Results 141 to 150 of about 14,574 (240)

Photochemical Ring Opening of Cyclopropyl Silyl Ethers Enables β–β Coupling, Radical‐Polar Crossover and Annulation

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
A photochemical platform enables β–β coupling of cyclopropyl silyl ethers with electron‐deficient alkenes. The resulting adducts serve as entry points into annulative and radical–polar crossover pathways, providing rapid access to fused, bridged, and spirocyclic architectures, including late‐stage scaffold diversification to diterpene‐like carbocyclic ...
Jacop Rydén, Eilidh Young, Wilma Olsson, Eskil Flodén, Mattias Tan, Sebastian Clementson   +5 more
wiley   +2 more sources

A Diastereomeric Hydroxycurvularin Mixture Inhibits Melanogenesis and Inflammation <i>via</i> Modulation of Tyrosinase Activity and Cytokine Expression. [PDF]

J Microbiol Biotechnol
Seo JH, Koo HS, Mai VH, Kim SB, Seong GH, Nguyen TTT, Seon JE, Choi HR, Lee HB, Oh WK, Kang HS.   +10 more
europepmc   +1 more source

A Bio‐Based Chiroptical Overcrowded Alkene From Flavanone: Photoreactivity and Theoretical Investigation

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
A sustainable route to photoresponsive molecular systems is achieved using the bio‐based flavanone (‐)‐isolonchocarpin from Tephrosia vogelii. Through McMurry homocoupling and light‐driven 6‐π‐electrocyclization, an overcrowded alkene and a fluorescent O‐heterocyclic phenanthrene are synthesized.
Deryl H. Limawan, Adrien Combe, Anthony Bongso, Bayu Dwiputra, Atthar L. Ivansyah, Roza R. Weber, Charlotte N. Stindt, Robby Roswanda, Ben L. Feringa   +8 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Formal Total Synthesis of (±)-Isoalantolactone. [PDF]

Org Lett
Olsson W, Wennerberg J, Clementson S.
europepmc   +1 more source

Truncation of Samroiyotmycin: Tailored seco‐Acids as Novel Antimalaria Compounds

European Journal of Organic Chemistry, Volume 29, Issue 34, 11 September 2026.
Six truncated samroiyotmycin‐derived antimalarials were synthesized by replacing the tosyloxazole unit with electron‐deficient aryl groups. The most active seco‐acid with EWG = 2 × CF3 outperformed the natural product SamA. Its enhanced activity supports a donor–acceptor interaction involving the electron‐poor aryl unit, consistent with inhibition of ...
Anton Czuczkowski, Anja Schäfer, Juliana A. Hüther, Bianca Wank, Robert Toews, Fotios Fotakis, Andreas Köhn, Markus Rehm, Matthias Rottmann, Anna Zens, Sabine Laschat   +10 more
wiley   +1 more source

Conversion of Alkenes Into Simple or Functionalized Aldehydes by Reaction With an Ambiphilic Masked Formyl Radical. [PDF]

Angew Chem Int Ed Engl
Lai SQ, Zhao PF, Wang ZS, Wang HC, Wang XJ, Zhu LY, Han B.   +6 more
europepmc   +1 more source

Catalytically Promiscuous PLP-Dependent Aminotransferases Are Biocatalysts for C-C Bond Formation. [PDF]

ACS Cent Sci
Kim AT, Howard JR, Cuba Cáceres AG, Chong KI, Aye WA, Sigman MS, Narayan ARH.   +6 more
europepmc   +1 more source

Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues. [PDF]

ACS Med Chem Lett
Elhalawaty EA, Alseedy HA, Woodland JG, Wicht KJ, Swart T, Rangel GW, Hoppe HC, Chibale K, Llinás M, Abadi AH, Ahmed NS.   +10 more
europepmc   +1 more source

Mechanistic Insights into Regioselective Arene Insertion Using Bis(phosphine) Cobalt(I) Hydrides to Form 1,3-Cyclohexadienes. [PDF]

Organometallics
Lebowitz MJ, Mendelsohn LN, Zhong H, Pecoraro MV, Shevlin M, Chirik PJ.   +5 more
europepmc   +1 more source