Results 91 to 100 of about 12,487 (210)

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

open access: yesThe FEBS Journal, Volume 293, Issue 5, Page 1386-1399, March 2026.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima   +11 more
wiley   +1 more source

Hyaluronic Acid-Based Nanocapsules as Efficient Delivery Systems of Garlic Oil Active Components with Anticancer Activity

open access: yesNanomaterials, 2021
Diallyl disulfide (DADS) and diallyl trisulfide (DATS) are garlic oil compounds exhibiting beneficial healthy properties including anticancer action. However, these compounds are sparingly water-soluble with a limited stability that may imply damage to ...
Małgorzata Janik-Hazuka   +8 more
doaj   +1 more source

Machine Learning Integration Framework Constructs a Lactylation‐Associated Gene Signature to Improve Prognosis in Bladder Cancer

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Bladder cancer remains a significant challenge in oncology owing to its high recurrence rates and limited treatment options, particularly in cases of resistance to standard therapies. Aims Our study aimed to pinpoint a lactylation‐associated gene signature capable of predicting prognosis and providing important theoretical support ...
Jingsong Wang   +8 more
wiley   +1 more source

H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)-cholesteryl conjugates [PDF]

open access: yes, 2020
Inspired by the properties of the naturally occurring HS donor, diallyl trisulfide (DATS, extracted from garlic), the biological behaviour of trisulfide-bearing PEG-conjugates was explored.
Davis, Thomas P.   +4 more
core   +1 more source

Volatile and non-volatile compounds and antimicrobial activity of Mansoa difficilis (Cham.) Bureau & K. Schum: (Bignoniaceae)

open access: yesQuímica Nova, 2012
Essential oil from the leaves of Mansoa difficilis was analyzed by GC/MS. Oct-1-en-3-ol (49.65%) was the major compound, but diallyl di- and trisulfide were also present (0.85 and 0.37%, respectively), justifying the garlic-like odor of the crushed ...
Giselle Maria Skelding Pinheiro Guilhon   +5 more
doaj   +1 more source

CpG Methylation‐Driven Pleiotropic Spliced Isoforms of PRSS3 Facilitate Gastric Intratumor Heterogeneity and Metastasis

open access: yesCancer Science, Volume 117, Issue 1, Page 33-49, January 2026.
Aberrant spliced isoforms of PRRS3, which are regulated by epigenetic mechanisms, contribute to increased cellular heterogeneity and promote metastasis in gastric cancer (GC). This study underscores the significant involvement of methylation‐driven alternative splicing in tumor heterogeneity and suggests that these spliced isoforms may serve as more ...
Mengdi Pang   +15 more
wiley   +1 more source

Diallyl trisulfide reduced the reproductive capacity of male Sitotroga cerealella via the regulation of juvenile and ecdysone hormones.

open access: yesEcotoxicology and Environmental Safety, 2022
Environmental pollution and resistance in animals are major concerns for the application of synthetic pesticides. Diallyl trisulfide (DAT), an active compound in garlic essential oil, is a novel tool for active and safe control of agricultural insect ...
Sakhawat Shah   +6 more
semanticscholar   +1 more source

In silico evaluation of garlic-derived organosulfur compounds as multi-target inhibitors of breast cancer biomarkers.

open access: yesPLoS ONE
Breast cancer is the leading cause of cancer mortality among women globally, and drug resistance complicates treatment. Garlic-derived organosulfur compounds exhibit anticancer potential, but their multi-target activity against key breast cancer ...
Courage Siame   +3 more
doaj   +1 more source

Potentiality of Organosulfur Compounds Against SARS-CoV-2-Coinfected Bacteria and : A Cross-Platform Analysis from Computational Chemistry

open access: yesNatural Product Communications, 2023
Objective SARS-CoV-2 coinfection with Streptococcus pyogenes and S pneumoniae increases disease severity, thus deserving more in-depth understanding.
Nguyen Minh Thai   +11 more
doaj   +1 more source

Essential Oils and Plant Extracts for Postharvest Control of Monilinia fructicola in Peaches: Direct Antifungal Activity and Defence Induction

open access: yesJournal of Phytopathology, Volume 174, Issue 1, January/February 2026.
ABSTRACT This study evaluated the antifungal potential of essential oils and plant extracts for the control of Monilinia fructicola, the causal agent of brown rot in peaches, under in vitro and postharvest conditions. Essential oils and cold aqueous, hot aqueous, and hydroalcoholic extracts of Allium sativum, Syzygium aromaticum, Origanum vulgare ...
Ediane Roncaglio Baseggio   +4 more
wiley   +1 more source

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