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Dextromethorphan - Molecule of the Month February 2024 [Archived version]

This is the Molecule of the Month entry for February 2024 about dextromethorphan. It is a pdf archive version of the HTML webpage.
Paul May (4181839)
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Risk factors of developing rhabdomyolysis in cough medicine abusers presented to the accident and emergency departments in Hong Kong during 2008–2023

Hong Kong Journal of Emergency Medicine
Introduction Rhabdomyolysis was observed in cough medicine abusers. This study aimed to identify risk factors that were associated with rhabdomyolysis in cough medicine abusers.
Ka Chun Lam, Shan Liu, Chun Fai Hui
doaj   +1 more source

Effects of dextromethorphan on rat brain during ischemia and reperfusion assessed by magnetic resonance spectroscopy.

, 1991
Using proton and phosphorus magnetic resonance spectroscopy, we evaluated the metabolic effects of preischemic administration of the N-methyl-D-aspartate antagonist dextromethorphan (50 mg/kg i.p.) during global forebrain ischemia and subsequent ...
C J van Echteld, M M Nasim, H B Verheul, P Lewis, P C van Rijen, R Balázs, C A Tulleken   +6 more
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The evaluation of role of NMDA receptor and spinal microglia on age dependent differences of neuropathic pain in SNL model in male rats

Iranian South Medical Journal, 2015
Background: Induced neuropathic pain following nerve injury has behavioral signs such as allodynia and hyperalgesia. There are reports about the age dependent differences in severity and incidence and even therapeutic response of this pain. In this study,
Hussain zeinali, Homa Shardi-Manaheji, Samad Nazemi, Mehdi sadeghi   +3 more
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DETERMINATION OF DEXTROMETHORPHAN AND DIMEMORPHAN IN BODY FLUIDS BY GAS CHROMATOGRAPHY WITH SURFACE IONIZATION DETECTION [PDF]

Dextromethorphan and dimemorphan were found detectable with high sensitivity by gas chromatography with surface ionization detection. Dextromethorphan was measured against dimemorphan as internal standard, and dimemorphan measured against ...
Seno, Hiroshi, Iizumi, Takumi, Hattori, Hideki, Suzuki, Osamu, Kumazawa, Takeshi   +4 more
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Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats

, 2005
620-625Dextromethorphan, a noncompetitive blocker of the N-methyl-D-aspartate (NMDA) type of glutamate receptor, at 45, 60 and 75 mg/kg, ip doses induced a behavioural syndrome characterised by reciprocal forepaw treading, lateral head-weaving, hind ...
Jadhav, J H, Thorat, V M, Gaikwad, R V, Jadhav, S A, Gaonkar, R K, Balsara, J J   +5 more
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Clinical Toxicology of OTC Cough and Cold Pediatric Medications: A Narrative Review

Pediatric Health, Medicine and Therapeutics
Ajeng Diantini,1,2,* Mohammed Alfaqeeh,3,* Lanny Indah Permatasari,3,* Mirna Nurfitriani,3,* Lela Durotulailah,3,* Wening Wulandari,3,* Truly Deti Rose Sitorus,4 Gofarana Wilar,1,2 Jutti Levita1,2,* 1Department of Pharmacology
Diantini A, Alfaqeeh M, Permatasari LI, Nurfitriani M, Durotulailah L, Wulandari W, Sitorus TDR, Wilar G, Levita J   +8 more
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Applicability of continuous-flow fast atom bombardment liquid chromatography-mass spectrometry in bioanalysis. Dextromethorphan in plasma

, 1989
Continuous-flow fast atom bombardment (CF-FAB) is an interface for combined liquid chromatography-mass spectrometry using FAB as the ionization method.
Greef, J. van der, Kokkonen, P., Tjaden, U.R., Niessen, W.M.A.   +3 more
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Effects of Dextromethorphan on Depressive- and Cognitive-Associated Behaviors: A Sexually Dimorphic Study

Basic and Clinical Neuroscience, 2019
Introduction: We investigated the sexually dimorphic effects of Dextromethorphan (DM) on cognitive and depression-like behaviors as well as on hippocampal histology in rats following acute administration.
Omamuyovwi Meashack Ijomone, Ifechukwude Joachim Biose   +1 more
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Dextromethorphan [PDF]

, 2020
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