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Roquinimex inhibits dextran sodium sulfate-induced murine colitis

Inflammation Research, 2003
Roquinimex is a modulator of the immune system and has been shown to attenuate induction of several inflammatory and autoimmune diseases. The objective of the present study was to determine the efficacy of roquinimex in a model of murine colitis.For this purpose, Balb/c mice were exposed to 5% dextran sodium sulfate (DSS) in the drinking water for five
Q, Liu   +6 more
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Dextran Sulfate Sodium-Induced Colitis in Immunodeficient Rats

Digestive Diseases and Sciences, 2000
To examine the morphology of colitis and study the role of the immune system in colitis, we compared colitis in immunocompetent Wistar-Kyoto rats with that in spontaneously hypertensive rats, known to have T-cell dysfunction. Rats were treated with 3% dextran sulfate in drinking water for periods ranging from 3 to 60 days.
K, Shichijo   +3 more
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Zearalenone can relieve dextran sulfate sodium‐induced inflammatory reaction

Journal of Biochemical and Molecular Toxicology, 2018
AbstractIn this study, we investigated the influence of zearalenone (ZEA) on the dextran sulfate sodium (DSS)‐induced colitis model both in vitro and in vivo. Our results show that the mRNA levels of IL‐1β, IL‐18, NLRP3, ASC, and caspase‐1 in the DSS+ZEA‐treated group are lower than those in either the DSS or ZEA group, and the protein expression ...
Chenchen Ding   +5 more
openaire   +2 more sources

Embelin ameliorates dextran sodium sulfate-induced colitis in mice

International Immunopharmacology, 2011
Embelin has been used to treat fever, inflammatory diseases, and a variety of gastrointestinal ailments for thousands of years. Although reports indicate that embelin has anti-inflammatory and anti-tumor effects, its effects on ulcerative colitis have not been previously explored.
Kalyan, Kumar G   +4 more
openaire   +2 more sources

Agaricus bisporusAttenuates Dextran Sulfate Sodium-Induced Colitis

Journal of Medicinal Food, 2014
Agaricus bisporus (white button mushroom, WBM) is widely consumed in most countries and is reported to have anti-inflammatory and antioxidant activities. However, little is known regarding its effects in dextran sulfate sodium (DSS)-induced colitis, which are related to dysfunction of intestinal immunity. The aim of the present study was to investigate
Min Young, Um   +5 more
openaire   +2 more sources

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