Reijo Käkelä, Ingmar Wester, Helena Gylling, Piia Simonen   +7 more
wiley   +1 more source

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia [PDF]

, 2018
Metabolic reprogramming has emerged as a crucial regulator of immune cell activation, but how systemic metabolism influences immune cell metabolism and function remains to be investigated.
Baardman, Jeroen, de Winther, Menno P J, Denis, Simone W, Dinkova-Kostova, Albena T, Houtkooper, Riekelt H, Knatko, Elena V, Lutgens, Esther, Neele, Annette E, O'neill, Luke A, Prange, Koen H M, Ryan, Dylan G, Speijer, Dave, Van den Bossche, Jan, van der Velden, Saskia, van Weeghel, Michel, Verberk, Sanne G S, Witte, Maarten E, Wüst, Rob C I   +17 more
core   +8 more sources

Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial

Journal of Lipid Research, 2010
Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences circulating cholesterol concentrations and subsequent coronary heart disease (CHD) risk.
Nirupa R. Matthan, Nancy Resteghini, Michele Robertson, Ian Ford, James Shepherd, Chris Packard, Brendan M. Buckley, J. Wouter Jukema, Alice H. Lichtenstein, Ernst J. Schaefer   +9 more
doaj   +1 more source

Concentration-Dependent Diversification Effects of Free Cholesterol Loading on Macrophage Viability and Polarization [PDF]

, 2015
Background/Aims: The accumulation of free cholesterol in atherosclerotic lesions has been well documented in both animals and humans. In studying the relevance of free cholesterol buildup in atherosclerosis, contradictory results have been generated ...
Li, Ningjun, Li, Pin-Lan, Xu, Xiaoyang, Zhang, Aolin, Zhang, Fan   +4 more
core   +3 more sources

Mapping molluscan endocrinology: a systematic and critical appraisal

Biological Reviews, Volume 101, Issue 2, Page 970-1002, April 2026.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis, Thomas H. Miller, Olwenn V. Martin, Alice Baynes   +3 more
wiley   +1 more source

Comparison of the metabolism of cholesterol, cholestanol, and β-sitosterol in L-cell mouse fibroblasts

Journal of Lipid Research, 1971
The following data have been obtained from comparative studies on the metabolism of cholesterol, cholestanol, and β-sitosterol by L-cell mouse fibroblasts.
GEORGE H. ROTHBLAT, CHRISTINA H. BURNS
doaj   +1 more source

A Transient Inflammatory Response Induced by Lipopolysaccharide Infusion Lowers Markers of Endogenous Cholesterol and Bile Acid Synthesis in Healthy Normocholesterolemic Young Men

Biomedicines, 2023
Inflammation is associated with changes in plasma lipids, lipoproteins, and cholesterol efflux capacity (CEC). It is unknown if the changes in lipids and lipoproteins during inflammation are related to changes in cholesterol absorption, synthesis, and ...
Sultan Mashnafi, Sabine Baumgartner, Ronald P. Mensink, Desiree Perlee, Lonneke A. van Vught, Dieter Lütjohann, Jogchum Plat   +6 more
doaj   +1 more source

Sterolomics: State of the Art, Developments, Limitations and Challenges [PDF]

, 2017
Sterolomics can be thought of as the quantitative determination of the entire complement of molecules based on the cyclopentanoperhydrophenanthrene skeleton in a system. Mass spectrometry is the dominant analytical technology employed. In this article we
Abdel-Khalik, Clayton, Cobice, Dzeletovic, Fahy, Griffiths, Griffiths, Griffiths, Griffiths, Jones, Karu, Liebisch, Lütjohann, McDonald, Saeed, Schroepfer, Sempos, William J. Griffiths, Wudy, Xu, Xu, Yuqin Wang   +21 more
core   +1 more source