Results 31 to 40 of about 18,251 (262)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Pearl millet utilization in ccommercial laying hen diets formulated on a total or digestible amino acid basis

Brazilian Journal of Poultry Science, 2005
An experiment was carried out to evaluate the effect of replacing corn with pearl millet in commercial layer diets, formulated according to the minimal requirements for total and digestible amino acids.
RS Filardi, OM Junqueira, EM Casartelli, AC Laurentiz, KF Duarte, V Assuena   +5 more
doaj   +1 more source

Nutritional components and protein quality analysis of genetically modified phytase maize

GM Crops & Food, 2022
The nutritional components and protein quality of genetically modified maize expressing phytase gene (GM) were analyzed and evaluated in this study. The nutritional components were analyzed by Chinese national standard methods.
Yichun Hu, Liqin Linghu, Min Li, Deqian Mao, Yu Zhang, Xiaoguang Yang, Lichen Yang   +6 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Protease Supplementation under Amino Acid Reduction in Diets Formulated with Different Nutritional Requirements for Broilers

Brazilian Journal of Poultry Science, 2019
This study aimed to evaluate the effect of different reductions in digestible amino acids content (lysine, methionine, and threonine), according to two nutritional requirements in corn, soybean meal, and meat and bone meal based diets, with protease ...
GV Dessimoni, FS Dalólio, J Moreira, LV Teixeira, AG Bertechini, RG Hermes   +5 more
doaj   +1 more source

Digestible lysine requirement for Tambaqui (Colossoma macropomum) juveniles using the diet dilution technique

Aquaculture Reports, 2020
This study aimed at determine the digestible lysine requirement of tambaqui juveniles using the diet dilution technique. A total of 250 juveniles tambaqui with an initial mean of 22.99 ± 1.06 g were used in a dose-response experiment with five levels of ...
Rafael Silva Marchão, Felipe Barbosa Ribeiro, Jefferson Costa de Siqueira, Marcos Antonio Delmondes Bomfim, Janayra Cardoso Silva, Thalles José Rêgo de Sousa, Daphinne Cardoso Nagib do Nascimento, Marilene da Costa Sousa   +7 more
doaj   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Different Levels of Digestible Methionine on Performance of Broiler Starter

Animal Production: Indonesian Journal of Animal Production, 2010
Dietary protein and amino acid supply is the most expensive component of poultry diets. Therefore several efforts made by the industry to minimize the cost of the protein portion of the diet.
WL Bryden, RL Ulrikus, NGA Mulyantini, X Li   +3 more
doaj  

Nutritional levels of digestible methionine + cystine to brown-egg laying hens from 50 to 66 weeks of age

Revista Brasileira de Zootecnia, 2012
The objective of this study was to determine the requirement of digestible methionine + cystine of brown-eggs laying hens from 50 to 66 weeks age at the end of the first production cycle.
Clauber Polese, Ricardo Vianna Nunes, Christiane Garcia Vilela, Márcia Antonia Bartolomeu Agustini, Sabrina Endo Takahashi, Valter Oshiro Vilela, Cleverson de Souza, Cândida Camila dos Reis   +7 more
doaj   +1 more source

Initial assessment of protein and amino acid digestive dynamics in protein-rich feedstuffs for broiler chickens.

PLoS ONE, 2020
A study evaluating apparent digestibilities of protein and amino acids and their corresponding digestion rates in four small intestinal sites in broiler chickens was completed to further investigate dietary optimisation via synchronised nutrient ...
M Toghyani, L R McQuade, B V Mclnerney, A F Moss, P H Selle, S Y Liu   +5 more
doaj   +1 more source