Results 51 to 60 of about 9,444 (165)

Antidepressant-like effects of imipramine and dextromethorphan in the forced swim test in mice.

, 2014
Imipramine (0–20 mg/kg, i.p.) significantly decreased immobility time (A), but had no significant effects on locomotor activity (B). Dextromethorphan (0–30 mg/kg, i.p.) significantly decreased immobility time (C), and significantly increased locomotor ...
Anna L. Scandinaro (529242), Jason R. Healy (529241), Linda Nguyen (195959), Rae R. Matsumoto (529243), Matthew J. Robson (529240)   +4 more
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Omission of the deconjugation step in urine analysis and the unaltered outcome of CYP2D6 phenotyping with dextromethorphan

, 1998
The present study was aimed at determining whether the deconjugation step in chemical analysis could be omitted without altering the outcome of phenotyping CYP2D6 with dextromethorphan.
A. Bozkurt, Kayaalp, SO, S. O. Kayaalp, A. Sayal, Sayal, A, N. E. Basci, A. Isimer, Bozkurt, A, Basci, NURSABAH ELİF, Isimer, A   +9 more
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Efficacy of Combined Dextromethorphan and Gabapentin as Premedication on Postoperative Pain Management in Knee Arthroscopy: A Clinical Trial

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Postoperative pain management would result in increased patient’s satisfaction and decreases their problems. This survey was performed to determine the efficacy of premedication with dextromethorphan and gabapentin alone or in ...
Said Reza Entezari, Pooya Derakhshan, Arezou Darvishi, Mahmoudreza Alebouyeh   +3 more
doaj  

Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice [PDF]

The main aim of this study was to evaluate the effects of dextromethorphan and midazolam and their combination on morphine tolerance and dependence in mice.
حبیبی اصل, بهلول, حسن زاده, کامبیز, خضری, اسماعیل, محمدی, پرهام سعداله   +3 more
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Cold Pain Threshold and Role of NMDA Receptor Antagonists

Acta Medica Iranica, 2019
Clonidine, the α2-adrenergic agonist, is usually used as an antihypertensive drug. Dextromethorphan is a non-competitive NMDA antagonist which is routinely prescribed to suppress cough.
Poroshat Nazemi, Amir Hossein Orandi, Amir Ali Orandi, Amir Poya Zanjani, Hossein Majedi, Mojgan Rahimi, Kasra Karvandian, Fardin Yousefshahi, Atieh Sedighian, Seyed Ali Emami   +9 more
doaj  

Effects of dextromethorphan on dopamine dependent behaviours in rats

, 2007
712-719Dextromethorphan, a noncompetitive blocker of N-methyl-D- aspartate (NMDA) type of glutamate receptor, at 7.5-75 mg/kg, ip did not induce oral stereotypies or catalepsy and did not antagonize apomorphine stereotypy in rats.
Jadhav, J H, Thorat, V M, Gaikwad, R V, Jadhav, S A, Gaonkar, R K, Balsara, J J   +5 more
core  

Dextromethorphan and mephenytoin phenotyping of patients treated with thioridazine or amitriptyline.

, 1992
The metabolism of most tricyclic antidepressants and some phenothiazine neuroleptics is under the genetic control of hepatic cytochrome P-450IID6, which also regulates the metabolism of dextromethorphan.
Jonzier-Perey, M., Baettig, D., Baumann, P., Koeb, L., Monney, C., Meyer, J.W., Amey, M., Bryois, C., Woggon, B.   +8 more
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Efficacy of Premedication with Oral Dextromethorphan and Ibuprofen for Pain Relief After Root Canal Therapy in Patients with Irreversible Pulpitis

Journal of Islamic Dental Association of Iran, 2016
Background and Aim: Researchers have been in search of medications with less side effects to relieve pain after root canal therapy. This study aimed to assess the efficacy of premedication with oral dextromethorphan and Ibuprofen to decrease pain after ...
Maryam Zare Jahromi, Elmira Ahmadpour
doaj  

Dextromethorphan abuse [PDF]

Canadian Medical Association Journal, 2014
Tony, Antoniou, David N, Juurlink
openaire   +2 more sources

Dextromethorphan inhibits 5-hydroxytryptamine uptake by human blood platelets and decreases 5-hydroxyindoleacetic acid content in rat brain

, 1975
The effect of dextromethorphan on the uptake and metabolism of 5-hydroxytryptamine (5-HT) was studied in human blood platelets and in rat brain. In the concentration of 120 nM dextromethorphan inhibited the uptake of 5-HT (1 μM) into platelets by 50 ...
Liisa Ahtee
core   +1 more source