Results 31 to 40 of about 9,444 (165)

Effect of a single dose of dextromethorphan on psychomotor performance and working memory capacity

Indian Journal of Psychological Medicine, 2012
Background: Previous studies show that the prolonged use of dextromethorphan produces cognitive deterioration in humans. Aim: The aim of this study was to investigate the effect of a single dose of dextroemthrophan on psychomotor performance and working ...
Hayder M Al-Kuraishy, Ali I Al-Gareeb, Ammar Waham Ashor   +2 more
doaj   +1 more source

Sub-cellular sequestration of alkaline drugs in lysosomes: new insights for pharmaceutical development of lysosomal fluid

Research in Pharmaceutical Sciences, 2023
Background and purpose: Lysosomal-targeted drug delivery can open a new strategy for drug therapy. However, there is currently no universally accepted simulated or artificial lysosomal fluid utilized in the pharmaceutical industry or recognized by the ...
Malaz Yousef, Tyson S Le, Jieyu Zuo, Chulhun Park, Nadia Bou Chacra, Neal M Davies, Raimar Löbenberg   +6 more
doaj   +1 more source

Characteristics of dextromethorphan-bupropion exposures compared with exposures involving dextromethorphan alone or bupropion alone reported to United States poison centers

Toxicology Communications
Background Despite concerns regarding toxicity of the novel antidepressant, dextromethorphan-bupropion (DXM-BUP) in overdose, there is little information available.
Sonia Ngo, Natalie I. Rine, Sandhya Kistamgari, Gary A. Smith, Hannah L. Hays   +4 more
doaj   +1 more source

Identification and in vivo Efficacy Assessment of Approved Orally Bioavailable Human Host Protein-Targeting Drugs With Broad Anti-influenza A Activity

Frontiers in Immunology, 2019
The high genetic variability of influenza A viruses poses a continual challenge to seasonal and pandemic vaccine development, leaving antiviral drugs as the first line of defense against antigenically different strains or new subtypes.
Theresa Enkirch, Theresa Enkirch, Svenja Sauber, Danielle E. Anderson, Esther S. Gan, Dimitar Kenanov, Sebastian Maurer-Stroh, Sebastian Maurer-Stroh, Veronika von Messling, Veronika von Messling   +9 more
doaj   +1 more source

AMBER trial (amla-based extract for endobronchial ultrasound cough reduction): A randomized controlled study

Complementary Therapies in Medicine
Background: Cough during endobronchial ultrasound (EBUS) is common and can reduce patient comfort, prolong procedures, and compromise diagnostic yield. While dextromethorphan has demonstrated antitussive efficacy, concerns remain regarding side effects ...
Wanvisa Boonfueang, Chatuthanai Savigamin, Vorawut Thanthitaweewat, Nophol Leelayuwatanakul, Virisorn Wongsrichanalai, Kamon Kawkitinarong, Chanchai Sittipunt, Amornpun Wongkarnjana, Monvasi Pachinburavan, Thitiwat Sriprasart   +9 more
doaj   +1 more source

Antitussive Activity of Herbal Cough Medicine on Guinea Pigs (Cavia porvellus)

Majalah Obat Tradisional, 2021
This study aims to investigate the antitussive activity of herbal cough medicine containing combined herbal extracts of Echinacea purpurea, Sambucus nigra (Black Elderberry), Glycyrrhiza glabra (licorice), Vitex trifolia (Indian wild pepper), and ...
Zullies Ikawati, Poppy Firzani Arifin, Severinus Nugraha Krisma Sandy, Raphael Aswin Susilowidodo, Rosalina Wisastra   +4 more
doaj   +1 more source

Dextromethorphan/Quinidine

Drugs in R & D, 2005
Avanir Pharmaceuticals in the US is developing a fixed-dose combination of dextromethorphan (30 mg), a weak NMDA antagonist/sigma 1 agonist, and quinidine (30 mg), a cytochrome P450-2D6 (CYP2D6) enzyme inhibitor [AVP 923, Neurodextrade mark]. Quinidine sustains therapeutic levels of dextromethorphan over a 12-hour dosing schedule by inhibiting ...
openaire   +2 more sources

Effect of Dextromethorphan on the neuromuscular transmission of the chick biventer cervicis muscle preparation

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2003
Background and Objective: Dextromethorphan is a well-known over-the-counter antitussive drug with over 45 years of clinical usage experience.
D Farzin, M Zavareh
doaj  

Dextromethorphan Role on Cough Suppression and Patient Procedure Tolerance in Flexible Bronchoscopy

Pakistan Armed Forces Medical Journal
  Objective: To determine the role of Dextromethorphan on cough suppression and patient procedure tolerance in flexible bronchoscopy. Study Design: Quasi-experimental study.
Mehvish Aqil, Mehr Muhammad Imran, Umar Usman, Saqib Musharaf, Zaheer Ahmed, Ali Hamad   +5 more
doaj   +1 more source

Repetitive dextromethorphan at adolescence affects water maze learning in female rats

, 2006
Effects of repetitive dextromethorphan at adolescence on a spatial learning of rats were investigated. Rats received 10 daily injections of dextromethorphan (40 mg/kg) from postnatal day 28 thru 37, and were then subjected to the Morris water maze task ...
조희정, 이서울, 장정원, 이주영   +3 more
core   +1 more source