Results 71 to 80 of about 9,214 (193)

Potential Negative Effects of Dextromethorphan as an Add-On Therapy to Methylphenidate in Children With ADHD

Frontiers in Psychiatry, 2019
Objectives: Methylphenidate (MPH) is highly effective in controlling the symptoms of attention-deficit/hyperactivity disorder (ADHD), but some children with ADHD either do not respond to, or do not tolerate, treatment.
Wei-Chen Chuang, Wei-Chen Chuang, Chin-Bin Yeh, Sheng-Chiang Wang, Sheng-Chiang Wang, Pei-Yin Pan, Jia-Fwu Shyu, Jia-Fwu Shyu, Yia-Ping Liu, Yia-Ping Liu, Susan Shur-Fen Gau, Ru-Band Lu, Ru-Band Lu, Ru-Band Lu   +13 more
doaj   +1 more source

Randomized open-label trial of dextromethorphan in Rett syndrome

, 2017
Objective:To determine safety and perform a preliminary assessment of dose-dependent efficacy of dextromethorphan in normalizing electrographic spikes, clinical seizures, and behavioral and cognitive functions in girls with Rett syndrome.Methods:We used ...
Gayane Yenokyan, Siddharth Gupta, Nga Brereton, Abanti Sanyal, Joshua B. Ewen, Manisha Hong, Genila Bibat, Sakkubai Naidu, Lisa Kratz, Michael V. Johnston, Constance L. Smith-Hicks, Elaine Tierney, Richard Kelley, Rebecca Vaurio   +13 more
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Acute generalized exanthematous pustulosis due to dextromethorphan [PDF]

, 2013
Acute generalized exanthematous pustulosis (AGEP) is a rare, severe, pustular, cutaneous reaction. We report a case in which a patient developed AGEP after the intake of 3 different antitussive agents containing dextromethorphan as the only ingredient in
Perez Paredes, G., Rodriguez Prieto, M.A., Otero Rivas, M.M., Sanchez Sambucety, P., Garcia-Ruiz de Morales, J.M.   +4 more
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Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia

پزشکی بالینی ابن سینا, 2009
Introduction & Objective: Postoperative pain has harmful effects in many systems. Dextromethorphan reduces postoperative pain in post partum tubal ligation under general anesthesia.
Nahid Manochehrian, Seyyed Majid Hashemi Fesharaki, Pooran Hajian, Ebrahim Khoshraftar   +3 more
doaj  

Deuteration may reduce the efficacy of dextromethorphan in treating agitation in Alzheimer’s disease

Alzheimer’s Research & Therapy
Agitation is one of the most prevalent neuropsychiatric symptoms leading to institutionalization in individuals with Alzheimer’s disease (AD) dementia.
Anton Bespalov, Jina Swartz, Nadine Knowles, Hans J. Moebius   +3 more
doaj   +1 more source

Neurons in the hippocampal CA1 region, but not the dentate gyrus, are susceptible to oxidative stress in rats with streptozotocin-induced type 1 diabetes

Neural Regeneration Research, 2015
In this study, we investigated the effects of streptozotocin-induced type 1 diabetes on antioxidant-like protein-1 immunoreactivity, protein carbonyl levels, and malondialdehyde formation, a marker for lipid peroxidation, in the hippocampus.
Sang Gun Lee, Dae Young Yoo, Hyo Young Jung, Sung Min Nam, Jong Whi Kim, Jung Hoon Choi, Sun Shin Yi, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwang, Seung Myung Moon   +10 more
doaj   +1 more source

Dextromethorphan and bupropion reduces high level remifentanil self-administration in rats.

, 2020
Opiate addiction has risen substantially during the past decade. New treatments to combat opiate addiction are sorely needed. The current study was conducted to determine the acute individual and interactive effects of bupropion and dextromethorphan in a
Levin, Edward D, Wells, Corinne, Modarres, John, Blair, Graham, Rezvani, Amir H, Rose, Jed E, Pace, Caroline, Ko, Ashley, Davis, James M   +8 more
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Concomitant use of dextromethorphan and alcohol‐induced dissociation in a patient with alcohol dependence

PCN Reports
Background Dextromethorphan (DXM) is an over‐the‐counter drug that is commonly abused by teenagers. Its main pharmacological property is a low‐affinity N‐methyl‐d‐aspartate (NMDA) receptor antagonist.
Yasuhito Nagai, Yuko Tajima, Koichi Miyakawa   +2 more
doaj   +1 more source

Protective effects of dextromethorphan and tizanidine on ouabain-induced arrhythmias

, 2002
The effects of the opioid agonist dextromethorphan and the alpha(2)-adrenoceptor agonist tizanidine on ouabain-induced cardiac arrhythmias were investigated in rats.
Sevgi, S., Oezek, M., Ozek, Mehmet, Sevgi, S, Ueresin, Y., Uresin, Y   +5 more
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A case series of dextromethorphan abuse

, 2018
Dextromethorphan, an over the counter cough suppressant is gaining popularity among teenagers and young adults because of its easy availability, relatively low price and most importantly the feeling good effects that it brought when used in megadoses. We
Nur Asiha Binti Sazali 2
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