Results 61 to 70 of about 2,721,186 (311)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

CONFECTIONERY GOODS FOR HEALTHY DIET

Foods and Raw Materials, 2015
Confectionery goods are in great demand with different population groups, especially children both in Russia and other countries. This group of products can be considered as a convenient carrier of vital nutrients, the lack of which in the diet of the population in Russia, including preschoolers and school children is a serious problem.
Dorn, G., Savenkova, T., Sidorova, O., Golub, O.   +3 more
openaire   +3 more sources

Are a healthy diet and physical activity synergistically associated with cognitive functioning in older adults?

, 2016
OBJECTIVES: Previous research has demonstrated that being both physically active and adhering a healthy diet is associated with improved cognitive functioning; however, it remains unclear whether these factors act synergistically.
Nijholt, W, Willemke Nijholt, Visser, M; id_orcid, van der Schans, Cees, Jager-Wittenaar, H., J. S. M. Hobbelen, Jager-Wittenaar, H, Van der Schans, C. P., Hobbelen, J S M, M. Visser, Visser, M., C. P. Van Der Schans, van der Schans, C P, Nijholt, Willemke, Hobbelen, Hans, Nijholt, W., Jager, Harriët, Hobbelen, J. S. M., Visser, M, H. Jager-Wittenaar   +19 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Association of Pro-Healthy Diet Index and Non-Healthy Diet Index with Body Composition: Baseline Results from Cohort Study [PDF]

International Journal of Nutrition Sciences
Background: Various dietary patterns have different effects on the body composition of adults. This study investigated the association of pro-healthy diet index (PHDI) and non-healthy diet index (NHDI) with body composition in employees of Shiraz ...
Nafise Davoudzadeh, Seyed Jalil Masoumi, Mehran Nouri, Zahra Sohrabi   +3 more
doaj   +1 more source

The dietary habits of Maltese university students [PDF]

, 2011
Objective: The objective of this study was to explore university students’ perceived diet and related health practices and whether these varied by gender, faculty and year of course.
Cefai, Carmel, Camilleri, Liberato
core  

Designing the eatwell week: the application of eatwell plate advice to weekly food intake [PDF]

, 2013
<p>To develop a menu and resource to illustrate to consumers and health professionals what a healthy balanced diet looks like over the course of a week.</p> <p>Development and analysis of an illustrative 7 d ‘eatwell week’ menu to ...
Leslie, W.S., Comrie, F., Hankey, C.R., Lean, M.E.J.   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source