Results 11 to 20 of about 35,698 (262)

Rh-Catalyzed Chemodivergent Parallel Kinetic Resolution and Desymmetrization of Enynes and Dienynes with Acrylamides. [PDF]

Angew Chem Int Ed Engl
Rh‐catalyzed chemodivergent parallel kinetic resolution of racemic 1,6‐enynes with α‐fluoroacrylamides or mixtures of different acrylamides proceeded via [2+2+2] cycloaddition and C–H alkylation to afford structurally and stereochemically distinct products with high selectivity under mild conditions.
Hamada S, Jiang J, Sato Y, Yamazaki T, Maeda S, Tanaka K.   +5 more
europepmc   +3 more sources

The diastereoselective Meth-Cohn epoxidation of camphor-derived vinyl sulfones [PDF]

, 2012
Some camphor-derived vinyl sulfones bearing oxygen functionality at the allylic position have been synthesized and their nucleophilic epoxidation reactions under Meth-Cohn conditions have been explored.
Adam, Adamczyk, Adams, Aggarwal, Alba, Armstrong, Armstrong, Ashwell, Ashwell, Back, Bailey, Bos, Bos, Briggs, Briggs, Bueno, Bäckvall, Chemla, Christopher Meadows, Clark, Craig, Craig, Culvenor, David H. Grayson, El-Awa, Evans, Evans, Evans, Evans, Evans, Evans, Fernandez de la Pradilla, Fernandez de la Pradilla, Fernandez de la Pradilla, Fernandez de la Pradilla, Fernandez de la Pradilla, Forristal, Frank W. Lewis, Garrabou, Gnas, Gordon Hill, Hernandez, Hewkin, Jackson, Jackson, Jackson, Jackson, Jackson, Jackson, Jackson, Kurt Dolence, Lacour, Lacour, Langlois, Lewis, Lewis, Li, Liu, Llamas, Magnus, Mauleon, McLaughlin, Meggers, Meth-Cohn, Milen, Mori, Mosse, Moure, Narasimha Rao, Nishide, Node, Oppolzer, Pellissier, Pinho e Melo, Pinho e Melo, Polywka, Roos, Satoh, Shu, Simpkins, Solladié-Cavallo, Solladié-Cavallo, Sulzer-Mosse, Toru, Trost, Tsogoeva, Van Rheenen, Weitz, Wessel, Yoo, Zhu, Zwanenburg   +91 more
core   +1 more source

Total Syntheses of the Proposed Structure of Iriomoteolide-1a, -1b and Synthesis of Three Derivatives for Structural Studies

Marine Drugs, 2022
Iriomoteolide-1a and iriomoteolide-1b are very potent cytotoxic agents, isolated from marine dinoflagellates. We carried out the enantioselective syntheses of the proposed structures of these natural products.
Arun K. Ghosh, Hao Yuan
doaj   +1 more source

Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis [PDF]

, 2015
The authors acknowledge the EPSRC and Cancer Research UK (CRUK Grant No. C21383/A6950) for funding this research.Recent reports have highlighted the biological activity associated with a sub-family of the tetramic acid class of natural products.
Healy, Alan, Izumikawa, Miho, Shin-ya, Kazuo, Slawin, Alexandra Martha Zoya, Westwood, Nicholas James   +4 more
core   +1 more source

Raistrickiones A−E from a Highly Productive Strain of Penicillium raistrickii Generated through Thermo Change

Marine Drugs, 2018
Three new diastereomers of polyketides (PKs), raistrickiones A−C (1–3), together with two new analogues, raistrickiones D and E (4 and 5), were isolated from a highly productive strain of Penicillium raistrickii, which was subjected to an ...
De-Sheng Liu, Xian-Guo Rong, Hui-Hui Kang, Li-Ying Ma, Mark T. Hamann, Wei-Zhong Liu   +5 more
doaj   +1 more source

Asymmetric Electrophilic alpha-Amidoalkylation, VII1): Generation, Crystal Structure, and Trapping Reactions of a Chiral 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline Derived N-Acyliminium Ion [PDF]

, 1990
The camphanic acid amide 4 has efficiently been oxidized with triphenylcarbenium tetrafluoroborate (3) to yield the chiral N-acyliminium ion 1. Trapping reactions of 1 with the silyl nucleophiles 7a-c and 10a-f proceeded with stereoselective bond ...
Aledesanmi, Brossi, Brossi, Huber, Kametani, Nagasaka, Onda, Palasz, Shono, Stupnikova, Wanner, Wanner, Wanner, Wanner, Yamato, Zaugg   +15 more
core   +1 more source

Total Synthesis and Structural Revision of the Alkaloid Incargranine B [PDF]

, 2013
Seeing double: Consideration of the biosynthetic origins of incargranineB, which was originally assigned an unprecedented indolo[1.7]naphthyridine structure, led to the proposal of a dipyrroloquinoline framework as a more biosynthetically feasible ...
Bates, Brown, Drew, Green, Hase, Nicolaou, Shen, Su, Zimmermann   +8 more
core   +1 more source

Preparative thin-layer and column chromatography of prostaglandins

Journal of Lipid Research, 1969
Analytical and preparative chromatographic methods for monounsaturated prostaglandins are described. The systems were developed specifically for separation of the various hydroxy epimers of prostaglandin E1 and F1 but also offer superior separations for ...
Niels H. Andersen
doaj   +1 more source

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]

, 2017
Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E, Hudson, Brandi M, Romo, Daniel, Tantillo, Dean J   +3 more
core   +2 more sources

A Novel Bis(phosphido)pyridine [PNP]^(2−) Pincer Ligand and Its Potassium and Bis(dimethylamido)zirconium(IV) Complexes [PDF]

, 2010
A novel PNP bis(secondary phosphine)pyridine pincer ligand, 2,6-bis(2-(phenylphosphino)phenyl)pyridine, has been prepared in high yield, and the properties of the doubly deprotonated form as a ligand in K_4(PNP)_2(THF)_6 and (PNP)Zr(NMe_2)_2 have been ...
Bercaw, John E., Winston, Matthew S.
core   +2 more sources