Results 91 to 100 of about 9,214 (193)

Determination of Dextromethorphan and Dextrorphan in Urine Using Bar Adsorptive Microextraction Followed by Gas Chromatography–Mass Spectrometry Analysis

Separations
Over the past few years, the misuse of medications has progressively increased, posing a significant public health concern. This study proposed the development and validation of an alternative and greener analytical method for the determination of ...
Marisa H. Maria, Margarida Fonseca, Alexandre Quintas, Nuno R. Neng   +3 more
doaj   +1 more source

Dextromethorphan [PDF]

Reactions Weekly, 2019
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Risk factors of developing rhabdomyolysis in cough medicine abusers presented to the accident and emergency departments in Hong Kong during 2008–2023

Hong Kong Journal of Emergency Medicine
Introduction Rhabdomyolysis was observed in cough medicine abusers. This study aimed to identify risk factors that were associated with rhabdomyolysis in cough medicine abusers.
Ka Chun Lam, Shan Liu, Chun Fai Hui
doaj   +1 more source

Safety and tolerance of oral dextromethorphan in patients at risk for brain ischemia.

, 1991
Experimental ischemia models have shown the antitussive dextromethorphan to be an N-methyl-D-aspartate antagonist with neuroprotective properties.
G W Albers, J A Moses, R E Sáenz, D W Choi   +3 more
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The CYP2D6 phenotyping performance of single-point saliva metabolic ratio in a healthy Chinese Han population

Frontiers in Pharmacology
The CYP2D6 plays critical roles in drug metabolism, and its inter-individual variability should be properly addressed in clinical practice. Our research aimed to assess the performance of single-point saliva metabolic ratio (MR) in a healthy Chinese Han ...
Yongfa Huang, Yongfa Huang, Yongfa Huang, Zhangyuting He, Zhangyuting He, Xiaoduo Guan, Pei Hu, Rui Chen   +7 more
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Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment

, 2011
Item does not contain fulltextPURPOSE: Tamoxifen, a widely used agent for the prevention and treatment of breast cancer, is mainly metabolized by CYP2D6 and CYP3A to form its most abundant active metabolite, endoxifen.
Seynaeve, C., Mathijssen, R.H., Van Der Holt, Bronno; id_orcid, Jaap Verweij, Mathijssen, Ron H.J., Aad I. de Vos, Beijnen, Jos H., Jongh, F.E. de, Robbert J. van Alphen, De Vos, Aad I., Verweij, J., Sebastiaan F. Teunissen, Vos, F.Y. de, Mathijssen, Ron H.J.; id_orcid, Jos H. Beijnen, Teunissen, S.F., Van Alphen, Robbert J., Loos, W.J., Holt, B. van der, Alphen, R.J. van, Walter J. Loos, Bronno van der Holt, De Graan, Anne Joy M., Anne-Joy M. de Graan, Teunissen, Sebastiaan F., Filip Y.F.L. de Vos, Felix E. de Jongh, De Jongh, Felix E., Vos, A.I. de, Beijnen, J.H., De Vos, Filip Y.F.L., Verweij, Jaap, Seynaeve, Caroline, Ron H.N. van Schaik, Ron H.J. Mathijssen, Loos, Walter J., Van Schaik, Ron H.N., Schaik, R.H. van, Caroline Seynaeve, Graan, A.J. de, Van Der Holt, Bronno   +40 more
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The evaluation of role of NMDA receptor and spinal microglia on age dependent differences of neuropathic pain in SNL model in male rats

Iranian South Medical Journal, 2015
Background: Induced neuropathic pain following nerve injury has behavioral signs such as allodynia and hyperalgesia. There are reports about the age dependent differences in severity and incidence and even therapeutic response of this pain. In this study,
Hussain zeinali, Homa Shardi-Manaheji, Samad Nazemi, Mehdi sadeghi   +3 more
doaj  

Clinical Toxicology of OTC Cough and Cold Pediatric Medications: A Narrative Review

Pediatric Health, Medicine and Therapeutics
Ajeng Diantini,1,2,* Mohammed Alfaqeeh,3,* Lanny Indah Permatasari,3,* Mirna Nurfitriani,3,* Lela Durotulailah,3,* Wening Wulandari,3,* Truly Deti Rose Sitorus,4 Gofarana Wilar,1,2 Jutti Levita1,2,* 1Department of Pharmacology
Diantini A, Alfaqeeh M, Permatasari LI, Nurfitriani M, Durotulailah L, Wulandari W, Sitorus TDR, Wilar G, Levita J   +8 more
doaj  

Effects of Dextromethorphan on Depressive- and Cognitive-Associated Behaviors: A Sexually Dimorphic Study

Basic and Clinical Neuroscience, 2019
Introduction: We investigated the sexually dimorphic effects of Dextromethorphan (DM) on cognitive and depression-like behaviors as well as on hippocampal histology in rats following acute administration.
Omamuyovwi Meashack Ijomone, Ifechukwude Joachim Biose   +1 more
doaj  

Dextromethorphan [PDF]

, 2020
openaire   +1 more source