Results 101 to 110 of about 363,724 (308)

Release of nutrients and exorphins during in vitro static gastrointestinal digestion of spaghetti from durum wheat [PDF]

, 2014
Consumption of wheat-derived products has been linked with significant nutritional and health impacts such as the management of glycaemic index and the onset of immunological reactions.
A. Marti, V. Micard, S. Cattaneo, A. Ferraretto, P. De Luca, M.A. Pagani, I. De Noni, M. Stuknyte   +7 more
core  

The harmonized INFOGEST in vitro digestion method: From knowledge to action [PDF]

, 2015
Within the active field of in vitro digestion in food research, the COST Action INFOGEST aimed to harmonize in vitro protocols simulating human digestion on the basis of physiologically inferred conditions.
Ulleberg, EK, Pihlanto, A, Karakaya, Sibel, Recio, Isidra, Vergères, G, Ménard, Olivia, Picariello, Gianluca, Alvito, Paula, Portmann, Reto, Cattenozh, Thomas, Clemente, Alfonso, Le Feunteun, S, Rioux, Laurie Eve, JanssenDuijghuijsen, L, Picariello, G, Delgado-Andrade, Christina, Janssen Duijghuijsen, Lonneke, Tavares, Ana, Martins, C, Stoffers, H, Turgeon, S, Egger, L, Recio, I, Balance, Simon, Assunção, R, Vegarud, GE, Delgado-Andrade, C, Dupont, D, Brodkorb, Andre, Murray, B.S., Meynier, A, Egger, Lotti, Ulleberg, Ellen K., Martins, Carla, Santos, Claudia N., Brodkorb, A, Garcia-Llatas, Guadalupe, Lagarda, María Jesús, Ménard, O, Mackie, Alan R., Catttenoz, Thomas, Delgado-Andrade, Cristina, Ulleberg, E.K., Assunção, Ricardo, Murray, Brent S., Rioux, Laurie-Eve, Vegarud, G.E., Alvito, P, Feunteun, Steven, Le, Karakaya, S, Balance, S, Barberá, Reyes, Simsek, S, Comi, Irene, Santos, CN, Cattenoz, Thomas, Barberá, R, Cattenoz, T, Portmann, R, Simsekm, Sebnem, Vegarud, Gerd E., Garcia-Llatas, G, Lagarda, MJ, Lesmes, Uri, JanssenDuijghuijsen, Lonneke, Rigby, N, Rigby, Neil, Santos, C.N., Rioux, L-E, Miralles, Beatriz, Le Feunteun, Steven, Murray, BS, Simsek, Sebnem, Tavares, L, Turgeon, Sylvie, Vergères, Guy, Meynier, Anne, Clemente, A, Miralles, B, Stoffers, Helena, Comi, I, Lesmes, U, Dupont, Didier, Mackie, AR, Tavares, Lucelia, Tavares, A, Pihlanto, Anne   +86 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The application of in vitro digestion to herbs (Experimental) [PDF]

, 2022
Ανέκαθεν, τα λειτουργικά τρόφιμα θεωρούνται κομμάτια μιας σωστής διατροφής του ανθρώπου, όπως φυσικά είναι η μεσογειακή διατροφή. Βασικές τροφές που χρησιμοποιούνται στην καθημερινότητα και θεωρούνται λειτουργικά, αφού χρησιμοποιούνται για ευεργετικούς ...
Τρανούλης, Αναστάσιος
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

In vitro digestion and fermentation behaviors of polysaccharides from Choerospondias axillaris fruit and its effect on human gut microbiota

Current Research in Food Science
Choerospondias axillaris fruit has attracted more and more attention due to its various pharmacological activities, which are rich in polysaccharides. This study investigated the in vitro saliva-gastrointestinal digestion and fecal fermentation behaviors
Jinjiao Dong, Wenjun Wang, Guodong Zheng, Nansheng Wu, Jingjing Xie, Shiyi Xiong, Panting Tian, Jingen Li   +7 more
doaj   +1 more source

Breakdown of Solid Foods During in Vitro Gastric Digestion [PDF]

, 2022
Food breakdown during gastric digestion influences gastric emptying, satiety, and nutrient bioaccessibility. However, the engineering design of foods for targeted breakdown has remained a challenge.
Swackhamer, Clay
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

A first step towards a consensus static in vitro model for simulating full-term infant digestion [PDF]

, 2018
In vitro alternatives to clinical trials are used for studying human food digestion. For simulating infant digestion,only a few models, lacking physiological relevance, are available.
De Oliveira, S. C., S.C. De Oliveira, O. Ménard, Ménard, Olivia, de Oliveira, Samira Cássia, N. Dellarosa, Carrière, F., Capozzi, F., A. Deglaire, C. Bourlieu, Laghi, L., Ménard, O., De Oliveira, S.C., Deglaire, A, Dellarosa, N., Deglaire, Amélie, D. Dupont, Bourlieu-Lacanal, Claire, Dupont, Didier, Dupont, D., F. Capozzi, Bourlieu, C., L. Laghi, F. Carrière   +23 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source