Results 201 to 210 of about 126,237 (291)

Uncovering potential differentially expressed miRNAs and targeted mRNAs in myocardial infarction based on integrating analysis. [PDF]

Mol Med Rep, 2020
Wang S, Cao N.
europepmc   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Identification of differentially expressed miRNAs involved in vascular aging reveals pathways associated with the endocrine hormone regulation. [PDF]

Biogerontology
Jeon J, Jang S, Park KS, Kim HG, Lee J, Hwang TS, Koh JS, Kim J.   +7 more
europepmc   +1 more source

Genome-Wide Analysis of Differentially Expressed miRNAs and Their Associated Regulatory Networks in Lenses Deficient for the Congenital Cataract-Linked Tudor Domain Containing Protein TDRD7. [PDF]

Front Cell Dev Biol, 2021
Anand D, Al Saai S, Shrestha SK, Barnum CE, Chuma S, Lachke SA.   +5 more
europepmc   +1 more source

Dynamics of the association between circulating levels of miRNA and pancreatic cancer risk through the years prior to pancreatic cancer diagnosis

International Journal of Cancer, EarlyView.
What's New? Early diagnosis is critical for improving pancreatic ductal adenocarcinoma prognosis, but few biomarkers currently exist. In a case–control study of 1,307 pancreatic cancer cases and matched pairs nested in prospective cohort studies, 13 miRNA–cancer associations were found to change during the blood‐draw‐to‐diagnosis time window.
Hui Cai, Veronica Wendy Setiawan, Xingyi Guo, Jie Wu, Rachael Stolzenberg‐Solomon, Yu‐Tang Gao, Jordan Berlin, Fei Ye, Qiuyin Cai, Wei Zheng, Xiao‐Ou Shu   +10 more
wiley   +1 more source

DIFFERENTIALLY EXPRESSED MIRNAS EXPLAIN RACIAL DIFFERENCES IN DIAGNOSIS STAGE AMONG TRIPLE NEGATIVE BREAST CANCER PATIENTS IN LOUISIANA. [PDF]

J La Public Health Assoc
Hu Y, Wu X, Luo M, Rizvi N, Bam A, Del Valle L, Miele L, Yu Q.   +7 more
europepmc   +1 more source

The Growth Supporting Role of ZDHHC11 Is Linked to the MEF2B–BCL6 Regulatory Circuit in Burkitt Lymphoma

International Journal of Cancer, EarlyView.
MEF2B and BCL6 have established functions in germinal center B‐cell biology and lymphomagenesis. The mechanism of MEF2B deregulation and its significance for cell survival in Burkitt lymphoma however remain unclear. This study highlights MEF2B as a crucial transcription factor in Burkitt lymphoma and suggests ZDHHC11 as an upstream regulator of MEF2B ...
Lotteke J. Y. M. Ziel‐Swier, Karolina Rassek, Yichen Liu, Annika Seitz, Jasper Koerts, Debora de Jong, Bea Rutgers, Anastasiia Kompaniiets, Julia Przybył, Martine E. D. Chamuleau, Anke van den Berg, Agnieszka Dzikiewicz‐Krawczyk, Joost Kluiver   +12 more
wiley   +1 more source

Identification of differentially expressed miRNAs associated with diamide detoxification pathways in Spodoptera frugiperda. [PDF]

Sci Rep
Mahalle RM, Sun W, Posos-Parra OA, Jung S, Mota-Sanchez D, Pittendrigh BR, Seong KM.   +6 more
europepmc   +1 more source

Transcriptome‐Based Classification of Resected Pancreatic Ductal Adenocarcinoma Enhances Prognostic Modelling Accuracy of Overall Survival Following Adjuvant Treatment

International Journal of Cancer, EarlyView.
Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen, Vincent R. Lanting, Paul Manoukian, Marc G. Besselink, Geert Kazemier, Ignace H. J. T. de Hingh, Mike S. L. Liem, Casper H. J. van Eijck, Erwin van der Harst, Vincent E. de Meijer, Ronald M. van Dam, Martijn W. J. Stommel, Jan Koster, Michael W. T. Tanck, Arantza Fariña Sarasqueta, Joanne Verheij, Frederike Dijk, Johanna W. Wilmink, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven, for the Dutch Pancreatic Cancer Group   +20 more
wiley   +1 more source

Identification of differentially expressed miRNAs and mRNAs in synovial of osteoarthritis via RNA-sequencing. [PDF]

BMC Med Genet, 2020
Zhou Y, Wang Z, Chen X, Zhang J, Yang L, Liu S, Liu Y.   +6 more
europepmc   +1 more source