Strategies for Enantioselective, Cascade, Valorizing, and Expanded Heterocyclic Piancatelli Rearrangements. [PDF]
K ATG, Kizirian M, Picazo E.
europepmc +1 more source
This review presents the visible‐light‐mediated photochemical reaction for the synthesis of aza, oxa, and aza–oxa spirocyclic compounds via photoinduced electron transfer (PET), hydrogen atom transfer (HAT), single‐electron transfer (SET), or energy transfer (EnT) pathways.
Annu Bhardwaj +4 more
wiley +1 more source
Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles
Saturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Arthur Despois, Nicolai Cramer
wiley +2 more sources
Mechanochemical Diastereoselective Substrate-Directed Synthesis of Pyrrole-Isoxazolidines via 1,3-Dipolar Cycloaddition of Maleimides with Nitrones. [PDF]
de Jesus IS +4 more
europepmc +1 more source
A mild, metal‐free photochemical decarboxylative allylic alkylation protocol using inexpensive thioxanthone under blue LEDs couples diverse carboxylic and N‐protected amino acids with Morita–Baylis–Hillman derivatives, offering broad substrate scope and a mechanism supported by radical‐trapping experiments.
Areti N. Karamitrou +3 more
wiley +1 more source
Excitation of acyclic trisubstituted alkenes via triplet energy transfer for diastereo- and enantioselective [2 + 2] photocycloaddition. [PDF]
Long J +5 more
europepmc +1 more source
N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions
Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero +8 more
wiley +1 more source
Fragmentation of Vancoresmycin Reveals a Strong Dependence on Global Molecular Architecture for Antibacterial Activity. [PDF]
Schönenbroicher M +8 more
europepmc +1 more source
A stereodivergent route from D‐mannitol enables access to enantiopure C5‐α‐substituted linezolid analogues with full configurational control. Biological evaluation reveals that α‐substitution abolishes antibacterial activity irrespective of stereochemistry, establishing a strict steric limitation at C5 and highlighting the dominant role of substituent ...
José A. Gálvez +3 more
wiley +1 more source
Phosphine-Catalyzed Unsymmetric [2 + 2] Annulation of Allenyl Phosphonates for Highly Substituted Cyclobutenes. [PDF]
Sun SH +6 more
europepmc +1 more source

