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Dietary Polyphenols, Inflammation, and Cancer
Nutrition and Cancer, 2009A considerable amount of evidence indicates that tumorigenesis is associated with inflammation. Nuclear factor-kappa B (NF-kappa B), a master regulator of infection and inflammation, has been identified as a key modulator in which inflammation could develop into cancer.
Weimin, Guo +2 more
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Vascular protection by dietary polyphenols
European Journal of Pharmacology, 2004Consumption of polyphenol-rich foods, such as fruits and vegetables, and beverages derived from plants, such as cocoa, red wine and tea, may represent a beneficial diet in terms of cardiovascular protection. Indeed, epidemiological studies demonstrate a significant inverse correlation between polyphenol consumption and cardiovascular risk.
Jean-Claude, Stoclet +6 more
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Dihydro-resveratrol—A potent dietary polyphenol
Bioorganic & Medicinal Chemistry Letters, 2010Dihydro-resveratrol (dihydro-R), a prominent polyphenol component of red wine, has a profound proliferative effect on hormone-sensitive tumor cell lines such as breast cancer cell line MCF7. We found a significant increase in MCF7 tumor cells growth rates in the presence of picomolar concentrations of this compound.
A. Gakh, Andrei +8 more
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Dietary polyphenols and mechanisms of osteoarthritis
The Journal of Nutritional Biochemistry, 2012Osteoarthritis is a condition caused in part by injury, loss of cartilage structure and function, and an imbalance in inflammatory and anti-inflammatory pathways. It primarily affects the articular cartilage and subchondral bone of synovial joints and results in joint failure, leading to pain upon weight bearing including walking and standing. There is
Chwan-Li, Shen +6 more
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ToxDP2 Database: Toxicity prediction of dietary polyphenols
Food Chemistry, 2022Polyphenols are bioactive substances that minimize the risk of a variety of chronic diseases. Exposure to polyphenol bioactive compounds in our diet has increased across the globe, with amplified expectations from consumers, industry, and regulators centered on the potential benefits and essential safety of these compounds.
Meetali, Sinha +4 more
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Anticancer Potential of Dietary Polyphenols
2018Numerous compounds found in dietary sources have been correlated to decreased cancer incidence, a statement endorsed by the National Cancer Institute and the American Institute for Cancer Research. These include but are in no way limited to: red wine, ginger, cauliflower, brussel sprouts, turmeric, onion, cabbage, soy bean, green tea, tomato, and ...
Amy L. Stockert, Matthew Hill
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Cancer Chemoprevention by Dietary Polyphenols
2014Cancer remains a major health problem and is one of the leading causes of deaths worldwide. It is a complex disease which can originate from several causes, and genome-wide association studies have indicated already the existence of several genetic variants that might contribute to the initiation or the progression of the disease.
Karen Heyninck, Guy Haegeman, Ajay Goel
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Cardiovascular Benefits of Dietary Polyphenols
2020Cardiovascular disease (CVD) affects millions of people worldwide, thereby warranting more effective therapeutic approaches. Epidemiological studies have highlighted that a lower incidence of CVD rate is associated with long-term consumption of plant-based diets rich in polyphenols. Many polyphenolic compounds have been purported to possess significant
Boon Hee Goh, Joash Ban Lee Tan
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