Results 41 to 50 of about 20,067 (277)

Synthesis and characterization of the diastereomers of HHC and H4CBD

Natural Product Communications, 2023
Abstract The characterization of any compound is important in the field of chemistry. As the field of cannabinoid chemistry grows so does the need for the characterization of new cannabinoids or rare cannabinoids that gain popularity within the consumer and research fields.
Arianna Collins, Giovanni Ramirez, Tesfay Tesfatsion, Kyle P Ray, Scott Caudill, Westley Cruces   +5 more
openaire   +1 more source

A Novel Class of “Super‐Strained” Spiro Heterocycles: Gateway to 1‐Azaspiro[3.3]heptane Derivatives, and Biological Validation

Angewandte Chemie, EarlyView.
A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho, Annarita Vicenti, Marco Colella, Francesco Pasca, Giuseppe Romanazzi, Mauro Niso, Carmen Abate, Ernesto Mesto, Emanuela Schingaro, Renzo Luisi   +9 more
wiley   +2 more sources

Preparation and Use of a General Solid-Phase Intermediate to Biomimetic Scaffolds and Peptide Condensations

Molecules, 2018
The Distributed Drug Discovery (D3) program develops simple, powerful, and reproducible procedures to enable the distributed synthesis of large numbers of potential drugs for neglected diseases.
J. Geno Samaritoni, Jacek G. Martynow, Martin J. O’Donnell, William L. Scott   +3 more
doaj   +1 more source

Protonation‐Gated Orthogonal Control of Highly Efficient Molecular Motors With Broad Visible‐Light Responsiveness

Angewandte Chemie, EarlyView.
Reversible protonation gates coumarin‐based overcrowded‐alkene molecular motors by dynamically reshaping their conjugation topology. This strategy enables efficient, near‐quantitative unidirectional photoisomerization from blue–green to red‐shifted visible light up to 600 nm, while preserving motor function and allowing orthogonal light, heat, and acid/
Jinghao Wang, Alexander Ryabchun, Ben L. Feringa   +2 more
wiley   +2 more sources

Systematic synthetic study of four diastereomerically distinct limonene-1,2-diols and their corresponding cyclic carbonates

Beilstein Journal of Organic Chemistry, 2019
In order to produce versatile and potentially functional terpene-based compounds, a (R)-limonene-derived diol and its corresponding five-membered cyclic carbonate were prepared.
Hiroshi Morikawa, Jun-ichi Yamaguchi, Shun-ichi Sugimura, Masato Minamoto, Yuuta Gorou, Hisatoyo Morinaga, Suguru Motokucho   +6 more
doaj   +1 more source

Intramolecular Hydrogen Bonding in α-Epoxy Alcohols: A Conformational Analysis of 1,2-Dialkyl-2,3-epoxycyclopentanol Diastereomers [PDF]

, 2018
Geometry optimizations for 11 1,2-disubstituted-2,3-epoxycyclopentanol diastereomers were studied using the M06-2X/cc-pVTZ method and basis set to probe mechanistic details in the α-epoxy alcohol semipinacol rearrangement reaction. Electronic energies of
Justin W. Weeks, Gregory S. Tschumper, Yasmeen A. Abdo, Joshua W. Graham, Mikayla E. Tabor, Layfield, William, Tabor, Mikayla E., Carr, Jeremy M., William Layfield, Sarah E. Causey, Weeks, Justin W., Causey, Sarah E., William M. Tremlett, Abdo, Yasmeen A., Tremlett, William M., Jeremy M. Carr, Graham, Joshua W., Tschumper, Gregory S.   +17 more
core   +1 more source

Bromidocarbonyl{(1S,2S)-N-[2-(dicyclohexylphosphanyl)ethylidenyl]-N′-[2-(diphenylphosphanyl)ethyl]-1,2-diphenylethane-1,2-diamine}iron(II) tetraphenylborate

IUCrData, 2017
In the title compound, trans-(S,S)-[FeBr(CO)(PPh2CH2CH2NHCHPhCHPhNCHCH2PCy2)]BPh4, the FeII ion is in a distorted octahedral complex geometry with a cis-β ligand geometry in which two diastereomers co-crystallized in the asymmetric unit.
Samantha A. M. Smith, Alan J. Lough, Robert H. Morris   +2 more
doaj   +1 more source

Synthesis and stereochemistry of 6-membered ring phosphonates [PDF]

QScience Connect, 2012
Background: Organophosphorus compounds have important industrial and biomedical applications as pharmaceutical and agrochemical agents, as well as transition state analogs for the production of monoclonal antibodies.
Michael D. Pungente, Larry Weiler
doaj   +1 more source

Strain‐Release Pentafluorosulfanylation of Carbonyl‐Containing Disubstituted Bicyclobutanes: A Fortuitous Path to SF5‐Containing Oxa[2.1.1]bicyclohexanes

Angewandte Chemie, EarlyView.
A regio‐ and diastereoselective method for strain‐release pentafluorosulfanylation of carbonyl‐containing 1,3‐disubstituted [1.1.0]bicyclobutanes (BCBs) was developed that led to several fortuitous discoveries. For instance, the resultant SF5‐cyclobutanes (SF5‐CBs) exhibit close SF5⋯C═X contacts (X = C, N, O) and provide synthetic access to a new class
Alexander M. Stephens, Jake Anthony Olvera, Yannick Kraemer, Tyson Vu, Wang‐Yeuk Kong, Sudiksha Chaturvedi, Jeffrey M. Wang, Lauren M. Holder, Dean J. Tantillo, Cody Ross Pitts   +9 more
wiley   +2 more sources

Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams

ChemistryOpen, 2023
Trans‐β‐lactam isomers have garnered much attention as anti‐cancer microtubule targeting agents. Currently available synthetic methods are available for the preparation of enantiopure β‐lactams and favour isomeric cis/trans β‐lactam mixtures.
Eavan C. McLoughlin, Dr. John E. O'Brien, Dr. Cristina Trujillo, Prof. Mary J. Meegan, Prof. Niamh M. O'Boyle   +4 more
doaj   +1 more source