Results 71 to 80 of about 52,165 (246)
Angewandte Chemie International Edition, Volume 64, Issue 36, September 1, 2025.Stereochemically defined inositol pyrophosphate isomers (PP‐InsP4) were synthesized and assigned by NMR spectroscopy using a chiral solvating agent. In the form of isotopically labeled standards, they were applied in CE‐MS‐based profiling of plant extracts and kinase assays, enabling structural reassignment and functional insight into enzymatic ...
Kevin Ritter +6 more
wiley +1 more source
A Stochastic Description of Dictyostelium Chemotaxis
PLoS ONE, 2012 Chemotaxis, the directed motion of a cell toward a chemical source, plays a key role in many essential biological processes. Here, we derive a statistical model that quantitatively describes the chemotactic motion of eukaryotic cells in a chemical gradient.
Amselem, Gabriel +4 more
openaire +7 more sources
An anatomy ontology to represent biological knowledge in
BMC Genomics, 2008 Background Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction.
Fey Petra +3 more
doaj +1 more source
Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. [PDF]
, 1991 The structure of rat liver vault ribonucleoprotein particles was examined using several different staining techniques in conjunction with EM and digestion with hydrolytic enzymes.
Chugani, DC +3 more
core +2 more sources
Self‐supervised denoising for medical imaging enhancement
BMEMat, Volume 3, Issue 3, September 2025.Optical microscopy is a fundamental tool of clinical imaging. AI‐driven self‐supervised denoising techniques enhance optical microscopy imaging, enabling high‐resolution long‐term tracking of in vivo and in vitro cells with minimal photodamage. This breakthrough improves clinical tools for molecular tracking, protein interaction studies, and drug ...
Guoxun Zhang, Yuanyuan Wei, Ho‐Pui Ho
wiley +1 more source
Recent Advances in CRISPR/Cas9-Mediated Genome Editing in Dictyostelium
Cells, 2019 In the last 30 years, knockout of target genes via homologous recombination has been widely performed to clarify the physiological functions of proteins in Dictyostelium.
Tetsuya Muramoto +3 more
doaj +1 more source
PLoS ONE, 2020 Cell-substrate adhesion of the social amoeba Dictyostelium discoideum, a model organism often used for the study of chemotaxis, is non-specific and does not involve focal adhesion complexes.
Richa Karmakar +7 more
doaj +1 more source
Developmental Dynamics, Volume 254, Issue 9, Page 1055-1067, September 2025.Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters +5 more
wiley +1 more source
Different Heterotrimeric G Protein Dynamics for Wide-Range Chemotaxis in Eukaryotic Cells
Frontiers in Cell and Developmental Biology, 2021 Chemotaxis describes directional motility along ambient chemical gradients and has important roles in human physiology and pathology. Typical chemotactic cells, such as neutrophils and Dictyostelium cells, can detect spatial differences in chemical ...
Yoichiro Kamimura +3 more
doaj +1 more source
A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains
The FEBS Journal, Volume 292, Issue 17, Page 4477-4486, September 2025.Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley +1 more source