Results 101 to 110 of about 10,226 (209)
Studies on the Interaction of DGCR8 with the Cofactor Heme. [PDF]
, 2012 The RNA-binding protein DiGeorge Critical Region 8 (DGCR8) and its partner, the nuclease Drosha, are necessary for processing of primary microRNA (pri-miRNA) transcripts in animals.
Barr, Robert Ian
core
Correction to: Dgcr8 knockout approaches to understand microRNA functions in vitro and in vivo [PDF]
Cellular and Molecular Life Sciences, 2019 The section: "miRNA‑independent functions of DICER" was missed between the section "miRNA‑independent functions of DROSHA and DGCR8" and the section "The Dgcr8 knockout strategy to study miRNA functions" in the original publications.
Wen-Ting Guo, Yangming Wang
openaire +2 more sources
Regulation of HBEGF by Micro-RNA for Survival of Developing Human Trophoblast Cells. [PDF]
PLoS ONE, 2016 The growth factor HBEGF is upregulated post-transcriptionally in the low O2 environment of the human placenta during the first 10 weeks of pregnancy. We have examined the possible roles of HBEGF turnover and micro-RNA (miRNA) in its regulation by O2 in ...
Chandni V Jain +6 more
doaj +1 more source
RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets
MedComm, Volume 7, Issue 3, March 2026.RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin +9 more
wiley +1 more source
PLoS ONE, 2016 Severe radiation-induced toxicities limit treatment efficacy and compromise outcomes of lung cancer. We aimed to identify microRNA-related genetic variations as biomarkers for the prediction of radiotherapy-induced acute toxicities. We genotyped 233 SNPs
Rong Li +8 more
doaj +1 more source
How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle
Psychiatry and Clinical Neurosciences, Volume 80, Issue 3, Page 166-179, March 2026.Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang +3 more
wiley +1 more source
Candidate Dgcr8-independent miRNAs.
, 2012 Presented are the candidate Dgcr8-independent miRNAs alongside those identified as Dgcr8-independent by Babiarz et al.[25]. Included is the fold change of each miRNA seen in this study between heterozygous and Dgcr8-depleted cell lines (bold italics if ...
Cei Abreu-Goodger (10072) +10 more
core +1 more source
Protein & Cell, 2018 Primitive mammalian heart transforms from a single tube to a four-chambered muscular organ during a short developmental window. We found that knocking out global microRNA by deleting Dgcr8 microprocessor in Mesp1 cardiovascular progenitor cells lead to ...
Xi Chen +10 more
doaj +1 more source
The WHO Classification of Genetic Tumour Syndromes: Considerations for histopathology
Histopathology, Volume 88, Issue 7, Page 1291-1294, June 2026.
Ian A Cree +18 more
wiley +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, Volume 16, Issue 2, Page 299-313, February 2026.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source