Results 51 to 60 of about 980 (147)

Dieckol Attenuated Glucocorticoid-Induced Muscle Atrophy by Decreasing NLRP3 Inflammasome and Pyroptosis

open access: yes, 2021
Dexamethasone (Dexa), frequently used as an anti-inflammatory agent, paradoxically leads to muscle inflammation and muscle atrophy. Receptor for advanced glycation end products (RAGE) and Toll-like receptor 4 (TLR4) lead to nucleotide-binding ...
Kukhui Son   +4 more
core   +1 more source

Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions

open access: yesSensory Neuroscience, Volume 2, Issue 2, June 2026.
ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang   +7 more
wiley   +1 more source

Development of a simple and miniaturized sandwich-like fluorescence polarization assay for rapid screening of SARS-CoV-2 main protease inhibitors

open access: yesCell & Bioscience, 2021
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible and has caused a pandemic named coronavirus disease 2019 (COVID-19), which has quickly spread worldwide.
Gangan Yan   +8 more
doaj   +1 more source

Efficacy and Safety of Ecklonia cava Kjellman Extract Complex in Respiratory Health: A Randomized, Double‐Blind, Placebo‐Controlled, Multicenter Clinical Trial

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
This study evaluated the efficacy and safety of Ecklonia cava Kjellman extract complex (EEC) in respiratory health through a randomized clinical trial. Compared to the placebo group, the EEC group showed significant improvements in breathlessness, cough, and sputum scale (BCSS) including total, breathlessness, and sputum scores, visual analogue scale ...
Seong‐Cheon Woo   +8 more
wiley   +1 more source

From Sea to Sweet: Seaweed's Role in Nutritious and Sustainable Confectionery

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT Seaweed is increasingly recognized as a multifunctional ingredient in confectionery products, owing to its exceptional nutritional profile, functional properties, and environmental sustainability. This review highlights the integration of seaweed and seaweed‐derived compounds into a wide range of confectioneries, including chocolates, puddings,
Nima Mohammadi, Nikoo Ostovar
wiley   +1 more source

Antibacterial activity of the phlorotannins dieckol and phlorofucofuroeckol-A from Ecklonia cava against Propionibacterium acnes

open access: yesBotan‪ical Sciences, 2014
Methanol extract of the marine brown alga Ecklonia cava has been shown to exhibit antimicrobial activity against Propionibacterium acnes. To identify the compounds conferring this antimicrobial activity, methanol extract was fractionated using silica ...
Jae-Suk Choi   +7 more
doaj   +1 more source

Effect of Dieckol, a Component of Ecklonia cava, on the Promotion of Hair Growth

open access: yes, 2012
This study was conducted to evaluate the effect of Ecklonia cava, a marine alga native to Jeju Island in Korea, on the promotion of hair growth. When vibrissa follicles were cultured in the presence of E.
Eun-Sook Yoo   +8 more
core   +1 more source

Attenuating Effects of Dieckol on Hypertensive Nephropathy in Spontaneously Hypertensive Rats

open access: yes, 2021
Hypertension induces renal fibrosis or tubular interstitial fibrosis, which eventually results in end-stage renal disease. Epithelial-to-mesenchymal transition (EMT) is one of the underlying mechanisms of renal fibrosis.
Myeongjoo Son   +5 more
core   +1 more source

Nrf2 Activation in Inflammatory Diseases: A Review of Natural and Synthetic Modulators

open access: yesOxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
The nuclear factor erythroid 2–related factor 2 (Nrf2) pathway is a central regulator of the cellular antioxidant response, playing a key role in modulating inflammation and defending against oxidative stress‐induced damage. A range of natural and synthetic compounds, including dimethyl fumarate, bardoxolone, oltipraz, RTA‐408, ursodiol, curcumin ...
Vitória B. Costa   +6 more
wiley   +1 more source

Dieckol, an Algae-Derived Phenolic Compound, Suppresses UVB-Induced Skin Damage in Human Dermal Fibroblasts and Its Underlying Mechanisms

open access: yes, 2021
Ultraviolet (UV) irradiation is considered to be the primary environmental factor that causes skin damage. In the present study, we investigated the protective effect of dieckol (DK), a compound isolated from the brown seaweed Ecklonia cava, against UVB ...
Seungheon Lee   +4 more
core   +1 more source

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