Results 31 to 40 of about 1,721 (143)
Hormonal treatments for endometriosis (combined oral contraceptives/progestin‐only pills) do not show increased psychological or sexual risks compared with placebo. When pain is effectively controlled, these therapies appear well tolerated and may improve overall well‐being.
Noemi Salmeri +5 more
wiley +1 more source
ABSTRACT Purpose To clarify the efficacy and safety of the estetrol 15 mg/drospirenone 3 mg combination among Japanese women with adenomyosis by post hoc analyses of a previous randomized clinical study. Methods Post hoc analyses were performed using data from a 16‐week, multi‐center, randomized, double‐blinded, placebo‐controlled, parallel‐group study,
Tasuku Harada +7 more
wiley +1 more source
New ways in therapy of abnormal uterine bleedings related to adenomyosis [PDF]
The purpose of research was a comparison of the effect of a three-phase combined oral contraceptive (COC) containing estradiol valerate and dienogest in dynamic mode and single agent containing dienogest, to reduce menstrual blood loss on the background ...
N N Rukhliada +3 more
doaj
Background Hormonal intrauterine systems are widely used for long‐acting reversible contraception and for managing gynecological conditions such as heavy menstrual bleeding and endometrial hyperplasia. Although rare, complications such as uterine embedment and perforation can occur, potentially leading to device malfunction or injury displacement. This
Stefano Restaino +11 more
wiley +1 more source
Drug therapy efficacy for the syndrome of chronic pelvic pain relapses in perinatal endometriosis
Comparative analysis of drug therapy efficacy for the syndrome of chronic pelvic pain relapses in perinatal endometriosis has been presented: it included dienogest monotherapy and combined interleukin-2 (il-2) and dienogest therapy.
R. A. Musolyants +3 more
doaj
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye +11 more
wiley +1 more source
Background Dienogest has been shown to substantially improve endometriosis-associated symptoms such as debilitating chronic pelvic pain, and in turn, health-related quality of life (HRQoL).
Kitirat Techatraisak +9 more
doaj +1 more source
Objective: Long-term administration of dienogest, which is known to have effect on bone mineral density, is frequently done in patients with endometriosis and adenomyosis, but a few studies focused on the bone mineral density changes after finishing the ...
N Yamamoto +8 more
doaj +1 more source
ABSTRACT This observational study investigated the potential influence of hormonal contraceptive (HC) use on selected hormonal biomarkers (estradiol, total testosterone, IGF‐1, cortisol, triiodothyronine, and leptin) that respond to diet and physical training–induced low energy availability (LEA).
Ritva Mikkonen +5 more
wiley +1 more source

