Results 31 to 40 of about 14,574 (240)

Diastereomers of Spheroidal Form and Commercially Available Taxifolin Samples

Scientia Pharmaceutica
Taxifolin is a natural polyphenol belonging to the class of flavonoids. The structure of this compound is characterized by the presence of two chiral centers. The spheroidal form of taxifolin (TAXs) has emerged as a promising modification due to enhanced
Roman P. Terekhov, Evgeny S. Melnikov, Ilya D. Nikitin, Margarita A. Tokareva, Tatyana A. Rodina, Anastasiya D. Savina, Denis I. Pankov, Anastasiya K. Zhevlakova, Vladimir L. Beloborodov, Irina A. Selivanova   +9 more
doaj   +1 more source

Bromidocarbonyl{(1S,2S)-N-[2-(dicyclohexylphosphanyl)ethylidenyl]-N′-[2-(diphenylphosphanyl)ethyl]-1,2-diphenylethane-1,2-diamine}iron(II) tetraphenylborate

IUCrData, 2017
In the title compound, trans-(S,S)-[FeBr(CO)(PPh2CH2CH2NHCHPhCHPhNCHCH2PCy2)]BPh4, the FeII ion is in a distorted octahedral complex geometry with a cis-β ligand geometry in which two diastereomers co-crystallized in the asymmetric unit.
Samantha A. M. Smith, Alan J. Lough, Robert H. Morris   +2 more
doaj   +1 more source

Synthesis and stereochemistry of 6-membered ring phosphonates [PDF]

QScience Connect, 2012
Background: Organophosphorus compounds have important industrial and biomedical applications as pharmaceutical and agrochemical agents, as well as transition state analogs for the production of monoclonal antibodies.
Michael D. Pungente, Larry Weiler
doaj   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

Angewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang, Hsuan‐Hung Liao   +1 more
wiley   +2 more sources

Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams

ChemistryOpen, 2023
Trans‐β‐lactam isomers have garnered much attention as anti‐cancer microtubule targeting agents. Currently available synthetic methods are available for the preparation of enantiopure β‐lactams and favour isomeric cis/trans β‐lactam mixtures.
Eavan C. McLoughlin, Dr. John E. O'Brien, Dr. Cristina Trujillo, Prof. Mary J. Meegan, Prof. Niamh M. O'Boyle   +4 more
doaj   +1 more source

Highly Enantio‐ and Diastereoselective Synthesis of Tetrahydrofuran Frameworks via Chiral Lewis Acid‐Catalyzed Formal [3+2] Cycloaddition of Allylsilanes

Angewandte Chemie, EarlyView.
The first catalytic asymmetric formal [3+2] cycloaddition of allylsilanes delivers cis‐2,5‐disubstituted tetrahydrofuran‐3‐ones that serve as versatile intermediates for the synthesis of diverse bioactive scaffolds. ABSTRACT A formal [3+2] cycloaddition via cyclization/1,2‐hydride shift initiated by nucleophilic attack of allylsilanes has been ...
Hosung Lee, Dong Kyu Kim, Pingshan Xin, Jin Won Lee, Terim Seo, Do Hyun Ryu   +5 more
wiley   +2 more sources

Pyrethroid Stereoisomerism: Diastereomeric and Enantiomeric Selectivity in Environmental Matrices – A Review

Orbital: The Electronic Journal of Chemistry, 2018
Pyrethroids are chiral insecticides characterized by stereoisomerism, which occurs due to the presence of one to three asymmetric (chiral) carbons, generating one or two pairs of cis/trans diastereomers, and two or four pairs of enantiomers ...
Cláudio Ernesto Taveira Parente, Claudio Eduardo Azevedo-Silva, Rodrigo Ornellas Meire, Olaf Malm   +3 more
doaj   +3 more sources

Excited States Symmetry Breaking and In-Plane Polarization Cause Chiral Reversal in Diastereomers

Molecules, 2021
In this work, we investigate the electronic transitions and chirality of three isomers of huge conjugated systems: asymmetric diastereomers (MMMM) and two symmetrical diastereomers (PMPM and PPMM).
Chenglong Wang, Jingang Wang, Chunyang Wang   +2 more
doaj   +1 more source

Diastereomers of 5-S-cysteinyldopa

Acta Dermato-Venereologica, 1983
Diastereomers of 5-S-cysteinyldopa formed from D-dopa and L-cysteine or from L-dopa and D-cysteine can be separated from 5-S-cysteinyldopa formed from L-dopa and L-cysteine by liquid chromatography. The diastereomers have a great potential as internal standards in the analysis of 5-S-cysteinyldopa.
G, Agrup, L E, Edholm, H, Rorsman, E, Rosengren   +3 more
openaire   +2 more sources

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

Angewandte Chemie, EarlyView.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee‐Ann J. Keane, Patrick McArdle, Nicholas D. J. Yates, Christopher D. Spicer, Alison Parkin, Martin A. Fascione, Eddie L. Myers   +9 more
wiley   +2 more sources