Results 31 to 40 of about 115,506 (337)

Lipídeos na nutrição de cães e gatos: metabolismo, fontes e uso em dietas práticas e terapêuticas Lipids in dogs and cats nutrition: metabolism, sources and application in practical and therapeutic diets

Revista Brasileira de Zootecnia, 2009
A partir do desenvolvimento de métodos mais precisos para a avaliação de lipídeos, diversos compostos têm sido descobertos e estudados como forma de enriquecer e melhorar dietas para atender às necessidades dos animais.
Luciano Trevizan, Alexandre de Mello Kessler   +1 more
doaj   +1 more source

Diacylglycerol-mediated insulin resistance [PDF]

Nature Medicine, 2010
Understanding the molecular mechanisms of insulin resistance remains a major medical challenge of the twenty-first century. Over the last half-century, many hypotheses have been proposed to explain insulin resistance, and, most recently, inflammation associated with alterations in adipocytokines has become the prevailing hypothesis.
Derek M, Erion, Gerald I, Shulman
openaire   +2 more sources

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]

, 2010
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud, Farese, Robert V, Harris, Charles, Herker, Eva, Hernandez, Céline, Kaehlcke, Katrin, Ott, Melanie, Rosenberg, Arielle R   +7 more
core   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Hepatic insulin sensitivity is improved in high‐fat diet‐fed Park2 knockout mice in association with increased hepatic AMPK activation and reduced steatosis

Physiological Reports, 2019
Park2 is an E3 ubiquitin ligase known for its role in mitochondrial quality control via the mitophagy pathway. Park2 KO mice are protected from diet‐induced obesity and hepatic insulin sensitivity is improved in high‐fat diet (HFD)‐fed Park2 KO mice even
Lia R. Edmunds, Brydie R. Huckestein, Mario Kahn, Dongyan Zhang, Yanxia Chu, Yingze Zhang, Stacy G. Wendell, Gerald I. Shulman, Michael J. Jurczak   +8 more
doaj   +1 more source

Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice

Journal of Lipid Research, 2015
Lipin proteins (lipin 1, 2, and 3) regulate glycerolipid homeostasis by acting as phosphatidic acid phosphohydrolase (PAP) enzymes in the TG synthesis pathway and by regulating DNA-bound transcription factors to control gene transcription.
George G. Schweitzer, Zhouji Chen, Connie Gan, Kyle S. McCommis, Nisreen Soufi, Roman Chrast, Mayurranjan S. Mitra, Kui Yang, Richard W. Gross, Brian N. Finck   +9 more
doaj   +1 more source

Sesame oil inhibits the formation of glycidyl ester during deodorization

International Journal of Food Properties, 2021
Glycidyl ester (GE) has attracted worldwide attention due to its potential harm to human health. The GE in edible oil forms during the deodorization process of the oil refining, where antioxidants are used to inhibit its formation.
Lipeng Han, Jiahui Li, Shujie Wang, Weiwei Cheng, Lukai Ma, Guoqin Liu, Dongxue Han, Li Niu   +7 more
doaj   +1 more source

Immobilized Lipase in the Synthesis of High Purity Medium Chain Diacylglycerols Using a Bubble Column Reactor: Characterization and Application

Frontiers in Bioengineering and Biotechnology, 2020
Novozym® 435, an immobilized lipase from Candida antarctica B. (CALB), was used as a biocatalyst for the synthesis of high purity medium chain diacylglycerol (MCD) in a bubble column reactor.
Jiazi Chen, Wan Jun Lee, Chaoying Qiu, Shaolin Wang, Guanghui Li, Yong Wang   +5 more
doaj   +1 more source

Changes in Plasma Bioactive Lipids and Inflammatory Markers during a Half-Marathon in Trained Athletes

Applied Sciences, 2021
Background: Exercise may affect lipid profile which in turn is related to inflammation, although changes of ceramides, diacylglycerols-DAG and sphingomyelin-SM and their relationship with inflammatory parameters following a half-marathon have never been ...
Melania Gaggini, Cristina Vassalle, Fabrizia Carli, Maristella Maltinti, Laura Sabatino, Emma Buzzigoli, Francesca Mastorci, Francesco Sbrana, Amalia Gastaldelli, Alessandro Pingitore   +9 more
doaj   +1 more source

Cannabinoids in the treatment of epilepsy: current status and future prospects [PDF]

, 2020
Cannabidiol (CBD) is one of the prominent phytocannabinoids found in Cannabis sativa, differentiating from Δ9-tetrahydrocannabinol (THC) for its non-intoxicating profile and its antianxiety/antipsychotic effects.
Albini M., Cifelli P., Di Bonaventura C., Fanella M., Giallonardo A. T., Morano A., Palma E.   +6 more
core   +1 more source