Results 61 to 70 of about 9,444 (165)

Acute generalized exanthematous pustulosis due to dextromethorphan [PDF]

, 2013
Acute generalized exanthematous pustulosis (AGEP) is a rare, severe, pustular, cutaneous reaction. We report a case in which a patient developed AGEP after the intake of 3 different antitussive agents containing dextromethorphan as the only ingredient in
Perez Paredes, G., Rodriguez Prieto, M.A., Otero Rivas, M.M., Sanchez Sambucety, P., Garcia-Ruiz de Morales, J.M., Otero Rivas, M.M. ; Sanchez Sambucety, P. ; Garcia-Ruiz de Morales, J.M. ; Perez Paredes, G. ; Rodriguez Prieto, M.A., P. Sanchez Sambucety, G. Perez Paredes, M.M. Otero Rivas, J.M. Garcia-Ruiz de Morales, M.A. Rodriguez Prieto   +10 more
core   +1 more source

Neuroprotective effects of SMADs in a rat model of cerebral ischemia/reperfusion

Neural Regeneration Research, 2015
Previous studies have shown that up-regulation of transforming growth factor β1 results in neuroprotective effects. However, the role of the transforming growth factor β1 downstream molecule, SMAD2/3, following ischemia/reperfusion remains unclear. Here,
Fang-fang Liu, Chao-ying Liu, Xiao-ping Li, Sheng-zhe Zheng, Qing-quan Li, Qun Liu, Lei Song   +6 more
doaj   +1 more source

Dextromethorphan prevents the diethyldithiocarbamate enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice

, 2003
In this report we show that dextromethorphan, a non-opioid cough suppressant, prevents the neurodegeneration of dopaminergic neurons in the substantia nigra of mice treated with diethyldithiocarbamate (DDC) and 1-methyl-4-phenyl-1,2,3,6 ...
BONUCCELLI, UBALDO, CORSINI, GIOVANNI UMBERTO, MAGGIO R, VAGLINI, FRANCESCA, PARDINI, CARLA MARIA FRANCESCA, PARDINI C, VAGLINI F, CORSINI GU, MAGGIO, Roberto   +8 more
core   +1 more source

A case series of dextromethorphan abuse

, 2018
Dextromethorphan, an over the counter cough suppressant is gaining popularity among teenagers and young adults because of its easy availability, relatively low price and most importantly the feeling good effects that it brought when used in megadoses. We
Nur Asiha Binti Sazali 2
core  

Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia

پزشکی بالینی ابن سینا, 2009
Introduction & Objective: Postoperative pain has harmful effects in many systems. Dextromethorphan reduces postoperative pain in post partum tubal ligation under general anesthesia.
Nahid Manochehrian, Seyyed Majid Hashemi Fesharaki, Pooran Hajian, Ebrahim Khoshraftar   +3 more
doaj  

Deuteration may reduce the efficacy of dextromethorphan in treating agitation in Alzheimer’s disease

Alzheimer’s Research & Therapy
Agitation is one of the most prevalent neuropsychiatric symptoms leading to institutionalization in individuals with Alzheimer’s disease (AD) dementia.
Anton Bespalov, Jina Swartz, Nadine Knowles, Hans J. Moebius   +3 more
doaj   +1 more source

Potential Negative Effects of Dextromethorphan as an Add-On Therapy to Methylphenidate in Children With ADHD

Frontiers in Psychiatry, 2019
Objectives: Methylphenidate (MPH) is highly effective in controlling the symptoms of attention-deficit/hyperactivity disorder (ADHD), but some children with ADHD either do not respond to, or do not tolerate, treatment.
Wei-Chen Chuang, Wei-Chen Chuang, Chin-Bin Yeh, Sheng-Chiang Wang, Sheng-Chiang Wang, Pei-Yin Pan, Jia-Fwu Shyu, Jia-Fwu Shyu, Yia-Ping Liu, Yia-Ping Liu, Susan Shur-Fen Gau, Ru-Band Lu, Ru-Band Lu, Ru-Band Lu   +13 more
doaj   +1 more source

Concomitant use of dextromethorphan and alcohol‐induced dissociation in a patient with alcohol dependence

PCN Reports
Background Dextromethorphan (DXM) is an over‐the‐counter drug that is commonly abused by teenagers. Its main pharmacological property is a low‐affinity N‐methyl‐d‐aspartate (NMDA) receptor antagonist.
Yasuhito Nagai, Yuko Tajima, Koichi Miyakawa   +2 more
doaj   +1 more source

Neurons in the hippocampal CA1 region, but not the dentate gyrus, are susceptible to oxidative stress in rats with streptozotocin-induced type 1 diabetes

Neural Regeneration Research, 2015
In this study, we investigated the effects of streptozotocin-induced type 1 diabetes on antioxidant-like protein-1 immunoreactivity, protein carbonyl levels, and malondialdehyde formation, a marker for lipid peroxidation, in the hippocampus.
Sang Gun Lee, Dae Young Yoo, Hyo Young Jung, Sung Min Nam, Jong Whi Kim, Jung Hoon Choi, Sun Shin Yi, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwang, Seung Myung Moon   +10 more
doaj   +1 more source

Awareness and practices of community pharmacists toward dextromethorphan misuse in Jeddah, Saudi Arabia: implications for regulation and public health

Frontiers in Medicine
BackgroundDextromethorphan (DXM) is an over-the-counter cough suppressant with recognized potential for misuse and abuse when taken at supratherapeutic doses. Community pharmacists are well positioned to identify and prevent such misuse, yet limited data
Aisha T. Alnami, Aisha T. Alnami, Anfal S. Aljahdali, Haifa M. Alqahtani, Maha M. Khayat, Amal J. Aloshayni, Manal M. Aleesi, Mohammed M. Aldurdunji   +7 more
doaj   +1 more source