Results 131 to 140 of about 12,487 (210)

Hydrogen Sulfide Signaling Axis as a Target for Prostate Cancer Therapeutics

Prostate Cancer, 2016
Hydrogen sulfide (H2S) was originally considered toxic at elevated levels; however just in the past decade H2S has been proposed to be an important gasotransmitter with various physiological and pathophysiological roles in the body.
Mingzhe Liu, Lingyun Wu, Sabine Montaut, Guangdong Yang   +3 more
doaj   +1 more source

Diallyl Trisulfide Modulates Notch Pathway Components in Breast Cancer Cells

, 2016
Breast cancer affects one in eight women throughout the course of their lifetimes creating an immediate demand for novel prevention strategies against this disease.
Kiesel, Violet Abigail, Kiesel, Violet
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Diallyl trisulfide exerts anti-inflammatory effects in lipopolysaccharide-stimulated RAW 264.7 macrophages by suppressing the Toll-like receptor 4/nuclear factor-kappa B pathway

, 2015
Diallyl trisulfide (DATS; di-2-propen-1-yl trisulfide) is an organic polysulfide compound found in garlic and other allium vegetables. Although certain studies have demonstrated that DATS possesses strong anti-inflammatory activity, the underlying ...
Hyun, Jin-Won, Kim, Wun-Jae, Kim, Gi-Young, Han, Min Ho, Hwang, Hye Jin, Choi, Yung Hyun, Moon, Sung-Kwon, Lee, Hye Hyeon   +7 more
core   +1 more source

Diallyl Trisulfide Protects Rats from Carbon Tetrachloride-Induced Liver Injury

Alk(en)yl sulfides have been found to be responsible for the anticancer, antithrombotic, and antioxidant effects of garlic. We sought to identify the most potent structure of sulfides that exhibits a hepatoprotective effect against carbon tetrachloride ...
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Molecular mechanisms and targets of cancer chemoprevention by garlic-derived bioactive compound diallyl trisulfide

, 2011
805-816Health benefits of garlic and other Allium vegetables (e.g., onions), such as lipid lowering and anticancer effects, are credited to metabolic byproducts, including diallyl trisulfide (DATS).
Antony, Marie Lue, Singh, Shivendra V
core  

Quantitative GC-FID Analysis of DADS and DATS in Commercial Garlic Products: Effects of Product Formulation and Processing

Applied Sciences
Diallyl disulfide (DADS) and diallyl trisulfide (DATS) are major allicin-derived organosulfur compounds associated with biological activity and sensitivity to processing conditions. This study aimed to quantify DADS and DATS in commercial garlic products
Judit Császár, Lívia Vencel, István Rudolf Nagy, Gábor Pál Stromájer, Tímea Stromájer-Rácz   +4 more
doaj   +1 more source

The Effects and Role of the Natural Compounds Curcumin and Diallyl Trisulfide on Glioblastoma Cell Lines

, 2016
Glioblastoma, one of the most lethal forms of astrocytoma, has a median survival rate of fifteen months post diagnosis. Due to its multiple pathways that allow this cancer to quickly grow, divide, and invade the brain, glioblastoma has a high recurrence ...
Estrada, Megan, \u2717, Mejias, Wincy Phine, \u2717   +1 more
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Diallyl trisulfide plays an antifibrotic role by inhibiting the expression of Bcl-2 in hepatic stellate cells. [PDF]

J Biochem Mol Toxicol, 2022
Pang H, Wang C, Ye J, Wang L, Zhou X, Ge X, Zhang J, Liu Q.   +7 more
europepmc   +1 more source

Apoptosis of rat hepatic stellate cells induced by diallyl trisulfide and proteomics profiling in vitro

, 2016
Diallyl trisulfide (DATS), a major garlic derivative, inhibits cell proliferation and triggers apoptosis in a variety of cancer cell lines. However, the effects of DATS on hepatic stellate cells (HSCs) remain unknown.
Zhang, Ya-jie, Liu, Qinghua, Xu, Lipeng, Ye, Jing, Zhou, Xiaoming, Liu, Jinling, Qiu, Pengxin, Wang, Lulu   +7 more
core   +1 more source

Apoptosis induction of U937 human leukemia cells by diallyl trisulfide induces through generation of reactive oxygen species

, 2012
Background Diallyl trisulfide (DATS) is one of the major constituents in garlic oil and has demonstrated various pharmacological activities, including antimicrobial, antihyperlipidemic, antithrombotic, and anticancer effects.
Choi Yung, Park Hyun
core   +1 more source