Results 61 to 70 of about 13,931 (178)

Characteristics of drug and dietary supplement inquiries by college athletes. [PDF]

open access: yes, 2010
BackgroundIn the United States, the National Center for Drug Free Sport manages the drug-testing programs for athletes of the National Collegiate Athletic Association (NCAA).
Ambrose, Peter J   +3 more
core   +1 more source

Unspecific Peroxygenases‐Catalyzed Oxidation of Pharmaceutical Compounds Considered Emerging Contaminants

open access: yesChemBioChem, Volume 27, Issue 8, April 2026.
PaDa‐I and JaWa, two evolved UPO variants, catalyze the oxidation of 9 out of 12 pharmaceutical emerging contaminants, with TTN up to 4500. The enzymes exhibit distinct substrate selectivity. Only PaDa‐I can catalyze the simultaneous oxidation of substrates in wastewater samples.
Alina Torres‐Aguirre   +4 more
wiley   +1 more source

Visual bone marrow mesenchymal stem cell transplantation in the repair of spinal cord injury

open access: yesNeural Regeneration Research, 2015
An important factor in improving functional recovery from spinal cord injury using stem cells is maximizing the number of transplanted cells at the lesion site.
Rui-ping Zhang   +4 more
doaj   +1 more source

Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes [PDF]

open access: yes, 2016
Cytochrome p450 (CYP450) enzymes are predominantly involved in Phase I metabolism of xenobiotics. In this study, the CYP450 isoforms involved in xanthotoxol metabolism were identified using recombinant CYP450s.
Cai, Jiqun   +5 more
core   +5 more sources

Over-the-counter medications for acute cough in children and adults in ambulatory settings. [PDF]

open access: yes, 2008
BACKGROUND: Acute cough due to upper respiratory tract infection (URTI) is a common symptom. Non-prescription over-the-counter (OTC) medicines are frequently recommended as a first-line treatment, but there is little evidence as to whether these drugs ...
Fahey, Tom   +2 more
core   +1 more source

Codeine versus placebo for chronic cough in children (Review) [PDF]

open access: yes, 2016
Background: Cough in children is a commonly experienced symptom that is associated with increased health service utilisation and burden to parents.
Chang, Anne B.   +3 more
core   +1 more source

What drives progressive motor deficits in patients with acute pontine infarction?

open access: yesNeural Regeneration Research, 2015
Progressive motor deficits are relatively common in acute pontine infarction and frequently associated with increased functional disability. However, the factors that affect the progression of clinical motor weakness are largely unknown. Previous studies
Jue-bao Li   +6 more
doaj   +1 more source

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

open access: yesDrug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu   +7 more
wiley   +1 more source

Polymorphic drug metabolising enzymes:Assessment of activities by phenotyping and genotyping in clinical pharmacology [PDF]

open access: yes, 2001
Drug effects (pharmacodynamics) are determined by drug concentration at target site and the affinity of the drug for a target. Pharmacogenetics describes inherited differences in drug metabolising enzyme activities and differences in drug transporters ...
Tamminga, Willem Jan
core   +2 more sources

Investigating Emotional Reactivity in Experienced Users of Psychedelics: A Cross‐Sectional fMRI Study

open access: yesHuman Brain Mapping, Volume 47, Issue 5, 1 April 2026.
This cross‐sectional fMRI study compared experienced psychedelic users and matched nonusers on behavioral and neural responses to emotional facial expressions. Findings reveal neurofunctional differences between groups in emotional reactivity, highlighting both similarities and important distinctions in the long‐term effects of naturalistic versus ...
Paweł Orłowski   +2 more
wiley   +1 more source

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