Results 171 to 180 of about 3,935 (193)
Effect of Diallyl Trisulfide on Ischemic Tissue Injury and Revascularization in a Diabetic Mouse Model. [PDF]
J Cardiovasc Pharmacol, 2018 Yang HB, Liu HM, Yan JC, Lu ZY.
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Increased Sulfiredoxin Expression in Gastric Cancer Cells May Be a Molecular Target of the Anticancer Component Diallyl Trisulfide. [PDF]
Biomed Res Int, 2019 Wang J, Si L, Wang G, Bai Z, Li W.
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Degradation Urushiol Coating Composition Crosslinked by Diallyl Trisulfide
Journal of Polymers and the Environment, 2020Urushiol (UR) was a kind of natural paint with a long history and excellent performance. Its high price restricts its development. For the sake of the sustainable development of UR, we prepared a new urushiol based coating composition which is of degradation.
Hanyu Xue +4 more
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Neuroprotective potential of phase II enzyme inducer diallyl trisulfide
Neurological Research, 2009Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease, selectively involving the upper and lower motor neurons. Glutamate excitotoxicity and oxidative stress are important mechanisms for the pathogenesis of ALS. Nuclear-factor erythroid 2-related factor 2 (Nrf2) is a master transcriptional regulator of many cytoprotective genes.
Meng-Meng, Sun +5 more
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Diallyl trisulfide ameliorates arsenic induced dyslipidemia in rats
Food Science and Biotechnology, 2015The efficacy of diallyl trisulfide (DATS) against arsenic (As) induced dyslipidemia in the plasma and livers of rats was studied.
Selvaraj Miltonprabu +1 more
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Diallyl Trisulfide Inhibits Platelet Aggregation through the Modification of Sulfhydryl Groups
Journal of Agricultural and Food Chemistry, 2020Diallyl trisulfide (DATS) is a secondary metabolite of allicin, a volatile organosulfur flavoring compound generated by the crushing of garlic. These compounds have various medicinal effects such as antiplatelet activity. In this study, we demonstrated for the first time the cellular mechanism involved in the inhibition of platelet aggregation by DATS ...
Takashi Hosono +4 more
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Effect of diallyl trisulfide on the pharmacokinetics of dipyridamole in rats
Archives of Pharmacal Research, 2011This study was aimed to evaluate the effect of diallyl trisulfide (DATS), a major component derived from garlic used to inhibit platelet thromboxane formation, on the pharmacokinetics of dipyridamole. Pharmacokinetic parameters of dipyridamole were determined in rats following intragastric (80 mg/kg suspension or 40 mg/kg solution) or intravenous (3 mg/
Yue, Wang +5 more
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Free Radical Biology and Medicine, 2022
Radiotherapy is a standard-of-care treatment approach for glioblastoma (GBM) patients, but therapeutic resistance to radiotherapy remains a major challenge. Here we demonstrate that diallyl trisulfide (DATS) directly conjugates with cysteine (C) 32 and C35 (C32/35) residues of thioredoxin 1 (Trx1) through Michael addition reactions.
Yangyang Tian +10 more
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Radiotherapy is a standard-of-care treatment approach for glioblastoma (GBM) patients, but therapeutic resistance to radiotherapy remains a major challenge. Here we demonstrate that diallyl trisulfide (DATS) directly conjugates with cysteine (C) 32 and C35 (C32/35) residues of thioredoxin 1 (Trx1) through Michael addition reactions.
Yangyang Tian +10 more
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Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog
Nutrition and Cancer, 2022Cancer stem-like cells (CSCs), which play an important role in tumor initiation and progression, have been identified in many cancers. Diallyl trisulfide (DATS) is an organosulfur compound extracted from garlic with anticancer activities. Nanog is a transcription factor responsible for maintaining the stemness of CSCs, but its role in the DATS-induced ...
Taotao Zhang +4 more
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In vitro anti-synovial sarcoma effect of diallyl trisulfide and mRNA profiling
Gene, 2022Synovial sarcoma (SS) is a malignant soft tissue sarcoma and its natural history is a long, indolent clinical course followed by high rate of local recurrence and distant metastasis. Current therapies are still limited in increasing satisfactory of 5-year survival, especially for patients with recurrence and metastasis.
Sheng-Li, Xia +7 more
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