Results 121 to 130 of about 25,080 (259)

Multimodal Characterization of Glymphatic‐Related Magnetic Resonance Imaging Markers in Huntington's Disease: A Multi‐Cohort Retrospective Study

Annals of Neurology, EarlyView.
Objective To characterize magnetic resonance imaging (MRI)‐based glymphatic surrogates in Huntington's disease (HD) using MRI measures of perivascular diffusivity and structural perivascular alterations across multiple large cohorts. Methods We analyzed 2,731 MRI sessions from 880 participants across 3 large retrospective HD cohorts.
Alexia Solomon, Zexi Wang, Francesco Sanvito, Zheng Zhou, Adys Mendizabal, Jingwen Yao   +5 more
wiley   +1 more source

Bioengineered human brain organoids and organ-on-chip platforms for exposure-aware assessment of developmental neurotoxicity induced by general anesthetics and sedatives. [PDF]

Front Bioeng Biotechnol
Yue J, Pan C, Lu C, Song Z.
europepmc   +1 more source

developmental neurotoxicity study

Citation: 'developmental neurotoxicity study' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10598 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire   +1 more source

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

Advanced NanoBiomed Research, EarlyView.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen, Liwen Zhang, Helen Forgham, Jiayuan Zhu, Xumin Huang, Changkui Fu, Ibrahim Javed, Thomas P. Davis, Ruirui Qiao   +8 more
wiley   +1 more source

Developmental Neurotoxicity of Alcohol from Neuronal Basis to Behavioural Outcomes: A Comprehensive Review. [PDF]

Neurol Int
Smimih K, Azzouhri C, El-Mansoury B, Draoui A, Lahouaoui H, Bitar A, Merzouki M, El Hiba O.   +7 more
europepmc   +1 more source

Zebrafish behavioral assessment as a first-tier whole-organism NAM for developmental neurotoxicity: A multi-laboratory evaluation. [PDF]

Neurotoxicology
Truong L, Hsieh JH, Ellis L, Jaka O, Muriana A, Molina-Martínez B, Del Pozo A, Schiavone V, Di Donato V, Sanz CM, Tanguay RL, Hessel E, Ryan K.   +12 more
europepmc   +1 more source

Controversies in anesthesia-induced developmental neurotoxicity. [PDF]

Best Pract Res Clin Anaesthesiol, 2023
Useinovic N, Jevtovic-Todorovic V.
europepmc   +1 more source

Maternal exposure to the thyroperoxidase-inhibiting pesticide amitrole induces hypothyroidism and developmental neurotoxicity in the rat brain. [PDF]

Front Endocrinol (Lausanne)
Ramhøj L, Ardenkjær-Skinnerup J, Davidsen N, Ford J, Kuehn C, Frädrich C, Köhrle J, Gilbert M, Svingen T, Axelstad M.   +9 more
europepmc   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Leveraging developmental neurotoxicity data in zebrafish embryos through the use of artificial intelligence methods. [PDF]

Front Toxicol
Heusinkveld HJ, Hessel EVS, Zwart EP, Gremmer ER, Pennings JLA.   +4 more
europepmc   +1 more source