Results 61 to 70 of about 27,953 (293)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Active vibration control of vehicle suspension systems using sliding modes, differential flatness and generalized proportional-integral control

Revista Facultad de Ingeniería Universidad de Antioquia, 2012
This paper presents a design approach of robust active vibration control schemes for vehicle suspension systems using differential flatness, sliding modes and Generalized Proportional-Integral control techniques to attenuate undesirable vibrations ...
Esteban Chávez Conde, Francisco Beltrán Carbajal, Antonio Valderrábano González, Antonio Favela Contreras   +3 more
doaj   +1 more source

Geometry and flatness of m-crane systems [PDF]

Bulletin of the Polish Academy of Sciences: Technical Sciences, 2019
We propose a class of m-crane control systems, that generalizes two- and three-dimensional crane systems. We prove that each representant of the described class is feedback equivalent to the second order chained form with drift.
M. Nowicki, W. Respondek, J. Piasek, K. Kozłowski   +3 more
doaj   +1 more source

Computationally Efficient Trajectory Optimization for Linear Control Systems with Input and State Constraints

, 2012
This paper presents a trajectory generation method that optimizes a quadratic cost functional with respect to linear system dynamics and to linear input and state constraints.
Kennel, Ralph, Stumper, Jean-Francois
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

An Optimal Integrated Control Scheme for Permanent Magnet Synchronous Generator-Based Wind Turbines under Asymmetrical Grid Fault Conditions

Energies, 2016
In recent years, the increasing penetration level of wind energy into power systems has brought new issues and challenges. One of the main concerns is the issue of dynamic response capability during outer disturbance conditions, especially the fault ...
Dan Wang, Chongru Liu, Gengyin Li
doaj   +1 more source

Flatness‐based control for steam‐turbine power generation units using a disturbance observer

IET Electric Power Applications, 2021
Steam‐turbine power plants still supply a significant part of the electric power consumed worldwide. The viability of steam turbine power units depends on their efficiency to a great extent and the control method applied to the them is of major ...
Gerasimos Rigatos, Nikolaos Zervos, Pierluigi Siano, Patrice Wira, Masoud Abbaszadeh   +4 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Quadcopter Trajectory Tracking Control Based on Flatness Model Predictive Control and Neural Network

Actuators
In this paper, a novel control architecture is proposed in which FMPC couples feedback from model predictive control with feedforward linearization. The proposed approach has the computational advantage of only requiring a convex quadratic program to be ...
Yong Li, Qidan Zhu, Ahsan Elahi
doaj   +1 more source

Safe Learning of Quadrotor Dynamics Using Barrier Certificates

, 2017
To effectively control complex dynamical systems, accurate nonlinear models are typically needed. However, these models are not always known. In this paper, we present a data-driven approach based on Gaussian processes that learns models of quadrotors ...
Egerstedt, Magnus, Theodorou, Evangelos A., Wang, Li   +2 more
core   +1 more source