Results 11 to 20 of about 20,067 (277)

Antifreeze glycopeptide diastereomers [PDF]

Beilstein Journal of Organic Chemistry, 2012
Antifreeze glycopeptides (AFGPs) are a special class of biological antifreeze agents, which possess the property to inhibit ice growth in the body fluids of arctic and antarctic fish and, thus, enable life under these harsh conditions. AFGPs are composed
Lilly Nagel, Carsten Budke, Axel Dreyer, Thomas Koop, Norbert Sewald   +4 more
doaj   +5 more sources

Separation and Bioactive Assay of 25R/S-Spirostanol Saponin Diastereomers from Yucca schidigera Roezl (Mojave) Stems [PDF]

Molecules, 2018
In order to find a simple, generic, efficient separation method for 25R/S-spirostanol saponin diastereomers, the liquid chromatographic retention behaviors of C12 carbonylation and C12 unsubstituted 25R/S-spirostanol saponin diastereomers on different ...
, Song Wu, Peijian Huang
exaly   +4 more sources

Diastereomers of Spheroidal Form and Commercially Available Taxifolin Samples [PDF]

Scientia Pharmaceutica
Taxifolin is a natural polyphenol belonging to the class of flavonoids. The structure of this compound is characterized by the presence of two chiral centers. The spheroidal form of taxifolin (TAXs) has emerged as a promising modification due to enhanced
Roman P. Terekhov, Evgeny S. Melnikov, Ilya D. Nikitin, Margarita A. Tokareva, Tatyana A. Rodina, Anastasiya D. Savina, Denis I. Pankov, Anastasiya K. Zhevlakova, Vladimir L. Beloborodov, Irina A. Selivanova   +9 more
doaj   +2 more sources

Excited States Symmetry Breaking and In-Plane Polarization Cause Chiral Reversal in Diastereomers [PDF]

Molecules, 2021
In this work, we investigate the electronic transitions and chirality of three isomers of huge conjugated systems: asymmetric diastereomers (MMMM) and two symmetrical diastereomers (PMPM and PPMM).
Chenglong Wang, Jingang Wang, Chunyang Wang   +2 more
doaj   +2 more sources

Field-Induced Diastereomers for Chiral Separation [PDF]

Physical Review Letters, 2019
Published by APS, College Park, Md.
Andrey Yachmenev, Jolijn Onvlee, Emil Zak, Alec Owens, Jochen Küpper   +4 more
openaire   +8 more sources

Mass–Energy Profiles Obtained by Quantum Chemical Computing Applied in Mass Spectrometry: A Case Study with Identification of a Group of Acetalized Monosaccharide Isomers

Applied Sciences, 2023
Accurate modeling of small molecules substantially reduces the logistical effort and time consumption to discover and then obtain chemicals with various applications.
Carolina Cojocariu, Nicolae Dinca, Marius Georgescu, Eugen Sisu, Alina Serb, Mihai-Cosmin Pascariu   +5 more
doaj   +1 more source

Structure–Activity Relationships of the Antimalarial Agent Artemisinin 10. Synthesis and Antimalarial Activity of Enantiomers of rac-5β-Hydroxy-d-Secoartemisinin and Analogs: Implications Regarding the Mechanism of Action

Molecules, 2021
An efficient synthesis of rac-6-desmethyl-5β–hydroxy-d-secoartemisinin 2, a tricyclic analog of R-(+)-artemisinin 1, was accomplished and the racemate was resolved into the (+)-2b and (−)-2a enantiomers via their Mosher Ester diastereomers.
Mohamed Jahan, Francisco Leon, Frank R. Fronczek, Khaled M. Elokely, John Rimoldi, Shabana I. Khan, Mitchell A. Avery   +6 more
doaj   +1 more source

Screening of Novel Antimicrobial Diastereomers of Azithromycin–Thiosemicarbazone Conjugates: A Combined LC-SPE/Cryo NMR, MS/MS and Molecular Modeling Approach

Antibiotics, 2022
A well-known class of antibacterials, 14- and 15-membered macrolides are widely prescribed to treat upper and lower respiratory tract infections. Azithromycin is a 15-membered macrolide antibiotic possessing a broad spectrum of antibacterial potency and ...
Iva Habinovec, Ivana Mikulandra, Paula Pranjić, Saša Kazazić, Hana Čipčić Paljetak, Antun Barišić, Branimir Bertoša, Mirjana Bukvić, Predrag Novak   +8 more
doaj   +1 more source

The Chemical and Pharmacological Properties of Mitragynine and Its Diastereomers: An Insight Review

Frontiers in Pharmacology, 2022
Mitragynine, is a naturally occurring indole alkaloid that can be isolated from the leaves of a psychoactive medicinal plant. Mitragyna speciosa, also known as kratom, is found to possess promising analgesic effects on mediating the opioid receptors such
Thiruventhan Karunakaran, Thiruventhan Karunakaran, Kok Zhuo Ngew, Kok Zhuo Ngew, Ahmad Alif Danial Zailan, Vivien Yi Mian Jong, Mohamad Hafizi Abu Bakar   +6 more
doaj   +1 more source

Asymmetric synthesis of α-alkylated carbonyl compounds and their biological applications [PDF]

Delta Journal of Science, 2022
Creation of asymmetric centers is the fundamental basis of asymmetric synthesis as the resulting diastereomers or enantiomers are formed in unequal ratio.
Hamada. S. A. S. A. Mandour, Adel I. Selim, Mariam Ezzat, Ahmed A. Noser   +3 more
doaj   +1 more source