Results 81 to 90 of about 20,067 (277)
Evaluation of chlorofusin, its seven chromophore diastereomers, and key analogues [PDF]
, 2009 Chlorofusin, its seven chromophore diastereomers, and key analogues were comparatively examined for inhibition of MDM2–p53 binding revealing that the chromophore, but not simple replacements, contributes significantly to the natural products properties ...
Lee, Sang Yeul +9 more
core +1 more source
The synthesis of the 2,3-difluorobutan-1,4-diol diastereomers
Beilstein Journal of Organic Chemistry, 2017 The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2,3-difluorobutane-1,4-diol, as well as the synthesis of the ...
Robert Szpera +4 more
doaj +1 more source
Determining the Extent of Biodegradation of Fuels Using the Diastereomers of Acyclic Isoprenoids [PDF]
, 2016 Improved testing and remediation procedures for sites contaminated with petroleum hydrocarbons are a priority in remote cold regions such as Antarctica, where costs are higher and remediation times are longer. Isoprenoid/n-alkane ratios are commonly used
Susan H. Ferguson (2498431) +6 more
core +1 more source
Photogenerated Oxetanes as a Gateway to Uphill Cyclopropanation
Angewandte Chemie International Edition, EarlyView.An atom‐economical route to densely functionalized cyclopropanes from furans and photochemically activated aldehydes is enabled by a unique oxetane‐to‐cyclopropane rearrangement. These cyclopropanes can be used to access complex bioactive scaffolds and serve as a platform for asymmetric cyclopropane synthesis.
Tim Köglmeier +2 more
wiley +1 more source
Conformation and Permeability: Cyclic Hexapeptide Diastereomers
Journal of Chemical Information and Modeling, 2019 Conformational ensembles of eight cyclic hexapeptide diastereomers in explicit cyclohexane, chloroform, and water were analyzed by multicanonical molecular dynamics (McMD) simulations. Free-energy landscapes (FELs) for each compound and solvent were obtained from the molecular shapes and principal component analysis at T = 300 K; detailed analysis of ...
Satoshi Ono +5 more
openaire +3 more sources
Synthesis of a new type of antitumour agent panaxytriol: synthesis of its four diastereomers [PDF]
, 1999 Synthesis of four diastereomers of panaxytriol has been described. The basic objective is to create two acetylenic precursors followed by cuprous chloride mediated C-C coupling ...
Sylesh Kumar, V. +2 more
core +1 more source
BioResources, 2015 Studying the stereochemistry of lignin as a natural chiral polymer may have scientific and technical importance regarding the behavior of lignin and delignification processes.
Mahnaz Oghbaie +2 more
doaj +1 more source
Analysis of L- and D-Amino Acids Using UPLC
Bio-Protocol, 2014 With the exception of glycine, α-amino acids are optically active, and two optical isomers (L- and D-) of each amino acid can be formed. Recent developments of analytical techniques have revealed that several free D-amino acids such as D-aspartate, D ...
Yuta Mutaguchi, Toshihisa Ohshima
doaj +1 more source
Unified Total Synthesis of Pteriatoxins and Their Diastereomers [PDF]
, 2016 A unified total synthesis is reported to access all of the possible diastereomers of pteriatoxins A−C, with the use of an intramolecular Diels−Alder reaction as the key step to form the carbo-macrocyclic core structure. The C34/C35-diol protecting groups
Scott S. Harried (2025583) +5 more
core +1 more source
Synthesis of phosphatidylcholine analogs with an alkyl group at C1 or C3 of the glycerol moiety.
Journal of Lipid Research, 1985 The syntheses of 1,2-di-(O-hexadecyl)-rac-glycero-3-phosphocholines containing a methyl group at either C1 or C3 of the glycerol moiety are described. The methyl group was introduced at C1 in a synthetic scheme beginning with the hydroxylation of methyl ...
N M Witzke, R Bittman
doaj +1 more source