Results 21 to 30 of about 256 (152)
Molecular Therapy: Nucleic Acids, 2018 Antisense oligonucleotide (AON) therapy for Duchenne muscular dystrophy has drawn great attention in preclinical and clinical trials, but its therapeutic applications are still limited due to inefficient delivery.
Mingxing Wang +4 more
doaj +1 more source
Synergistic and additive effects of epigallocatechin gallate and digitonin on Plasmodium sporozoite survival and motility. [PDF]
PLoS ONE, 2010 BackgroundMost medicinal plants contain a mixture of bioactive compounds, including chemicals that interact with intracellular targets and others that can act as adjuvants to facilitate absorption of polar agents across cellular membranes.
Janina K Hellmann +3 more
doaj +1 more source
Separation of Thylakoid Protein Complexes with Two-dimensional Native-PAGE
Bio-Protocol, 2018 The hierarchical composition and interactions of the labile thylakoid protein complexes can be assessed by sequential 2D-native gel-electrophoresis system.
Marjaana Rantala +2 more
doaj +1 more source
Journal of Lipid Research, 1974 Hepatic sterol synthesis is accelerated in animals after a single dose of allylisopropylacetamide, a chemical known to be porphyrogenic. Evidence is provided to show that enhanced sterol biosynthesis is due to an increased formation of mevalonic acid ...
Luigi Taddeini +2 more
doaj +1 more source
Isolation and identification of new constituents in milk fat
Journal of Lipid Research, 1970 After removal of cholesterol on a digitonin column, the unsaponifiable matter of milk fat was examined for alcoholic substituents. Derivatization with pyruvic acid chloride 2,6-dinitrophenylhydrazone and fractionation of the derivatives gave four main ...
C.R. Brewington +2 more
doaj +1 more source
Quantitative assessment of cytosolic Salmonella in epithelial cells. [PDF]
PLoS ONE, 2014 Within mammalian cells, Salmonella enterica serovar Typhimurium (S. Typhimurium) inhabits a membrane-bound vacuole known as the Salmonella-containing vacuole (SCV). We have recently shown that wild type S.
Leigh A Knodler +2 more
doaj +1 more source
Biosynthesis of squalene and cholesterol by cell-free extracts of adult rat brain
Journal of Lipid Research, 1969 Cell-free extracts of adult rat brain incubated with mevalonic acid-2-14C synthesize 14C-labeled nonsaponifiable fractions consisting largely of squalene-14C.
M.T. Kelley +3 more
doaj +1 more source
ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment. [PDF]
PLoS ONE, 2018 The calcium binding protein ALG-2 is upregulated in several types of cancerous tissues and cancer cell death may be a consequence of ALG-2 downregulation.
Jonas M la Cour +6 more
doaj +1 more source
Mycoplasma isolation in milk samples from dairy herds in Chile
Austral Journal of Veterinary Sciences, 2021 Mycoplasma bovine mastitis is a highly contagious disease, usually associated with clinical cases refractory to antibiotic treatment. The aim of this study was the isolation of Mycoplasma species in cattle milk samples from dairy herds in Chile.
Fernando Ulloa +3 more
doaj +1 more source
Advanced Materials, EarlyView.Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source