Results 91 to 100 of about 126,237 (291)

Microtranscriptome analysis of sugarcane cultivars in response to aluminum stress.

PLoS ONE, 2019
Although several metallic elements are required for plant growth, excessive amounts of aluminum ions (Al3+) can result in the inhibition of root growth, thus triggering water and nutrient deficiencies.
Renan Gonçalves da Silva, Thiago Mateus Rosa-Santos, Suzelei de Castro França, Pratibha Kottapalli, Kameswara Rao Kottapalli, Sonia Marli Zingaretti   +5 more
doaj   +1 more source

Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells [PDF]

, 2018
Indexación: Scopus.Departamento de Oncología Básico-Clínica, Facultad de Medicina, Universidad de Chile, Santiago, Chile 2Comisión Chilena de Energía Nuclear, Santiago, Chile 3Center for Research and Applications in Plasma Physics and Pulsed Power, P4 ...
Andaur, R., Armisen, R., Marcelain, K., Moreno, J., Soto, L., Tapia, J.C.   +5 more
core   +1 more source

Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing [PDF]

, 2020
Toll-like receptors (TLRs) belong to pattern recognition receptors, which respond to danger signals such as pathogen-associated molecular patterns or damage-associated molecular patterns.
Buonfiglioli, Alice, Dembny, Paul, Krüger, Christina, Lehnardt, Seija, Prinz, Marco, Staszewski, Ori, Wallach, Thomas, Wetzel, Max   +7 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

MicroRNA-Mediated Responses to Chromium Stress Provide Insight Into Tolerance Characteristics of Miscanthus sinensis

Frontiers in Plant Science, 2021
Chromium (Cr) is a heavy metal in nature, which poses a potential risk to toxicity to both animals and plants when releasing into the environment. However, the regulation of microRNA (miRNA)-mediated response to heavy metal Cr has not been studied in ...
Gang Nie, Zongchao Liao, Minyi Zhong, Jie Zhou, Jiabang Cai, Aiyu Liu, Xia Wang, Xinquan Zhang   +7 more
doaj   +1 more source

Identification of differentially expressed miRNAs in mouse spinal cord development [PDF]

Acta Biochimica et Biophysica Sinica, 2015
MicroRNAs (miRNAs) are a class of non-coding, regulatory small RNAs of ∼22 nt. It was implicated that these small RNAs play critical roles in various important biological processes. During development, some miRNAs are specifically expressed in individual tissues and at particular developmental stages.
Botao, Zhao, Menggui, Huang, Yanyan, Bai, Chunsun, Fan, Yi, Fan, Youxin, Jin   +5 more
openaire   +2 more sources

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

Microarray-based analysis reveals a novel role of the miRNA-613/SNAI2/CXCR4 axis in atrial fibrillation.

PLoS ONE
BackgroundsAtrial fibrillation (AF) can lead to substantial morbidity and mortality in clinic. The previous studies demonstrated that miRNAs were closely associated with several cardiovascular diseases, however, the role of miRNAs in the pathogenesis of ...
Zhenyu Zhai, Yiligong Qi, Longlong Hu, Zumao Gan   +3 more
doaj   +1 more source

Differentially expressed miRNAs in oxygen‑induced retinopathy newborn mouse models. [PDF]

Mol Med Rep, 2017
The present study aimed to identify microRNAs (miRNAs) involved in regulating retinal neovascularization and retinopathy of prematurity (ROP). A total of 80 healthy C57BL/6 neonatal mice were randomly divided into the oxygen‑induced retinopathy (OIR) group (n=40), in which 7‑day‑old mice were maintained in 75% oxygen conditions for 5 days, or the ...
Wang Y, Wu S, Yang Y, Peng F, Li Q, Tian P, Xiang E, Liang H, Wang B, Zhou X, Huang H, Zhou X.   +11 more
europepmc   +4 more sources

Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells [PDF]

, 2019
BACKGROUND: The pathology of juvenile dermatomyositis (JDM) is characterized by prominent vessel wall and perivascular inflammation. This feature of the disease has remained unexplained and under-investigated. We have hypothesized that plasma exosomes,
Chen, Yanmin, Holmes, Lucy, Hu, Zihua, Jarvis, James N., Jiang, Kaiyu, Karasawa, Rie, O’Neil, Kathleen M.   +6 more
core   +1 more source