The Garlic Compound, Diallyl Trisulfide, Attenuates Benzo[a]Pyrene-Induced Precancerous Effect through Its Antioxidant Effect, AhR Inhibition, and Increased DNA Repair in Human Breast Epithelial Cells. [PDF]
Ferguson DT +8 more
europepmc +1 more source
The Mitochondrial Ca2+ Overload via Voltage-Gated Ca2+ Entry Contributes to an Anti-Melanoma Effect of Diallyl Trisulfide. [PDF]
Nakagawa C +4 more
europepmc +1 more source
The Anticancer Effects of the Garlic Organosulfide Diallyl Trisulfide through the Attenuation of B[a]P-Induced Oxidative Stress, AhR Expression, and DNA Damage in Human Premalignant Breast Epithelial (MCF-10AT1) Cells. [PDF]
Ferguson DT +10 more
europepmc +1 more source
Effect of Diallyl Trisulfide on the Reproductive Behavior of the Grain Moth, Sitotroga cerealella (Lepidoptera: Gelechiidae). [PDF]
Chang MM +5 more
europepmc +1 more source
Diallyl trisulfide attenuates hyperglycemia-induced endothelial apoptosis by inhibition of Drp1-mediated mitochondrial fission. [PDF]
Hao Y +5 more
europepmc +1 more source
Garlic-derived allyl sulfides attenuate house dust mite-induced allergic airway inflammation associated with reduced PI3K/NF-κB signaling. [PDF]
Liu HC +6 more
europepmc +1 more source
Dietary Bioactive Diallyl Trisulfide in Cancer Prevention and Treatment [PDF]
Bioactive dietary agents have been shown to regulate multiple cancer hallmark pathways. Epidemiologic studies have linked consumption of Allium vegetables, such as garlic and onions, to decreased incidence of cancer. Diallyl trisulfide (DATS), a bioactive compound derived from Allium vegetables, has been investigated as an anti-cancer and ...
Silvia D. Stan
exaly +4 more sources
Identification of Molecular Target of Diallyl Trisulfide in Leukemic Cells [PDF]
Abstract To identify the molecular target of diallyl trisulfide (DATS) in human leukemic cell line U937, we examined modification of thiol group(s) of cellular proteins by the redox 2D PAGE. A unique protein spot appeared by DATS treatment was identified to be heat shock protein 27 (HSP27).
Takashi Hosono +2 more
exaly +3 more sources
Effects of Garlic Oil and Diallyl Trisulfide on Glycemic Control in Diabetic Rats
We investigated the effects of garlic oil and diallyl trisulfide on glycemic control in rats with streptozotocin-induced diabetes. Diabetic rats received by gavage garlic oil (100 mg/kg body weight), diallyl trisulfide (40 mg/kg body weight), or corn oil every other day for 3 weeks. Control rats received corn oil only.
Lee-Yan Sheen +2 more
exaly +4 more sources
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Neuroprotective Potential of Phase II Enzyme Inducer Diallyl Trisulfide
Neurological Research, 2009Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease, selectively involving the upper and lower motor neurons. Glutamate excitotoxicity and oxidative stress are important mechanisms for the pathogenesis of ALS. Nuclear-factor erythroid 2-related factor 2 (Nrf2) is a master transcriptional regulator of many cytoprotective genes.
Chun-Yan Li, Yan-Su Guo
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