Results 71 to 80 of about 9,444 (165)

Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment

, 2011
Item does not contain fulltextPURPOSE: Tamoxifen, a widely used agent for the prevention and treatment of breast cancer, is mainly metabolized by CYP2D6 and CYP3A to form its most abundant active metabolite, endoxifen.
Seynaeve, C., Mathijssen, R.H., Van Der Holt, Bronno; id_orcid, Jaap Verweij, Aad I. de Vos, Beijnen, Jos H., Jongh, F.E. de, Robbert J. van Alphen, De Vos, Aad I., Verweij, J., Sebastiaan F. Teunissen, Vos, F.Y. de, Mathijssen, Ron H.J.; id_orcid, Jos H. Beijnen, Teunissen, S.F., Van Alphen, Robbert J., Loos, W.J., Holt, B. van der, Alphen, R.J. van, Walter J. Loos, Bronno van der Holt, De Graan, Anne Joy M., Anne-Joy M. de Graan, Teunissen, Sebastiaan F., Filip Y.F.L. de Vos, Felix E. de Jongh, De Jongh, Felix E., Vos, A.I. de, Beijnen, J.H., De Vos, Filip Y.F.L., Verweij, Jaap, Seynaeve, Caroline, Ron H.N. van Schaik, Ron H.J. Mathijssen, Loos, Walter J., Van Schaik, Ron H.N., Schaik, R.H. van, Caroline Seynaeve, Graan, A.J. de   +38 more
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Analgesic effects of dextromethorphan and morphine in patients with chronic pain

, 2002
N-methyl-aspartate (NMDA) receptor antagonists have been shown to improve opioid analgesia in the animal model. The cough suppressant dextromethorphan is a clinically available NMDA-receptor antagonist.
Kalso, E,, Heiskanen, T, Dahl, M-L, Härtel, B, Seppälä, T   +4 more
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Dextromethorphan protects against cerebral injury following transient focal ischemia in rabbits.

, 1988
We investigated dextromethorphan, both a dextrorotatory opioid derivative and a clinically tested N-methyl-D-aspartate (NMDA) receptor antagonist, in a rabbit model of transient focal cerebral ischemia.
G K Steinberg, C P George, R DeLaPaz, T Gross, D K Shibata   +4 more
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Comparison of patients with benzodiazepine receptor agonist‐related psychiatric disorders and over‐the‐counter drug‐related psychiatric disorders before and after the COVID‐19 pandemic: Changes in psychosocial characteristics and types of abused drugs

Neuropsychopharmacology Reports
Aim To investigate changes in the clinical characteristics of patients who abused benzodiazepine receptor agonists (BZRA) or over‐the‐counter (OTC) drugs before and after COVID‐19 based on the 2018 and 2022 data of the “Nationwide Psychiatric Hospital ...
Takashi Usami, Kyoji Okita, Takuya Shimane, Toshihiko Matsumoto   +3 more
doaj   +1 more source

NMR studies of dextromethorphan in both isotropic and anisotropic states

, 2010
NMR studies of dextromethorphan in both isotropic and anisotropic ...
Trent Ashton (13097196), J Swarbrick (13734484)   +1 more
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To the Editors:

, 2014
A wide range of drugs is being abused by teenagers across the world, and over the years, they seem to have made the discovery that they could get "high " by taking over-the-counter medicines containing dextromethorphan (DXM).
Dextromethorphan Abuse
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Dextromethorphan Bupropion Combination Tablet Suicide Attempt by Overdose: A Case Report

Neuropsychopharmacology Reports
Dextromethorphan and bupropion in combination are approved to treat major depressive disorders in adults. This case report describes a patient with a history of treatment‐resistant depression who presented to the emergency department after overdosing on ...
Daniel Greer, Justina Girgis, John Kashani, Jennifer Atherton   +3 more
doaj   +1 more source

Determination of Dextromethorphan and Dextrorphan in Urine Using Bar Adsorptive Microextraction Followed by Gas Chromatography–Mass Spectrometry Analysis

Separations
Over the past few years, the misuse of medications has progressively increased, posing a significant public health concern. This study proposed the development and validation of an alternative and greener analytical method for the determination of ...
Marisa H. Maria, Margarida Fonseca, Alexandre Quintas, Nuno R. Neng   +3 more
doaj   +1 more source

Dextromethorphan [PDF]

Reactions Weekly, 2019
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Attenuation of the antidepressant-like effects of dextromethorphan, but not imipramine, by σ₁ receptor antagonism.

, 2014
Pretreatment with the σ1 receptor antagonist BD1063 (10 mg/kg, i.p.) prevented the dextromethorphan (30 mg/kg, i.p.)-induced decrease in immobility time (A).
Anna L. Scandinaro (529242), Jason R. Healy (529241), Linda Nguyen (195959), Rae R. Matsumoto (529243), Matthew J. Robson (529240)   +4 more
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