Results 91 to 100 of about 2,135 (155)

Correction for Li et al., "Global Transcriptional Repression of Diguanylate Cyclases by MucR1 Is Essential for Sinorhizobium-Soybean Symbiosis". [PDF]

mBio, 2021
Li ML, Jiao J, Zhang B, Shi WT, Yu WH, Tian CF.   +5 more
europepmc   +1 more source

An Oxygen-Sensing Diguanylate Cyclase and Phosphodiesterase Couple for c-di-GMP Control

, 2016
A commonly observed coupling of sensory domains to GGDEF-class diguanylate cyclases and EAL-class phosphodiesterases has long suggested that c-di-GMP synthesizing and degrading enzymes sense environmental signals.
Eduardo H. S. Sousa (1932085), Jason R. Tuckerman (1999975), Maqsudul Alam (1267698), Xuehua Wan (475915), Marie-Alda Gilles-Gonzalez (1999972), Gonzalo Gonzalez (1999969), Jennifer A. Saito (2343604)   +6 more
core   +1 more source

Diguanylate cyclase DgcP is involved in plant and human Pseudomonas spp. infections.

Environmental microbiology, 2015
Peer ...
Aragon, IM, Pérez-Mendoza, D, Moscoso, JA, Faure, E, Guery, B, Gallegos, M-T, Filloux, A, Ramos, C   +7 more
openaire   +4 more sources

Targeting biofilm formation by human pathogenic bacteria: functional and inhibition studies of diguanylate cyclases

, 2013
Bacteria react to adverse environmental stimuli by forming biofilms, difficult to eradicate and highly resistant to antimicrobials and to the host immune system. Pseudomonas aeruginosa is an opportunistic pathogen, able to invade lung of cystic fibrosis (
Giardina G, Fernicola S, CAPPELLACCI, Loredana, Rinaldo S, PETRELLI, Riccardo, TORQUATI, ILARIA, Cutruzzolà Francesca   +6 more
core  

Structure of BeF3- -modified response regulator PleD: implications for diguanylate cyclase activation, catalysis, and feedback inhibition

, 2007
Cyclic di-guanosine monophosphate (c-di-GMP) is a ubiquitous bacterial second messenger involved in the regulation of cell surface-associated traits and persistence. We have determined the crystal structure of PleD from Caulobacter crescentus, a response
Carmen Chan, Wassmann, P., Beck, A., Schirmer, Tilman, Ralf Paul, Heiko Heerklotz, Heerklotz, H., Chan, C., Paul Wassmann, Paul, Ralf, Tilman Schirmer, Jenal, U., Andreas Beck, Wassmann, Paul, Schirmer, T., Chan, Carmen, Beck, Andreas, Heerklotz, Heiko, Jenal, Urs, Urs Jenal, Paul, R.   +20 more
core   +1 more source

The Inhibitory Site of a Diguanylate Cyclase Is a Necessary Element for Interaction and Signaling with an Effector Protein

, 2016
Many bacteria contain large cyclic diguanylate (c-di-GMP) signaling networks made of diguanylate cyclases (DGCs) and phosphodiesterases that can direct cellular activities sensitive to c-di-GMP levels.
Giglio, Krista M, Dahlstrom, Kurt M, O\u27Toole, George A, Sondermann, Holger   +3 more
core   +1 more source

Exploring Cyclic Diguanylate Signalling in Marine Roseobacters

, 2015
The secondary messenger cyclic diguanosine monophosphate (cyclic diguanylate or cyclic-di-GMP) is regarded as a key regulator of traits involved in transition of bacteria from a motile to a sessile lifestyle.
Regalia, Raymond
core   +1 more source

Protein allostery. computational characterization of diguanylate cyclase PleD

, 2009
In biology, accurate cellular regulation in response to environmental signals is crucial for the fitness of organisms. On the molecular level the modulation of protein activity is often achieved by the binding of a signaling molecule or by covalent modifications such as phosphorylation by kinases.
openaire   +2 more sources

Discovering selective diguanylate cyclase inhibitors: From PleD to discrimination of the active site of cyclic-di-GMP phosphodiesterases

, 2017
One of the most important signals involved in controlling biofilm formation is represented by the intracellular second messenger 3',5'-cyclic diguanylic acid (c-di-GMP). Since the pathways involved in c-di-GMP biosynthesis and breakdown are found only in
S. Rinaldo, Giardina, G., F. Mantoni, A. Paiardini, Paiardini, A., Rinaldo, S., Cutruzzolã , Francesca, Mantoni, F., Alessio Paone, Francesca Cutruzzolà, Paone, Alessio, G. Giardina   +11 more
core   +1 more source

A WYL domain transcription factor regulates Lactiplantibacillus plantarum intestinal colonization via perceiving c-di-GMP

Nature Communications
Cyclic diguanosine monophosphate (c-di-GMP) functions as a crucial bacterial second messenger to control diverse biological functions. Although numerous studies have reported the health effects of Lactiplantibacillus plantarum, the regulatory role of c ...
Quan Guo, Guangqiang Wang, Leijie Zheng, Hui Xue, Ruimin Wang, Yajing Fang, Jiachao Zhang   +6 more
doaj   +1 more source