Results 71 to 80 of about 27,971 (292)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Accurate Tracking of Agile Trajectories for a Tail-Sitter UAV Under Wind Disturbances Environments

Drones
To achieve more robust and accurate tracking control of high maneuvering trajectories for a tail-sitter fixed-wing unmanned aerial vehicle (UAV) operating within its full envelope in outdoor environments, a novel control approach is proposed.
Xu Zou, Zhenbao Liu, Zhen Jia, Baodong Wang   +3 more
doaj   +1 more source

Assessment of Aerial Combat Game via Optimization-Based Receding Horizon Control

IEEE Access, 2020
This paper focuses on modeling of air-to-air combat via optimization-based control and game-theoretic approach. The flatness property of the dynamical system is used to present aircraft dynamics in terms of specific variables and their derivatives that ...
Baris Baspinar, Emre Koyuncu
doaj   +1 more source

Safe Learning of Quadrotor Dynamics Using Barrier Certificates

, 2017
To effectively control complex dynamical systems, accurate nonlinear models are typically needed. However, these models are not always known. In this paper, we present a data-driven approach based on Gaussian processes that learns models of quadrotors ...
Egerstedt, Magnus, Theodorou, Evangelos A., Wang, Li   +2 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Differential-Flatness and Control of Quadrotor(s) with a Payload Suspended through Flexible Cable(s)

, 2017
We present the coordinate-free dynamics of three different quadrotor systems : (a) single quadrotor with a point-mass payload suspended through a flexible cable; (b) multiple quadrotors with a shared point-mass payload suspended through flexible cables ...
Kotaru, Prasanth, Sreenath, Koushil, Wu, Guofan   +2 more
core   +1 more source

Differential Flatness Properties and Feedback Control of the Fokker–Planck PDE [PDF]

Intelligent Industrial Systems, 2016
The Fokker–Planck PDE describes the dynamics of several biochemical and biological processes, as well as of phenomena at molecular scale. In this paper, the problem of feedback control of the Fokker–Planck PDE is studied. It is shown that the procedure for numerical solution of Fokker–Planck PDE results into a set of nonlinear ordinary differential ...
Rigatos, Gerasimos, SIANO, PIERLUIGI, Melkikh, Alexey   +2 more
openaire   +3 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Active Sensing Control for Differentially Flat Systems

IEEE Control Systems Letters
This paper proposes an optimal active perception strategy using the Constructibility Gramian (CG) as a metric to quantify the richness of the information acquired along the planned trajectory. A critical issue is the dependence of the CG on the transition matrix, whose closed-form expression is not available for most robotic systems while its numerical
Olga Napolitano, Annamaria Pinizzotto, Matteo Verdecchia, Alessio Pettinari, Daniela Selvi, Lucia Pallottino, Paolo Salaris   +6 more
openaire   +2 more sources

A NEURAL NETWORK CONTROL BASED ON DIFFERENTIAL FLATNESS FOR A QUADROTOR [PDF]

Conferência Brasileira de Dinâmica, Controle e Aplicações, 2011
In this paper, a control strategy for a quadrotor using neural network and differential flatness is proposed. Since attitude and altitude of the quadrotor are differential flat outputs for its flight dynamics, neural networks are used to perform the inversion of the flight dynamics and provide the nominal input control for the quadrotor.
S. Cunha, Sebastião, Panomruttanarug, Benjamas, Al-Fazari, Hamdam, Mora-Camino, Felix   +3 more
openaire   +2 more sources