Results 31 to 40 of about 389,547 (323)

The Importance of Developmental Science for Studies in Bullying and Victimization [PDF]

, 2012
Research on bullying and victimization, especially in school settings, has become an important area of developmental research, with strong practical implications. In this article we overview some considerations from neuropsychology, quantitative genetics,
Jones, Alice P., Smith, Peter K.
core   +1 more source

Theoretical Models of Neural Development

iScience, 2018
Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues.
Geoffrey J. Goodhill
doaj   +1 more source

Aberrant cortical projections to amygdala GABAergic neurons contribute to developmental circuit dysfunction following early life stress

iScience, 2023
Summary: Early life stress (ELS) results in enduring dysfunction of the corticolimbic circuitry, underlying emotional and social behavior. However, the neurobiological mechanisms involved remain elusive.
Joni Haikonen, Jonas Englund, Shyrley Paola Amarilla, Zoia Kharybina, Alexandra Shintyapina, Kristel Kegler, Marta Saez Garcia, Tsvetomira Atanasova, Tomi Taira, Henrike Hartung, Sari E. Lauri   +10 more
doaj   +1 more source

Intrinsic Motivation Systems for Autonomous Mental Development [PDF]

, 2007
Exploratory activities seem to be intrinsically rewarding for children and crucial for their cognitive development. Can a machine be endowed with such an intrinsic motivation system?
Hafner, Véréna, Kaplan, Frédéric, Oudeyer, Pierre-Yves   +2 more
core   +9 more sources

Neuroblasts contribute to oligodendrocytes generation upon demyelination in the adult mouse brain

iScience, 2022
Summary: After demyelinating insult, the neuronal progenitors of the adult mouse sub-ventricular zone (SVZ) called neuroblasts convert into oligodendrocytes that participate to the remyelination process.
Bilal El Waly, Claire Bertet, Mathilde Paris, Marie Falque, Pierre Milpied, Karine Magalon, Myriam Cayre, Pascale Durbec   +7 more
doaj   +1 more source

Selective postnatal excitation of neocortical pyramidal neurons results in distinctive behavioral and circuit deficits in adulthood

iScience, 2021
Summary: In genetic and pharmacological models of neurodevelopmental disorders, and human data, neural activity is altered within the developing neocortical network. This commonality begs the question of whether early enhancement in excitation might be a
William E. Medendorp, Andreas Bjorefeldt, Emmanuel L. Crespo, Mansi Prakash, Akash Pal, Madison L. Waddell, Christopher I. Moore, Ute Hochgeschwender   +7 more
doaj   +1 more source

Translational neuroscience measures of fear conditioning across development: applications to high-risk children and adolescents [PDF]

, 2013
Several mental illnesses, including anxiety, can manifest during development, with onsets in late childhood. Understanding the neurobiological underpinnings of risk for anxiety is of crucial importance for early prevention and intervention approaches ...
Kaitlyn L Gamwell, Karin Nylocks, Tanja Jovanovic   +2 more
core   +1 more source

KIBRA regulates activity-induced AMPA receptor expression and synaptic plasticity in an age-dependent manner

iScience, 2022
Summary: A growing body of human literature implicates KIBRA in memory and neurodevelopmental disorders. Memory and the cellular substrates supporting adaptive cognition change across development.
Matthew L. Mendoza, Lilyana D. Quigley, Thomas Dunham, Lenora J. Volk   +3 more
doaj   +1 more source

Developing thoughts about what might have been [PDF]

, 2014
Recent research has changed how developmental psychologists understand counterfactual thinking or thoughts of what might have been. Evidence suggests that counterfactual thinking develops over an extended period into at least middle childhood, depends on
Beck, Sarah R., Riggs, Kevin, Riggs, Kevin J.   +2 more
core   +1 more source

A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons

iScience, 2020
Summary: Mammalian brain development critically depends on proper thyroid hormone signaling, via the TRα1 nuclear receptor. The downstream mechanisms by which TRα1 impacts brain development are currently unknown. In order to investigate these mechanisms,
Sabine Richard, Romain Guyot, Martin Rey-Millet, Margaux Prieux, Suzy Markossian, Denise Aubert, Frédéric Flamant   +6 more
doaj   +1 more source