Results 71 to 80 of about 497,650 (279)

Flatness optimization of micro-injection moulded parts: The case of a PMMA microfluidic component [PDF]

, 2011
Micro-injection moulding (µ-IM) has attracted a lot of interest because of its potential for the production of low-cost, miniaturized parts in high-volume.
Alcock, Jeffrey R., Allen, David M., Attia, Usama M., Lucchetta, G., Marson, Silvia, Wilson, A.   +5 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Active vibration control of vehicle suspension systems using sliding modes, differential flatness and generalized proportional-integral control

Revista Facultad de Ingeniería Universidad de Antioquia, 2012
This paper presents a design approach of robust active vibration control schemes for vehicle suspension systems using differential flatness, sliding modes and Generalized Proportional-Integral control techniques to attenuate undesirable vibrations ...
Esteban Chávez Conde, Francisco Beltrán Carbajal, Antonio Valderrábano González, Antonio Favela Contreras   +3 more
doaj   +1 more source

Differential Flatness and Absolute Equivalence [PDF]

, 1995
In this paper we give a formulation of differential flatness---a concept originally introduced by Fleiss, Levine, Martin, and Rouchon---in terms of absolute equivalence between exterior differential systems.
Murray, Richard M., Rathinam, Muruhan, van Nieuwstadt, Michiel   +2 more
core   +1 more source

On the computation of $\pi$-flat outputs for differential-delay systems

, 2014
We introduce a new definition of $\pi$-flatness for linear differential delay systems with time-varying coefficients. We characterize $\pi$- and $\pi$-0-flat outputs and provide an algorithm to efficiently compute such outputs.
Antritter, F., Cazaurang, F., Lévine, J., Middeke, J.   +3 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Geometry and flatness of m-crane systems [PDF]

Bulletin of the Polish Academy of Sciences: Technical Sciences, 2019
We propose a class of m-crane control systems, that generalizes two- and three-dimensional crane systems. We prove that each representant of the described class is feedback equivalent to the second order chained form with drift.
M. Nowicki, W. Respondek, J. Piasek, K. Kozłowski   +3 more
doaj   +1 more source

Active Sensing Control for Differentially Flat Systems

IEEE Control Systems Letters
This paper proposes an optimal active perception strategy using the Constructibility Gramian (CG) as a metric to quantify the richness of the information acquired along the planned trajectory. A critical issue is the dependence of the CG on the transition matrix, whose closed-form expression is not available for most robotic systems while its numerical
Olga Napolitano, Annamaria Pinizzotto, Matteo Verdecchia, Alessio Pettinari, Daniela Selvi, Lucia Pallottino, Paolo Salaris   +6 more
openaire   +2 more sources

Feed-Forward river flow control using differential flatness [PDF]

2008 47th IEEE Conference on Decision and Control, 2008
The rarefaction of global water resources is a motivation for research on automation of management of water distribution systems. Large amounts of fresh water are lost due to poor management of open-channel systems. This article focuses on the management of such canals which are used to convey water from the resource (generally a dam located upstream ...
Di Meglio, Florent, Rabbani, T., Litrico, X., Bayen-Poisson, Aurélie   +3 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source