Results 141 to 150 of about 35,698 (262)
The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1
The FEBS Journal, EarlyView.ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu +2 more
wiley +1 more source
AIChE Journal, Volume 72, Issue 5, May 2026.Abstract Three instruments–Raman spectroscopy, attenuated total reflectance–Fourier transform infrared spectroscopy, and focused beam reflectance measurement–were used to detect sensor faults, mixing faults, and unanticipated chemistry in a system of multicomponent slurries.
Steven H. Crouse +2 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.A NiH‐catalyzed α‐alkenylation via Markovnikov hydronickellation of alkynes enables convenient access to α‐chrial β‐methylene carbonyl frameworks that are prevalent in biorelevant molecules. High regio‐ and enantioselectivities have been achieved with excellent functional group tolerance and applicability toward complex structures. The β‐methylene unit
Hyeontaek Nam +3 more
wiley +2 more sources
Spectroscopy and Conformer‐Selective Photoelectron Circular Dichroism of Chiral Molecules
Chemistry – An Asian Journal, Volume 21, Issue 9, 14 May 2026.Photoelectron circular dichroism (PECD) is a forward–backward asymmetry in the angular distribution of the electrons emitted by a chiral molecule ionized by a circularly polarized light (CPL). Its sensitivity to conformation is studied by one‐photon or resonance‐enhanced two‐photon ionization, the latter being conformer‐selective.
Laurent Nahon, Anne Zehnacker
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.Manganese porphyrin catalyst enables green PhI(OAc)2 oxidation of lupeol in ethyl acetate, achieving 94% conversion and the formation of eight products, including selective C20 olefin transformations and one‐pot conversion of the isopropenyl group to carboxylic acids, all without the need of C3‐OH protection step.
Leila Renan Oliveira +5 more
wiley +1 more source
Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications
Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff +2 more
wiley +1 more source
Dual Cluster‐Surface Click Chemistries on Silver Nanoclusters
Small Science, Volume 6, Issue 5, May 2026.In this report, two new structures of clickable anion templated silver nanoclusters (NCs) equipped with azide functional groups capable of cluster surface click reactions are described. It is demonstrated for the first time the Staudinger–Bertozzi ligation and dual click reactions Staudinger–Bertozzi ligation‐strain‐promoted azide–alkyne cycloadditions
Carolina Vega Verduga +5 more
wiley +1 more source
Planar Chirality Controls Diastereotopicity in [2.2]Paracyclophanyl Cyclopropenes
Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.In this work, we report the synthesis of [2.2]paracyclophane‐substituted cyclopropenes via rhodium‐catalyzed cyclopropenation using a pCp‐derived carbene precursor. The planar chiral framework induces diastereotopic differentiation of otherwise equivalent alkyl substituents, which is reflected in their 1H NMR spectra.
Tilman Köhler +3 more
wiley +1 more source
Stereocontrolled Synthesis of Polysubstituted Housanes via <i>gem</i>-Bismetalated Cyclopropanes. [PDF]
J Am Chem SocOrbach N, Suresh R, Marek I.
europepmc +1 more source