Results 181 to 190 of about 23,637 (256)

Unveiling the hidden dangers: a review of non-apoptotic programmed cell death in anesthetic-induced developmental neurotoxicity. [PDF]

Cell Biol Toxicol
Sun H, Yisi Shan, Cao L, Wu X, Chen J, Yuan R, Qian M.   +6 more
europepmc   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye, M. B. Komane, A. P. Manyisane, R. Manganyi   +3 more
wiley   +1 more source

Neurotoxicity and Developmental Neurotoxicity of Copper Sulfide Nanoparticles on a Human Neuronal In-Vitro Test System. [PDF]

Int J Mol Sci
Stern M, Botha N, Cloete KJ, Maaza M, Tan S, Bicker G.   +5 more
europepmc   +1 more source

Formulation‐Dependent Cytotoxic Effects of Commercial and Analytical‐Grade Mancozeb in C6 Glial Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Mancozeb (MZ) is a widely used dithiocarbamate fungicide composed of manganese (Mn) and zinc (Zn) complexes. Increasing concern has been raised regarding its occupational and human health relevance, particularly due to its neurotoxic potential associated with Mn‐related cellular dysfunction.
Lavínia Lazzarotti, Felipe Vanz, Karina Giacomini Varela, Viviane Glaser, Diego de Carvalho, Aline Pertile Remor   +5 more
wiley   +1 more source

Life Course Considerations in Environmental Health: Developmental Neurotoxicity of Domoic Acid at Doses Below Acute Effect Levels in Adult Humans. [PDF]

Birth Defects Res
Campbell MA, Murphy SR, Klasing SA, Niknam Y, Iyer P, Stanton B, Zeise L.   +6 more
europepmc   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source

The Differential Developmental Neurotoxicity of Valproic Acid on Anterior and Posterior Neural Induction of Human Pluripotent Stem Cells. [PDF]

Int J Stem Cells
Kim J, Park SH, Sun W.
europepmc   +1 more source

Bisphenol Analog‐Induced Cytotoxicity: Unraveling Endoplasmic Reticulum (ER) Stress and Apoptotic Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is increasingly replaced by structural analogs, yet their safety remains insufficiently characterized. This study investigated whether BPA and selected analogs, bisphenol AF (BPAF), bisphenol AP (BPAP), bisphenol P (BPP), and bisphenol E (BPE), induce cytotoxicity through activation of endoplasmic reticulum (ER) stress and ...
Rafia Afroze Rifa, Ramon Lavado
wiley   +1 more source

Unraveling the signaling network between dysregulated microRNA and mRNA expression in sevoflurane-induced developmental neurotoxicity in rat. [PDF]

Heliyon
Wang Y, Men X, Huang X, Qiu X, Wang W, Zhou J, Zhou Z.   +6 more
europepmc   +1 more source

Somatosensory Disturbance and Long‐Term Exposure to Methylmercury: A Comprehensive Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chronic exposure to methylmercury remains a significant public health concern, particularly in populations with high fish consumption. Somatosensory disturbances are among the most frequently reported neurological manifestations, even at exposure levels below internationally established safety thresholds. This review aims to synthesize current
Leonardo Breno do Nascimento de Aviz, Carolina Fonte de Aviz, Fabiana Costa Cardoso, Laura dos Santos Barros, Raphaely Cristiny Sanches Progênio, Mariângela Moreno Domingues, José Maria Farah Costa Júnior, Saul Rassy Carneiro, Carlos Araújo da Costa, Maria da Conceição Nascimento Pinheiro   +9 more
wiley   +1 more source