Results 141 to 150 of about 19,176 (260)

Stereoselective, borane-catalysed synthesis of <i>syn</i>-β-hydroxyketones from α,β-unsaturated ketones. [PDF]

Chem Sci
Macleod J, Nimmo AJ, Cockcroft JHP, Dominguez-Molano P, Nichol GS, Thomas SP.   +5 more
europepmc   +1 more source

Truncation of Samroiyotmycin: Tailored seco‐Acids as Novel Antimalaria Compounds

European Journal of Organic Chemistry, Volume 29, Issue 34, 11 September 2026.
Six truncated samroiyotmycin‐derived antimalarials were synthesized by replacing the tosyloxazole unit with electron‐deficient aryl groups. The most active seco‐acid with EWG = 2 × CF3 outperformed the natural product SamA. Its enhanced activity supports a donor–acceptor interaction involving the electron‐poor aryl unit, consistent with inhibition of ...
Anton Czuczkowski, Anja Schäfer, Juliana A. Hüther, Bianca Wank, Robert Toews, Fotios Fotakis, Andreas Köhn, Markus Rehm, Matthias Rottmann, Anna Zens, Sabine Laschat   +10 more
wiley   +1 more source

Enhancing Diastereoselectivity of l‑Threonine Aldolase by Strengthening Kinetic Control To Mitigate Thermodynamic Equilibrium. [PDF]

Chem Bio Eng
Zheng W, Fang S, Zhu C, Yang L, Meng Y, Yang L, Wu J.   +6 more
europepmc   +1 more source

Substrate-Induced Diastereoselectivity in Rhodium-Catalyzed Hydroformylation

The object of this Ph.D. thesis is an investigation on the substrate-controlled diastereoselectivity in rhodium-catalyzed hydroformylation of open-chain chiral substrates.
Rocchiccioli, Silvia
core  

Planar Chirality Directs Enantiospecific Diastereoselectivity in Isocyanide-Based Multicomponent Reactions. [PDF]

ACS Org Inorg Au
Kapsalis M, Fragkiadakis M, Konstantaras I, Froudas KG, Stergiannakos T, Sun R, Benedetti E, Neochoritis CG.   +7 more
europepmc   +1 more source

Variable diastereoselectivity in acylation of 2-substituted cyclohexanols

, 2011
The ratio of diastereomeric products A and B in acylation of 2-substituted cyclohexanols was found to depend dramatically on the nature of substituents, solvent and additives. Unusual inversion of diastereoselectivity upon change of a solvent or addition
Visser, Jasper
core  

Light-Driven Epimerization: Diastereoconvergent Synthesis of [¹²C, ¹³C] β^2,3-Amino Acids. [PDF]

Angew Chem Int Ed Engl
Zhang L, Sun Y, Yu H, Zhu Y, Zhai R, Li P, Yang P, Tang B.   +7 more
europepmc   +1 more source

Sulfur Ylide-Mediated [2 + 1] Annulation for the Synthesis of Spiro[cyclopropane-indolizine] Derivatives. [PDF]

ACS Omega
Li ZY, Ma YN, Zheng X, Li T, Yuan M, Jiang L, Yuan M.   +6 more
europepmc   +1 more source

Inductive Diastereoselective Rationale for a Catalytic Strategy to Build Densely Chiral Five-Membered Carbocycles. [PDF]

JACS Au
Arenas-Baeza CM, Rivera-Chao E, Dominguez-Molano P, Chaves-Pouso A, Carbó JJ, Fañanás-Mastral M, Fernández E.   +6 more
europepmc   +1 more source

A Novel Class of “Super‐Strained” Spiro Heterocycles: Gateway to 1‐Azaspiro[3.3]heptane Derivatives, and Biological Validation

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho, Annarita Vicenti, Marco Colella, Francesco Pasca, Giuseppe Romanazzi, Mauro Niso, Carmen Abate, Ernesto Mesto, Emanuela Schingaro, Renzo Luisi   +9 more
wiley   +2 more sources