Results 41 to 50 of about 37,693 (353)

Diabetic nephropathy

open access: yesDisease-a-Month, 1998
Diabetic nephropathy is the most common cause of end-stage renal disease (ESRD) and accounts for 35% of the ESRD population in the United States. It results in considerable morbidity, mortality, and expense. The average cost of managing one diabetic patient with ESRD is approximately $50,000 a year.
openaire   +3 more sources

Sarcopenia in diabetic nephropathy: a cross-sectional study

open access: yesRomanian Journal of Internal Medicine, 2018
Objective. To investigate the relationship between sarcopenia and diabetic nephropathy.
Çeliker Meral   +2 more
doaj   +1 more source

Pathology identifies glomerular treatment targets in diabetic nephropathy

open access: yesKidney Research and Clinical Practice, 2018
The development of the glomerular injury in diabetic nephropathy involves interactions between podocytes, endothelium, and the mesangium. Loss of podocytes is an early and critical step in the development of diabetic nephropathy, and analysis of ...
Charles E. Alpers, Kelly L. Hudkins
doaj   +1 more source

Urinary transferrin as an early biomarker of diabetic nephropathy [PDF]

open access: yesVojnosanitetski Pregled, 2019
Background/Aim. Diabetic nephropathy is one of the leading cause of chronic kidney disease and end-stage renal disease. It occurs in 20%–40% of patients with diabetes mellitus and microalbuminuria is still considered as the first sign of diabetic ...
Terzić Brankica   +9 more
doaj   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals with Type 2 Diabetes

open access: yesArthritis Care &Research, Accepted Article.
Objective Knee osteoarthritis (OA) commonly affects individuals with Type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King   +10 more
wiley   +1 more source

Progression of diabetic nephropathy after successful pancreas transplantation alone: a case report

open access: yesKorean Journal of Transplantation, 2019
Pancreas transplantation is the only method that can nearly cure insulin-dependent diabetes mellitus. However, the effect of pancreas transplantation on patients with diabetic nephropathy has recently been considered controversial.
Yoonhong Kim   +7 more
doaj   +1 more source

Albumin-induced apoptosis of tubular cells is modulated by BASP1 [PDF]

open access: yes, 2015
Albuminuria promotes tubular injury and cell death, and is associated with faster progression of chronic kidney disease (CKD) to end-stage renal disease.
Cannata, Pablo   +9 more
core   +2 more sources

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

A stepwise data interpretation process for renal amyloidosis typing by LMD-MS

open access: yesBMC Nephrology, 2022
Backgrounds Systemic amyloidosis is classified according to the deposited amyloid fibril protein (AFP), which determines its best therapeutic scheme. The most common type of AFP found are immunoglobulin light chains.
Ming Ke   +4 more
doaj   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

open access: yesAdvanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu   +14 more
wiley   +1 more source

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