Results 51 to 60 of about 11,186 (206)

Evaluation of a sticky trap for collecting Aedes (Stegomyia) adults in a dengue-endemic area in Thailand. [PDF]

, 2008
Development of new operational techniques for collection and monitoring of adult Stegomyia mosquitoes is considered a pressing need for surveillance and prevention of arboviruses.
Valerio, Laura, Jones, JW, Facchinelli, Luca, Scott, Thomas W, Koenraadt, CJ, Kijchalao, U, della Torre, A, Koenraadt, Constantianus JM, Jones, James W, Valerio, L, Scott, TW, Facchinelli, L, Fanello, C, della Torre, Alessandra, Fanello, Caterina, Kijchalao, Udom   +15 more
core   +1 more source

Dihydroartemisinin Exerts Antifibrotic and Anti-Inflammatory Effects in Graves’ Ophthalmopathy by Targeting Orbital Fibroblasts

Frontiers in Endocrinology, 2022
Graves’ ophthalmopathy (GO) is a common orbital disease that threatens visual function and appearance. Orbital fibroblasts (OFs) are considered key target and effector cells in GO.
Shenglan Yang, Xing Wang, Wei Xiao, Zhihui Xu, Huijing Ye, Xiaotong Sha, Huasheng Yang   +6 more
doaj   +1 more source

Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children.

, 2006
In Rwanda, amodiaquine+sulfadoxine/pyrimethamine (AQ+SP) is the current first-line treatment for malaria, introduced in 2001 as an interim strategy before the future deployment of an artemisinin-based combination treatment (ACT).
van Overmeir, C, Karema, Corine, Ngamije, D., D'Alessandro, U., Ngamije, D, Fanello, C. I., van Doren, W., van Doren, W, Karema, C., Fanello, Caterina I, Fanello, Caterina I., D'Alessandro, Umberto, Van Overmeir, C., Fanello, CI, d' Alessandro, Umberto, van Geertruyden, Jean-Pierre, Ngamije, Daniel, van Overmeir, Chantal, van Doren, Walli, D'Alessandro, U, Karema, C, van Geertruyden, JP, Van Geertruyden, J. P.   +22 more
core   +1 more source

Correction: Therapeutic efficacies of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum and chloroquine and dihydroartemisinin-piperaquine for uncomplicated Plasmodium vivax infection in Ethiopia [PDF]

, 2023
Correction to: "Therapeutic efficacies of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum and chloroquine and dihydroartemisinin-piperaquine for uncomplicated Plasmodium vivax infection ...
Solomon, Hiwot, Hwang, Jimee, Zhou, Zhiyong, Teka, Hiwot, Murphy, Matthew, Tasew, Geremew, Ezema, Bryan, Abera, Adugna, Tadesse, Mekonnen, Minta, Anna A., Assefa, Ashenaf, Sime, Heven, Girma, Samuel, Tadesse, Yehualashet, Bekele, Worku, Mohammed, Hussein, Dilu, Dereje, Svigel, Samaly Souza, Moriarty, Leah F., Anand, Anjoli, Haile, Mebrahtom, Alemayehu, Bereket Hailegiorgis, Etana, Kebede, Woyessa, Adugna   +23 more
core   +1 more source

Severe Embryotoxicity of Artemisinin Derivatives in Experimental Animals, but Possibly Safe in Pregnant Women

Molecules, 2009
Preclinical studies in rodents have demonstrated that artemisinins, especially injectable artesunate, can induce fetal death and congenital malformations at a low dose range.
Qigui Li, Peter J. Weina
doaj   +1 more source

Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial [PDF]

, 2009
BACKGROUND: Artemisinin combination therapies (ACTs) are currently the preferred option for treating uncomplicated malaria. Dihydroartemisinin-piperaquine (DHA-PQP) is a promising fixed-dose ACT with limited information on its safety and efficacy in ...
Corsi Marco, Nambozi Michael, Bassat Quique, Piola, Patrice, Nabasumba, C., Umberto D'Alessandro, Bassat, Q., D'Alessandro Umberto, Halidou Tinto, D’Alessandro, U., Clara Menéndez, Nabasumba Carolyn, Valéa Innocent, Ubben, D., Borrmann Steffen, Mulenga Modest, Corsi, M., Mulenga, Modest, Nambozi, M., Talisuna, A., Tinto, Halidou, Vale´a, I., David Ubben, Innocent Valéa, Sasi Philip, Marco Corsi, Piola Patrice, Bacchieri, Antonella, Sasi, P., Nabasumba, Carolyn, Bacchieri, A., Michael Nambozi, Ambrose Talisuna, Carolyn Nabasumba, Nambozi, Michael, Valéa, Innocent, Philip Sasi, Menéndez, Clara, Talisuna, Ambrose, Menéndez Clara, Patrice Piola, Ubben, David, Sasi, Philip, Antonella Bacchieri, Borrmann, S., Tinto Halidou, Bassat, Quique, D'Alessandro, Umberto, Tinto, H., Mulenga, M., Bacchieri Antonella, Piola, P., Borrmann, Steffen, Corsi, Marco, Talisuna Ambrose, Ubben David, Quique Bassat, Modest Mulenga, Steffen Borrmann, Mene´ndez, C.   +59 more
core   +1 more source

Targeted Lipid Nanoparticles Encapsulating Dihydroartemisinin and Chloroquine Phosphate for Suppressing the Proliferation and Liver Metastasis of Colorectal Cancer

Frontiers in Pharmacology, 2021
Antimalarial drugs Dihydroartemisinin (DHA) and chloroquine phosphate (CQ) exhibit evident anti-cancer activity, particularly as combination therapy. DHA and CQ combination therapy has been proved to exhibit higher cytotoxic effect in tumor cells and ...
Jianqing Peng, Jianqing Peng, Qin Wang, Qin Wang, Jia Zhou, Jia Zhou, Shuli Zhao, Shuli Zhao, Pan Di, Pan Di, Yan Chen, Yan Chen, Ling Tao, Ling Tao, Qianming Du, Qianming Du, Xiangchun Shen, Xiangchun Shen, Yi Chen, Yi Chen   +19 more
doaj   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Dihydroartemisinin as a Sensitizing Agent in Cancer Therapies

OncoTargets and Therapy, 2021
Cancer is one of the major threats to human health. Although humans have struggled with cancer for decades, the efficacy of treatments for most tumors is still very limited. Dihydroartemisinin (DHA) is a derivative of artemisinin, a first-line antimalarial drug originally developed in China.
Qingrong Li, Qiang Ma, Jibing Cheng, Xi Zhou, Wenjie Pu, Xiaowu Zhong, Xiaolan Guo   +6 more
openaire   +4 more sources

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, EarlyView.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source