Results 261 to 270 of about 126,237 (291)

Integrated miRNA–mRNA Analysis Reveals Obesity‐Driven Regulatory Networks in Human Visceral Adipose Tissue With and Without Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Obesity is characterised by pathological alterations in visceral white adipose tissue (vWAT) that may contribute to the development of type 2 diabetes (T2D). While microRNAs (miRNAs) are key post‐transcriptional regulators, comprehensive human vWAT profiling across metabolic states remains limited.
Elsa Villa‐Fernández, Ana Victoria García, Laura Gallardo‐Nuell, Miguel García‐Villarino, Judit Fernández‐García, Aldara Martin Alonso, Claudia Lozano‐Aida, Lorena Suárez Gutiérrez, Pedro Pujante, Jessica Ares, Tomás González‐Vidal, Raquel Rodríguez Uría, Sandra Sanz Navarro, María Moreno Gijón, Lourdes María Sanz Álvarez, Estrella Olga Turienzo Santos, José Manuel Fernández‐Real, Mario Fernández Fraga, Elías Delgado, Carmen Lambert   +19 more
wiley   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Differentially expressed miRNAs in bone after methotrexate treatment

Journal of Cellular Physiology, 2021
AbstractPrevious studies have shown that administration of antimetabolite methotrexate (MTX) caused a reduced trabecular bone volume and increased marrow adiposity (bone/fat switch), for which the underlying molecular mechanisms and recovery potential are unclear.
Yali Zhang, Liang Liu, Katherine A Pillman, John Hayball, Yu‐Wen Su, Cory J. Xian   +5 more
openaire   +4 more sources

Differentially expressed miRNAs associated with generalized aggressive periodontitis

Clinical Oral Investigations, 2023
This study aimed to investigate miRNA expression profiles in individuals with periodontitis which is a chronic inflammatory condition affecting the integrity of the periodontal attachment. miRNAs play a crucial role in gene regulation through various mechanisms, making them potential diagnostic markers and therapeutic targets for various diseases.A ...
Sunnetci-Akkoyunlu, Deniz, Balta-Uysal, VECİHE MERVE, Özer, Tolgahan, Cine, Naci, Işik, Elif Büşra, Guzeldemir-Akcakanat, Esra   +5 more
openaire   +3 more sources

Differentially expressed miRNAs in retinoblastoma

Gene, 2013
MicroRNAs (miRNAs) are short non-coding RNA transcripts that have the ability to regulate the expression of target genes, and have been shown to influence the development of various tumors. The purpose of our study is to identify aberrantly expressed miRNAs in retinoblastoma for the discovery of potential therapeutic targets for this disease, and to ...
Joshua, Martin, Paul, Bryar, Marilyn, Mets, Joanna, Weinstein, Aunica, Jones, Alissa, Martin, Elio F, Vanin, Denise, Scholtens, Fabricio F, Costa, Marcelo B, Soares, Nikia A, Laurie   +10 more
openaire   +2 more sources

Differentially expressed miRNAs and potential therapeutic targets for asthenospermia

Andrologia, 2021
Asthenozoospermia is detected in 40% of infertile men, and characterised by low sperm motility. MicroRNAs (miRNAs) play essential roles in spermatogenesis, but little is known regarding the function of seminal plasma miRNAs in asthenozoospermia. In this study, we collected seminal plasma samples from patients with asthenospermia and healthy men and ...
Gaozhao Liang, Qianqian Wang, Guohui Zhang, Zhongxiang Li, Qing Wang   +4 more
openaire   +2 more sources

Differentially expressed miRNAs in trisomy 21 placentas.

Prenatal diagnosis, 2017
Molecular pathogenesis of Down syndrome (DS) is still incompletely understood. Epigenetic mechanisms, including miRNAs gene expression regulation, belong to potential influencing factors. The aims of this study were to compare miRNAs expressions in placentas with normal and trisomic karyotype and to associate differentially expressed miRNAs with ...
Iveta, Svobodová, Marie, Korabečná, Pavel, Calda, Miroslav, Břešťák, Eva, Pazourková, Šárka, Pospíšilová, Miroslava, Krkavcová, Michaela, Novotná, Aleš, Hořínek   +8 more
openaire   +2 more sources

Differential expression of gut miRNAs in idiopathic Parkinson's disease

Parkinsonism & Related Disorders, 2021
In the present work, we aimed to investigate the expression of microRNAs (miRNAs) in routine colonic biopsies obtained from patients with idiopathic Parkinson's disease (PD) and to address their value as a diagnostic biomarker for PD and their mechanistic contribution to PD onset and progression.Patients with PD (n = 13) and healthy controls (n = 17 ...
Anna Kurz, Rohit Kumar, Bernd H. Northoff, Catharina Wenk, Jörg Schirra, Sainitin Donakonda, Günter U. Höglinger, Johannes Schwarz, Verena Rozanski, Rainer Hübner, Kai Bötzel, Lesca Miriam Holdt, Thomas Koeglsperger   +12 more
openaire   +2 more sources

MiRNA expression profile and miRNA–mRNA integrated analysis (MMIA) during podocyte differentiation

Molecular Genetics and Genomics, 2014
The podocyte is a prominent cell type, which encases the capillaries of glomerulus. Podocyte-selective deletion of Dicer or Drosha was reported to induce proteinuria and glomerulosclerosis, suggesting the essential role of microRNA (miRNA) in podocytes for renal function.
Zhigui, Li, Lifeng, Wang, Jing, Xu, Zhuo, Yang   +3 more
openaire   +2 more sources

Differential expression of miRNA in histological subtype of Wilms tumor

Pediatric Surgery International, 2021
Wilms tumor is the most common renal malignancy in children and difficult to differentiate from other paediatric abdominal tumors radiologically, necessitating an invasive procedure for diagnosis. Previous studies have shown the potential role of miRNA as biomarkers for diagnosis, histological subtyping and prognosis.
Disha, Kakkar, Saumyaranjan, Mallick, Aijaz, Ahmad, Ansh, Goswami, Sandeep, Agarwala, Aditya Kumar, Gupta, V, Sreenivas, Sameer, Bakhshi, K, Devasenathipathy, Sandeep, Mathur, Deepali, Jain, Rachana, Seth, Venkateswaran K, Iyer   +12 more
openaire   +2 more sources

Differential miRNA expression between equine ovulatory and anovulatory follicles

Domestic Animal Endocrinology, 2013
Relatively little is known about the physiological roles of microRNAs (miRNAs) during follicular development. Previous evidence from in vitro studies suggests specific roles for a subset of miRNAs, including miR-21, miR-23a, miR-145, miR-503, miR-224, miR-383, miR-378, miR-132, and miR-212, in regulating ovarian follicle development.
F X, Donadeu, S N, Schauer
openaire   +2 more sources