Results 91 to 100 of about 363,724 (308)

Assessment of Digestion and Absorption Properties of 1,3-Dipalmitoyl-2-Oleoyl Glycerol-Rich Lipids Using an In Vitro Gastrointestinal Digestion and Caco-2 Cell-Mediated Coupled Model

Molecules
The digestion and absorption properties of 1,3-dipalmitoyl-2-oleoyl glycerol (POP)-rich lipids was evaluated using in vitro gastrointestinal digestion and a Caco-2 cell-mediated coupled model.
Hyeon-Jun Chang, A-Young Lee, Jeung-Hee Lee   +2 more
doaj   +1 more source

Release of wheat gluten exorphins A5 and C5 during in vitro gastrointestinal digestion of bread and pasta and their absorption through an in vitro model of intestinal epithelium [PDF]

, 2015
Pasta and bread provide energy and nutrients, but they also may represent a potential source of dietary bioactive substances. In this regard, attention has been paid to the physiological and pathological role of the gluten-derived peptides known as ...
M. Maggioni, M. Stuknytė, S. Cattaneo, P. De Luca, A. Ferraretto, I. De Noni   +5 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Following the fate of polystyrene micro and nanobeads during in vitro digestion

Current Research in Food Science
The objective of this project was to follow the fate of nano and microplastic particles during gastrointestinal transfer. Polystyrene latex nano (60 nm) and micro (1 μm) beads were employed as model system for microplastic particles and mixed (68 mg/mL ...
Elena Arranz, Emmanouil D. Tsochatzis, Negin Hashemi, Hanne Søndergaard Møller, Milena Corredig   +4 more
doaj   +1 more source

In vitro digestion models for dietary phenolic compounds [PDF]

, 2005
The aim of this work was to develop in vitro digestion models for mimicking the physiological conditions of upper intestine and microbial conversions in the colon.
Aura, Anna-Marja, Aura, Anna-Marja; id_orcid   +1 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

In vitro digestive properties and the bioactive effect of walnut green husk on human gut microbiota

Frontiers in Microbiology
IntroductionWalnut green husk (WGH) is a waste byproduct from walnut industry. However, it is not well-known about its bioactive effect on human gut health.MethodsThis study conducted in vitro digestion and fermentation experiments to study the bioactive
Xiaolan Zhao, Xiaolan Zhao, Jiabao Ying, Zhuochen Wang, Yulu Wang, Zhen Li, Tianyi Gu, Shujun Liu, Yulong Li, Bing Liu, Fengjiao Xin, Fengjiao Xin, Boting Wen, Boting Wen   +13 more
doaj   +1 more source

Hempseed cake as a protein feed for ruminants [PDF]

, 2010
Increasing the use of locally produced protein feeds in ruminant production systems in northern Europe would be a valuable development. Hemp (Cannabis sativa L.) can be cultivated at high latitudes and cold-pressing the seeds to extract the oil produces ...
Karlsson, Linda
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

In Vitro Digestion and Fermentation Characteristics of Mochella Polysaccharides and the Preparation of Effervescent Tablets

Shipin gongye ke-ji
In order to explore in vitro digestion and fermentation characteristics of Mochella polysaccharides and develop a new type of morel polysaccharide effervescent tablet with definite efficacy ingredients, in this study, the changes in simulated saliva ...
Siyu WU, Hong CHEN, Zhiyu SHE, Guangming SONG, Liling DENG, Yi ZHAO, Geng ZHONG   +6 more
doaj   +1 more source