Results 61 to 70 of about 98,007 (275)

β-ionone prevents dextran sulfate sodium-induced ulcerative colitis and modulates gut microbiota in mice

Food Innovation and Advances
β-ionone has various biological activities, such as anti-inflammatory, antimicrobial, and anticancer effects. The pathogenesis of ulcerative colitis is correlated with immune dysfunction, intestinal barrier damage, and gut microbiota imbalance.
Jingjing Fang, Tingting Liu, Yumeng Wang, Seong-Gook Kang, Kunlun Huang, Tao Tong   +5 more
doaj   +1 more source

Antiplatelet agents’-ticagrelol and eptifibatide-safety in experimental colitis in mice

The Turkish Journal of Gastroenterology, 2020
Background/Aims: To evaluate the side effects of two antiplatelet agents - ticagrelor and eptifibatide - in mice with experimentally-induced inflammatory bowel disease. Methods and Material: This study was designed as a controlled, animal, drug safety
Stanko S. Petrovic, Milijana M. Vasiljevska, Slobodan D. Obradovic, Dino K. Tarabar, Radoje B. Doder, Ivana J. Majstorovic, Marijana D. Petrovic, Zvonko M. Magic, Bojana M. Cikota, Nenad J. Perisic, Irina A. Brcerevic, Nebojsa S. Manojlovic, Nemanja K. Rancic   +12 more
doaj   +1 more source

Comparison of the new OPS Imaging technique with intravital microscopy: Analysis of the colon microcirculation [PDF]

, 2002
Background. The OPS imaging technique has been introduced for in vivo assessment of microcirculation in humans. The aim of this study was to validate the new technique against intravital fluorescence microscopy (IFM) for the visualization of colon ...
Biberthaler, Peter, Langer, S.
core   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Microplastic effects on mouse colon in normal and colitis conditions: A literature review [PDF]

PeerJ
Background Taking into account the global spread of microplastic (MP) pollution, the problem of the MP impact on human health is relevant. MP enters the organism predominantly with water and food, and is mostly detected in the large intestine. Therefore,
Natalia Zolotova, Dzhuliia Dzhalilova, Ivan Tsvetkov, Maria Silina, Nikolai Fokichev, Olga Makarova   +5 more
doaj   +2 more sources

Over-Expression of CD200 Protects Mice from Dextran Sodium Sulfate Induced Colitis. [PDF]

PLoS ONE, 2016
CD200:CD200 receptor (CD200R) interactions lead to potent immunosuppression and inhibition of autoimmune inflammation. We investigated the effect of "knockout"of CD200 or CD200R, or over-expression of CD200, on susceptibility to dextran sodium sulfate ...
Zhiqi Chen, Kai Yu, Fang Zhu, Reginald Gorczynski   +3 more
doaj   +1 more source

Goji berry attenuates dextran sulfate sodium‐induced colitis

The FASEB Journal, 2015
Inflammatory bowel diseases (IBD) including ulcerative colitis (UC) and Crohn's disease, are gastrointestinal disorders characterized by intestinal inflammation. Goji berry ( Lycium barbarum ), also known as wolfberry, is a traditional Chinese herbal medicine, which has long been recognized ...
Yifei Kang, Yansong Xue, Min Du, Meijun Zhu   +3 more
openaire   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Oxysterol-mediated modulation of intestinal inflammation: insights into sex differences and GPR183 signaling

Cellular and Molecular Life Sciences
Background and aims Oxysterols, oxidized derivatives of cholesterol, play complex roles in inflammatory processes, but their specific functions in inflammatory bowel diseases remain incompletely understood.
Hafsa Ameraoui, Joan Bestard-Escalas, Martin Roumain, Adam Laghouati, Pauline Bottemanne, Mireille Alhouayek, Giulio G. Muccioli   +6 more
doaj   +1 more source

Dextran sodium sulfate (DSS) induces necrotizing enterocolitis-like lesions in neonatal mice. [PDF]

PLoS ONE, 2017
Necrotizing enterocolitis (NEC) is an inflammatory bowel disease of preterm human newborns with yet unresolved etiology. An established neonatal murine model for NEC employs oral administration of lipopolysaccharides (LPS) combined with hypoxia ...
Marco Ginzel, Xiaoyan Feng, Joachim F Kuebler, Christian Klemann, Yi Yu, Reinhard von Wasielewski, Joon-Keun Park, Mathias W Hornef, Gertrud Vieten, Benno M Ure, Torsten Kaussen, Jan Hendrik Gosemann, Steffi Mayer, Anne Suttkus, Martin Lacher   +14 more
doaj   +1 more source