Results 161 to 170 of about 35,698 (262)

Diastereomeric Branched-Ester dBET1 Analogs Exhibit Conformation-Dependent Differences in Passive Membrane Permeability. [PDF]

J Med Chem
Abdelwahid MAS, Hayakawa E, Hirai K, Ishii M, Kanamitsu K, Yasuda S, Ohtake F, Sato S, Tomoshige S, Ishikawa M.   +9 more
europepmc   +1 more source

Catalytic Hydrogenation of Lignin‐Derived Aromatics With Rhodium Oxide in Water

European Journal of Organic Chemistry, Volume 29, Issue 14, 15 April 2026.
The easily available, easy‐to‐handle rhodium(III) oxide, Rh2O3, is shown to be a competent catalyst for arene hydrogenation, including chemoselective reduction of α,β‐unsaturated aryl ketones. Catalytic arene hydrogenation offers a direct pathway to saturated carbocycles. It can also be exploited to upgrade lignin‐derived aromatics.
Zhenyu Chen, Leiming Qi, Sydney Williams, Ilkan Calisir, Shamsal Haq, Rasmita Raval, Changzhi Li, Tao Zhang, Jianliang Xiao   +8 more
wiley   +1 more source

Synthesis of Polyhydroxylated Pyrrolidinyl Analogs of Sugar Nucleotides. Experimental and Computational Studies on Their Interactions With GalNAC‐T's

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A multidisciplinary approach based on organic synthesis supported by quantum mechanical calculations, efficient phosphorylation methods, affinity studies using conventional techniques and saturation transfer difference nuclear magnetic resonance, together with molecular dynamics simulations, has enabled the preparation of nucleotide analogs with ...
Pedro Merino, Veronica Juste, Alejandro Montesa, Sandra Pereira, Sara Orta, Manuel Pedrón, Ana I. Jiménez, Sonsoles Martín‐Santamaría, Ramón Hurtado‐Guerrero, Ignacio Delso, Tomás Tejero   +10 more
wiley   +1 more source

Competitive cyclization of ethyl trifluoroacetoacetate and methyl ketones with 1,3-diamino-2-propanol into hydrogenated oxazolo- and pyrimido-condensed pyridones. [PDF]

Beilstein J Org Chem
Kushch SO, Goryaeva MV, Burgart YV, Ezhikova MA, Kodess MI, Slepukhin PA, Volobueva AS, Zarubaev VV, Saloutin VI.   +8 more
europepmc   +1 more source

A Streamlined Synthesis of Adenosine Vinylsulfonamide Probes for Aminoacyl‐AMP Mimicry in NRPS

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A concise three‐step synthesis enables access to amino acid‐derived adenosine vinylsulfonamide (AVS) probes under mild conditions. Ba(OH)2‐mediated coupling suppresses epimerization, affording stereochemically defined probes that covalently capture nonribosomal peptide synthetase (NRPS) thioesterification states. LC–MS/MS confirms functional engagement
Naoto Haraguchi, Arisa Suto, Takashi Matsui, Yoshio Kodera, Yoshikazu Tanaka, Ryo Tanifuji, Hiroki Oguri   +6 more
wiley   +1 more source

Induced Photoelectron Circular Dichroism as a Probe for Distinguishing Diastereotopic Lone Electron Pairs

Angewandte Chemie, Volume 138, Issue 15, 6 April 2026.
Gas‐phase complexation of chiral methyloxirane by achiral phenol results in induced chiroptical response of phenol. Two pseudo enantiomer complexes are observed, corresponding to hydrogen bonding from phenol to either of the lone electron pair of the methyloxirane oxygen, denoted as Pro R and Pro S, with opposite chiral deformation of phenol and ...
Etienne Rouquet, Valéria Lepère, Gustavo A. Garcia, Laurent Nahon, Rodolphe Vuilleumier, Anne Zehnacker   +5 more
wiley   +2 more sources

Stereoselective Total Synthesis of (+)-Giganin and Its C10 Epimer by Using Late-Stage LithiationBorylation Methodology [PDF]

, 2013
Alali, Bandur, Beckmann, Besong, Blakemore, Crimmins, Curran, Davoli, De Luca, Dearden, Debré, Dixon, Donohoe, Donohoe, Duret, Duval, Elford, Esposti, Fang, Furuhata, Gao, Gralla, Griggs, Hattori, Hiscox, Hoppe, Hu, Hu, Huh, Kolb, Larouche-Gauthier, Liu, Marshall, Matteson, Matteson, Matteson, Matteson, Matteson, McLaughlin, Miyoshi, Oasa, Oberlies, Okun, Persich, Sohn, Strand, Strand, Strand, Stymiest, Takahashi, Takahashi, Takahashi, White, Yamamoto, Ye, Yu   +55 more
core   +3 more sources

Chirally locked and dynamic bis-perylene diimide macrocycles with multiple sources of chirality. [PDF]

Commun Chem
Hartmann D, Penty SE, Pal R, Barendt TA.
europepmc   +1 more source

Separation of PS diastereomers in GalNAc-conjugated siRNA-a comparative study of chromatographic and ion mobility mass spectrometry approaches. [PDF]

Anal Bioanal Chem
Bill MK, Graglia M, Riley JA, Zugaj M, Demtschenko N, Fox J, Bethge L, Smink JJ, Manz C.   +8 more
europepmc   +1 more source

Liquid chromatographic determination of enantiomeric purity of [¹¹C]methyl-L-methionine and O-(2-[¹⁸F]fluoroethyl)-L-tyrosine by pre-column derivatization with o-phthaldialdehyde and N-isobutyryl-L-cysteine. [PDF]

EJNMMI Radiopharm Chem
Forgács V, Balla V, Csonka V, Szikra D, Szücs D, Németh E, Képes Z, Trencsényi G, Jószai I.   +8 more
europepmc   +1 more source