Results 151 to 160 of about 10,226 (209)

It takes two to cleave: the logic of cluster assistance. [PDF]

Genes Dev
Sanborn O, Cifuentes D.
europepmc   +1 more source

Tracing the molecular route to progression in miRNA-biogenesis-defective thyroid lesions. [PDF]

JCI Insight
Chong AS, Roca C, Morales-Sánchez P, Dorca E, Barea V, Ruz-Caracuel I, Valderrabano P, Rovira C, Jou C, Bouron-Dal Soglio D, Chernock RD, Torrezan GT, Pusztaszeri M, Cameselle-Teijeiro JM, Matias-Guiu X, Alvarez CV, Salvador H, Wasserman JD, Leandro-García LJ, Foulkes WD, Andrés-León E, Casano-Sancho P, Rivera B.   +22 more
europepmc   +1 more source

Caspase-mediated cleavage of miRNA processing proteins Drosha, DGCR8, Dicer, and TRBP2 in heat-shocked cells and its inhibition by HSP70 overexpression

Cell stress & chaperones (Print), 2021
Lina Y. Abou Zeid, S. Shanmugapriya, Rebecca L. Rumney, D. Mosser   +3 more
semanticscholar   +1 more source

Toward understanding the structural basis of DGCR8 RNA-binding heme domain

, 2019
MicroRNAs (miRNAs) play an important role in the regulation of protein expression in eukaryotes. The initial step of producing pre-miRNAs from primary transcripts (pri-miRNAs) is processed by a Microprocessor consisting of a nuclease Drosha and its ...
Ha, Thi Thuy Hoa
core  

Nicotine promotes cardiac fibrosis by regulating miR-125b-5p maturation via HNRNPA2B1-mediated METTL14-dependent m⁶A methylation: therapeutic reversal by cinacalcet HCl. [PDF]

J Transl Med
Wu HH, Li YY, Meng FL, Du JM, Zheng Y, Song CH, Li LM, Li Y, Su GH.   +8 more
europepmc   +1 more source

Structural insights into disease-associated mutations in the microRNA processing machinery. [PDF]

Exp Mol Med
Lee H, Lee J, Roh SH.
europepmc   +1 more source

Neddylation-Mediated hnRNPA2B1 Degradation Aggravates Retinal Endothelial Cell Dysfunction in Diabetic Retinopathy by Regulating miR-93-5p/VEGFA. [PDF]

Invest Ophthalmol Vis Sci
Chen TR, Zhou JX, Hou YR, Zhang YN, Li CX, Zhu J, Guo ZR, Cui Y.   +7 more
europepmc   +1 more source

MicroRNA-425-3p: A Promising Biomarker and Candidate for Pharmacological Intervention in Neuropsychiatric Disabilities with Relevance to Major Depressive Disorder. [PDF]

Neuropsychiatr Dis Treat
May L, Dwivedi Y.
europepmc   +1 more source

EIF4A3-induced circUBAC2 promotes lung cancer progression via regulation of the Hippo signaling pathway. [PDF]

Cell Mol Biol Lett
Meng F, Zhang X, Wang X, Qiu B, Zeng D, Huang X, Liu J, Wu H, Cui K, Zhong B, Liu W, Gong X, He X.   +12 more
europepmc   +1 more source

METTL3 regulates Leydig cell proliferation via miR-145-PCK1 mediated gluconeogenesis in goats. [PDF]

J Anim Sci Biotechnol
Tang W, Cao M, Qiao F, Luo J, Ju Y, Wang X, An P, Sun W, Chen X.   +8 more
europepmc   +1 more source