Results 241 to 250 of about 98,007 (275)

Dextran sodium sulfate alters cytokine production in macrophages in vitro.

Die Pharmazie, 2016
Macrophages have been assumed to have a crucial role in the development of inflammatory bowel disease (IBD). However, involvement of intestinal macrophages in IBD onset and functional alterations of macrophages during IBD development has not been clarified.
Kono, Y., Miyoshi, S., Fujita, T.
openaire   +2 more sources

Intestinal E-cadherin Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis

Digestive Diseases and Sciences, 2015
E-cadherin is a cell adhesion protein with crucial roles in development, tissue homeostasis, and disease. Loss of E-cadherin in the adult intestinal epithelium disrupts tissue architecture and is associated with impaired localization and function of goblet and Paneth cells, reduced expression of antibacterial factors, and deficiency in clearing ...
Jessica I, Grill, Jens, Neumann, Felix, Hiltwein, Frank T, Kolligs, Marlon R, Schneider   +4 more
openaire   +2 more sources

Keratinocyte Growth Factor Ameliorates Dextran Sodium Sulfate Colitis in Mice

Digestive Diseases and Sciences, 1999
Keratinocyte growth factor (KGF) is emerging as an important mediator of mucosal defense and repair in the colon. The aim of the present study was to evaluate and further characterize the effects of exogenous KGF administration utilizing the dextran sodium sulfate (DSS) model of colitis in mice.
B, Egger, F, Procaccino, I, Sarosi, J, Tolmos, M W, Büchler, V E, Eysselein   +5 more
openaire   +2 more sources

Dextran sulfate sodium-induced colitis in piglets

2018
Inflammatory bowel disease (IBD) results from complex interactions between genetic and environmental factors.Although a genetic contribution has been proven, dietary factors have also shown to play a role in the developmentof IBD.This study aims to investigate the effect of adding red meatto the diet of piglets in a dextran sodium sulfate (DSS ...
Nielsen, Katrine Dalby, Schramm, Andreas, Purup, Stig, Lauridsen, Charlotte, Canibe, Nuria   +4 more
openaire   +1 more source

PACAP provides colonic protection against dextran sodium sulfate induced colitis

Journal of Cellular Physiology, 2008
AbstractPituitary adenylate cyclase‐activating polypeptide (PACAP) plays a crucial role in immunity and inflammation. Our aim was to obtain insight in the role of PACAP in experimental colitis in mice and thus its possible role in inflammatory bowel disease.
Yasu-Taka, Azuma, Kiyomi, Hagi, Norihito, Shintani, Mitsuru, Kuwamura, Hidemitsu, Nakajima, Hitoshi, Hashimoto, Akemichi, Baba, Tadayoshi, Takeuchi   +7 more
openaire   +2 more sources

Daucosterol suppresses dextran sulfate sodium (DSS)-induced colitis in mice

International Immunopharmacology, 2019
The effects of daucosterol have been identified in cancer therapy and neuronal diseases. However, the regulatory function of daucosterol in DSS-induced colitis has not yet been investigated. In this study, we evaluated the immunological and therapeutic effects of daucosterol in a mouse model of dextran sulfate sodium (DSS)-induced colitis.
Jin, Jang, Su-Man, Kim, Su-Min, Yee, Eun-Mi, Kim, Eun-Hee, Lee, Ha-Rim, Choi, Young-Sil, Lee, Won-Kyung, Yang, Han-Young, Kim, Kun-Hoae, Kim, Hyung-Sik, Kang, Seung-Hyung, Kim   +11 more
openaire   +2 more sources

Human neutrophil peptide-1 aggravates dextran sulfate sodium-induced colitis

Inflammatory Bowel Diseases, 2012
Human neutrophil peptide (HNP)-1, HNP-2, and HNP-3 (HNP-1-3) are useful biomarkers for ulcerative colitis (UC). The precise roles of these peptides in UC are poorly understood, however. The aim of this study was to determine whether HNP-1 affects disease activity in mice with experimental colitis.Experimental colitis was induced in BALB/c or severe ...
Shinichi, Hashimoto, Hirofumi, Uto, Shuji, Kanmura, Toshio, Sakiyama, Manei, Oku, Yuji, Iwashita, Rie, Ibusuki, Fumisato, Sasaki, Kazunari, Ibusuki, Yoichiro, Takami, Akihiro, Moriuchi, Makoto, Oketani, Akio, Ido, Hirohito, Tsubouchi   +13 more
openaire   +2 more sources

Osteopontin deficiency protects mice from dextran sodium sulfate-induced colitis

Inflammatory Bowel Diseases, 2006
Osteopontin (OPN), a secreted glycoprotein that promotes TH1 immune responses, is involved in several inflammatory conditions. Recently, OPN plasma levels have been demonstrated to be elevated in patients with Crohn's disease. From this evidence, we investigated in the present study whether OPN deficiency protects mice against dextran sodium sulfate ...
Jian, Zhong, Erik R M, Eckhardt, Helieh S, Oz, Dennis, Bruemmer, Willem J S, de Villiers   +4 more
openaire   +2 more sources

Curcumin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Molecular Nutrition & Food Research
AbstractScope: Curcumin (Cur), with diverse pharmacological properties, shows anti‐obesity, immunomodulatory, and anti‐inflammatory effects. Its role in ulcerative colitis complicated by obesity remains unclear.Methods and results: Here, colitis is induced in obese mice using dextran sulfate sodium (DSS), followed by administration of Cur at a dosage ...
Zeng‐Ping Kang, Qiu‐Ping Xiao, Jia‐Qi Huang, Meng‐Xue Wang, Jie Huang, Si‐Yi Wei, Nian Cheng, Hai‐Yan Wang, Duan‐Yong Liu, You‐Bao Zhong, Hai‐Mei Zhao   +10 more
openaire   +2 more sources

Fundamentals, status and promise of sodium-based batteries

Nature Reviews Materials, 2021
Robert E Usiskin, Yaxiang Lu, Jelena Popovic   +2 more
exaly