Results 81 to 90 of about 9,214 (193)

Effects of dextromethorphan on nocturnal behavior and brain c-Fos expression in adolescent rats

, 2001
Dextromethorphan, an antitussive widely available over-the-counter, is abused, mostly by teenagers at high doses. In our previous report, a high dose of dextromethorphan activated the midbrain dopamine neurons of adolescent rats. In the present study, we
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Awareness and practices of community pharmacists toward dextromethorphan misuse in Jeddah, Saudi Arabia: implications for regulation and public health

Frontiers in Medicine
BackgroundDextromethorphan (DXM) is an over-the-counter cough suppressant with recognized potential for misuse and abuse when taken at supratherapeutic doses. Community pharmacists are well positioned to identify and prevent such misuse, yet limited data
Aisha T. Alnami, Aisha T. Alnami, Anfal S. Aljahdali, Haifa M. Alqahtani, Maha M. Khayat, Amal J. Aloshayni, Manal M. Aleesi, Mohammed M. Aldurdunji   +7 more
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Phenotypic Differences in Dextromethorphan Metabolism

, 1989
Polymorphic differences in dextromethorphan metabolism were observed in three studies conducted in a total of 44 subjects (of Dutch origin) administered 60 mg dextromethorphan hydrobromide as an OROS tablet.
de Zeeuw , R, Leeson, L.J, Braun, Richard L, Prasad, V.K, Jonkman, J.H.J, Cabana, Bernard E, de Zeeuw, R, Vetticaden, Santosh J, Purich, E.D, Ball, LuAnn   +9 more
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Repetitive dextromethorphan at adolescence affects water maze learning in female rats

, 2006
Effects of repetitive dextromethorphan at adolescence on a spatial learning of rats were investigated. Rats received 10 daily injections of dextromethorphan (40 mg/kg) from postnatal day 28 thru 37, and were then subjected to the Morris water maze task ...
조희정, 이서울, 장정원, 이주영   +3 more
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Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice [PDF]

The main aim of this study was to evaluate the effects of dextromethorphan and midazolam and their combination on morphine tolerance and dependence in mice.
حبیبی اصل, بهلول, حسن زاده, کامبیز, خضری, اسماعیل, محمدی, پرهام سعداله   +3 more
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Comparison of patients with benzodiazepine receptor agonist‐related psychiatric disorders and over‐the‐counter drug‐related psychiatric disorders before and after the COVID‐19 pandemic: Changes in psychosocial characteristics and types of abused drugs

Neuropsychopharmacology Reports
Aim To investigate changes in the clinical characteristics of patients who abused benzodiazepine receptor agonists (BZRA) or over‐the‐counter (OTC) drugs before and after COVID‐19 based on the 2018 and 2022 data of the “Nationwide Psychiatric Hospital ...
Takashi Usami, Kyoji Okita, Takuya Shimane, Toshihiko Matsumoto   +3 more
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Effects of dextromethorphan on dopamine dependent behaviours in rats

, 2007
712-719Dextromethorphan, a noncompetitive blocker of N-methyl-D- aspartate (NMDA) type of glutamate receptor, at 7.5-75 mg/kg, ip did not induce oral stereotypies or catalepsy and did not antagonize apomorphine stereotypy in rats.
Jadhav, J H, Thorat, V M, Gaikwad, R V, Jadhav, S A, Gaonkar, R K, Balsara, J J   +5 more
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Nonketotic hyperglycinemia: clinical and electrophysiologic effects of dextromethorphan, an antagonist of the NMDA receptor.

, 1993
A 10-week-old girl with nonketotic hyperglycinemia was treated with increasing amounts of dextromethorphan, an NMDA receptor antagonist. She improved neurologically; at 35 mg/kg/d, seizures ceased and EEG normalized.
Mascher H, Thun-Hohenstein L, Dumermuth G, Schmitt B, Gitzelmann R, Steinmann B   +5 more
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Dextromethorphan Bupropion Combination Tablet Suicide Attempt by Overdose: A Case Report

Neuropsychopharmacology Reports
Dextromethorphan and bupropion in combination are approved to treat major depressive disorders in adults. This case report describes a patient with a history of treatment‐resistant depression who presented to the emergency department after overdosing on ...
Daniel Greer, Justina Girgis, John Kashani, Jennifer Atherton   +3 more
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Dextromethorphan and mephenytoin phenotyping of patients treated with thioridazine or amitriptyline.

, 1992
The metabolism of most tricyclic antidepressants and some phenothiazine neuroleptics is under the genetic control of hepatic cytochrome P-450IID6, which also regulates the metabolism of dextromethorphan.
Jonzier-Perey, M., Baettig, D., Baumann, P., Koeb, L., Monney, C., Meyer, J.W., Amey, M., Bryois, C., Woggon, B.   +8 more
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