Results 41 to 50 of about 980 (147)

Dieckol-Attenuated High-Fat Diet Induced Muscle Atrophy by Modulating Muscular Deposition of Lipid Droplets

, 2021
An excessive fat diet induces intramuscular fat deposition that accumulates as a form of lipid droplet (LD) and leads to lipotoxicity, including muscle atrophy or decreasing muscle strength.
Myeongjoo Son, Seung Eon Oh, Chul-Hyun Park, Kyung-A Byun, Kyunghee Byun, Seyeon Oh, Kuk Hui Son   +6 more
core   +1 more source

ED Formula, a Complex of Ecklonia cava and Chrysanthemum indicum, Ameliorates Airway Inflammation in Lipopolysaccharide-Stimulated RAW Macrophages and Ovalbumin-Induced Asthma Mouse Model

Pharmaceuticals, 2023
Ecklonia cava (E. cava) and Chrysanthemum indicum Linne (C. indicum) are natural raw materials known to have beneficial effects on inflammatory-related diseases, as evidenced by various sources in the literature.
Hyun Kang, Chan-Hwi Park, Sang-Oh Kwon, Sung-Gyu Lee   +3 more
doaj   +1 more source

Investigating the Potential Anti-Alzheimer’s Disease Mechanism of Marine Polyphenols: Insights from Network Pharmacology and Molecular Docking

Marine Drugs, 2023
Marine polyphenols, including eckol(EK), dieckol(DK), and 8,8’-bieckol(BK), have attracted attention as bioactive ingredients for preventing Alzheimer’s disease (AD).
Kumju Youn, Chi-Tang Ho, Mira Jun
doaj   +1 more source

Ecklonia cava Extract and Dieckol Attenuate Cellular Lipid Peroxidation in Keratinocytes Exposed to PM10 [PDF]

, 2018
Airborne particulate matter can cause oxidative stress, inflammation, and premature skin aging. Marine plants such as Ecklonia cava Kjellman contain high amounts of polyphenolic antioxidants.
Jin Kyung Seok, Jeong-won Lee, Yong Chool Boo   +2 more
core   +1 more source

Novel computational and drug design strategies for inhibition of monkeypox virus and Babesia microti: molecular docking, molecular dynamic simulation and drug design approach by natural compounds

Frontiers in Microbiology, 2023
BackgroundThe alarming increase in tick-borne pathogens such as human Babesia microti is an existential threat to global public health. It is a protozoan parasitic infection transmitted by numerous species of the genus Babesia.
Shopnil Akash, Showkat Ahmad Mir, Sajjat Mahmood, Saddam Hossain, Md. Rezaul Islam, Nobendu Mukerjee, Binata Nayak, Hiba-Allah Nafidi, Yousef A. Bin Jardan, Amare Mekonnen, Mohammed Bourhia   +10 more
doaj   +1 more source

The Effectiveness of Ecklonia Cava Kjellman Extract in Improving Menopausal Syndrome in Osteoporosis and Depression

Applied Sciences, 2021
Ecklonia cava (EC) is a natural material commonly used to decrease swelling, allergy, cancer, and sleep issues. Using EC has been reported to regulate hormones during ovarian failure in an aromatase inhibition rodent model.
Hyun Yang, Hye Jin Kim, Hye Won Lee
doaj   +1 more source

Molecular docking studies of a phlorotannin, dieckol isolated from Ecklonia cava with tyrosinase inhibitory activity

, 2012
In this study, the phlorotannin dieckol, which was isolated from the brown alga Ecklonia cava, was examined for its inhibitory effects on melanin synthesis. Tyrosinase inhibitors are important agents for cosmetic products.
Jeon, You-Jin, Kil-Nam Kim, Seung-Hong Lee, Kang, Sung-Myung, Lee, Seung-Hong, Yang, Hae-Mi, Kim, Areum-Daseul, Hae-Mi Yang, Soo-Jin Heo, Sung-Myung Kang, Kim, Kil-Nam, Areum-Daseul Kim, You-Jin Jeon, Heo, Soo-Jin   +13 more
core   +1 more source

2/cyclin E in response to p21/p53 activation in human tracheal fibroblasts

, 2022
The phlorotannin derivative dieckol isolated from Ecklonia cava has been shown to exhibit anti-inflammatory, anti-bacterial, anti-oxidative anti-adipogenic and anti-stenosis activity.
Jung, Won-Kyo, Won‐Kyo Jung, Hyoung Shin Lee, Choi, Il-Whan, Yi, Myunggi, Myunggi Yi, Jeong, Min-Seon, Min‐Seon Jeong, Won Sun Park, Heo, Seong-Yeong, Seong‐Yeong Heo, Lee, Hyoung Shin, Il‐Whan Choi, Park, Won Sun   +13 more
core   +1 more source

Dieckol fromEcklonia cavaRegulates Invasion of Human Fibrosarcoma Cells and Modulates MMP-2 and MMP-9 Expression via NF-κB Pathway [PDF]

, 2011
The matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix in normal physiological processes, as well as in the disease processes such as arthritis and cancer metastasis. In the present study, dieckol was obtained with
Chen Zhang, Zhong-Ji Qian, Se-kwon Kim, Yong-Xin Li, Sang-Hoon Lee, Yong Li   +5 more
core   +1 more source

Rethinking Alzheimer's Disease Therapy: From Amyloid‐Centric Approaches to Multi‐Target Phytochemical Strategies

Journal of Neurochemistry, Volume 170, Issue 7, July 2026.
Alzheimer's disease is driven by interconnected pathological processes, including amyloid‐β aggregation, tau hyperphosphorylation, neuroinflammation, oxidative stress, synaptic dysfunction, and mitochondrial impairment. While recently approved anti‐amyloid therapies represent an important advance, their modest clinical benefits highlight the ...
Emre Aktaş, İlay Yurt, Yağmur Nisa Cerlet, Haşmet Ayhan Hanağası   +3 more
wiley   +1 more source